KEGG   Streptococcus pyogenes MGAS10394 (serotype M6): M6_Spy0762
Entry
M6_Spy0762        CDS       T00191                                 
Name
(GenBank) dTDP-glucose 4,6-dehydratase
  KO
K01710  dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
Organism
spa  Streptococcus pyogenes MGAS10394 (serotype M6)
Pathway
spa00521  Streptomycin biosynthesis
spa00523  Polyketide sugar unit biosynthesis
spa00525  Acarbose and validamycin biosynthesis
spa00541  Biosynthesis of various nucleotide sugars
spa01100  Metabolic pathways
spa01110  Biosynthesis of secondary metabolites
spa01250  Biosynthesis of nucleotide sugars
Module
spa_M00793  dTDP-L-Rha biosynthesis, Glc-1P => dTDP-L-Rha
Brite
KEGG Orthology (KO) [BR:spa00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00541 Biosynthesis of various nucleotide sugars
    M6_Spy0762
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    M6_Spy0762
   01055 Biosynthesis of vancomycin group antibiotics
    M6_Spy0762
  09110 Biosynthesis of other secondary metabolites
   00521 Streptomycin biosynthesis
    M6_Spy0762
   00525 Acarbose and validamycin biosynthesis
    M6_Spy0762
Enzymes [BR:spa01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.46  dTDP-glucose 4,6-dehydratase
     M6_Spy0762
SSDB
Motif
Pfam: GDP_Man_Dehyd Epimerase NAD_binding_4 3Beta_HSD Polysacc_synt_2 RmlD_sub_bind NAD_binding_10 NmrA adh_short Sacchrp_dh_NADP KR
Other DBs
NCBI-ProteinID: AAT86897
LinkDB
Position
764717..765757
AA seq 346 aa
MYKNIIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGNRANIEAILGDRVELVVGD
IADAELVDKLAAKADAIVHYAAESHNDNSLEDPSPFIHTNFIGTYTLLEAARKYDIRFHH
VSTDEVYGDLPLREDLPGQGEGPGEKFTAETKYNPSSPYSSTKAASDLIVKAWVRSFGVK
ATISNCSNNYGPYQHIEKFIPRQITNILAGIKPKLYGEGKNVRDWIHTNDHSTGVWAILT
KGRIGETYLIGADGEKNNKEVLELILEKMGQPKDAYDHVTDRAGHDLRYAIDSTKLREEL
GWEPQFTNFSEGLEETIKWYTENETWWKAEKDAVEAKYAKTQEVIK
NT seq 1041 nt   +upstreamnt  +downstreamnt
atgtataaaaatattatcgtaactggtggagctggtttcatcggttctaactttgtacac
tatgtctacaataaccacccagatgttcatgtaactgtccttgataaattgacatatgca
ggtaaccgtgctaacattgaagctattcttggtgatcgtgttgagttagttgttggtgat
atcgctgacgctgaattggtagataaattggctgccaaagcggatgctattgttcactat
gcggctgagagccacaacgataactcattggaagatccaagtccatttatccatacaaac
tttatcggaacttacactttgcttgaagcagctcgtaaatacgatatccgtttccaccac
gtgtcaactgatgaagtttatggagatcttccacttcgtgaagaccttccaggacagggt
gaaggaccaggtgaaaaattcactgctgaaacaaaatacaatccatcatcaccttactca
tcaactaaggcagcttctgaccttatcgttaaggcatgggtacgttccttcggtgtgaaa
gcgaccatttcgaactgttcaaataactatggaccataccaacacatcgaaaaattcatt
ccacgtcaaattacaaatatcttggcaggaatcaaaccaaaactttatggtgaaggtaaa
aacgtccgtgactggattcatactaatgatcattctacaggagtatgggctattttgact
aagggtcgtatcggtgaaacataccttattggtgccgacggcgagaaaaataacaaggaa
gttcttgagcttatccttgagaaaatgggtcaaccaaaagacgcttatgatcacgtaact
gaccgtgctggtcacgatcttcgttacgctattgattctacaaaattacgtgaagaactc
ggctgggaaccacaatttacaaacttttcagaaggtttggaagaaactattaagtggtat
acagaaaatgagacatggtggaaagcagaaaaagatgctgtagaagccaagtatgctaaa
actcaagaagtgattaaataa

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