Streptococcus pyogenes MGAS10394 (serotype M6): M6_Spy1753
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Entry
M6_Spy1753 CDS
T00191
Name
(GenBank) Multimodular transpeptidase-transglycosylase PBP 2A
KO
K12555
penicillin-binding protein 2A [EC:
2.4.99.28
3.4.16.4
]
Organism
spa
Streptococcus pyogenes MGAS10394 (serotype M6)
Pathway
spa00550
Peptidoglycan biosynthesis
spa01100
Metabolic pathways
spa01501
beta-Lactam resistance
Brite
KEGG Orthology (KO) [BR:
spa00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
M6_Spy1753
09160 Human Diseases
09175 Drug resistance: antimicrobial
01501 beta-Lactam resistance
M6_Spy1753
09180 Brite Hierarchies
09181 Protein families: metabolism
01003 Glycosyltransferases [BR:
spa01003
]
M6_Spy1753
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
spa01011
]
M6_Spy1753
Enzymes [BR:
spa01000
]
2. Transferases
2.4 Glycosyltransferases
2.4.99 Transferring other glycosyl groups
2.4.99.28 peptidoglycan glycosyltransferase
M6_Spy1753
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.16 Serine-type carboxypeptidases
3.4.16.4 serine-type D-Ala-D-Ala carboxypeptidase
M6_Spy1753
Glycosyltransferases [BR:
spa01003
]
Polysaccharide
Bacterial polysaccharide (excluding LPS)
M6_Spy1753
Peptidoglycan biosynthesis and degradation proteins [BR:
spa01011
]
Peptidoglycan biosynthesis and degradation
Glycosyltransferase/DD-Transpeptidase (Class A PBP)
M6_Spy1753
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Transgly
Transpeptidase
YrhK
Motif
Other DBs
NCBI-ProteinID:
AAT87888
LinkDB
All DBs
Position
complement(1759158..1761494)
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AA seq
778 aa
AA seq
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MRFLELLQKKFFPKAYQEKQFLMHQKARLTPQHNQKQYSPNANHLDSSATKNSEQDPAIA
LQRSRAYEGSPKSRPAWLQKLEAVLPSPQHPIRRFWRRYHIGKLLMILIGTLVLLLGSYL
FYLSKTAKVSDLQDALKATTVIYDHKGEYAGSLSGQKGSYVELNAISDDLENAVIATEDR
TFYSNSGINLKRFLLAVVTAGRFGGGSTITQQLAKNAYLSQDQTIKRKAREFFLALELTK
KYSKKDILTMYLNNSYFGNGVWGVEDASQKYFGTTAANLTLDEAATLAGMLKGPEIYNPY
HSLKNATHRRDTVLGAMVDAKKITQTKAQQARAVGLKNRLADTYVGKTDDYKYPSYFDAV
ISEAIATYGLSEKDIVNNGYKVYTELDQNYQTGMQTTFNNDELFPVSAYDGSSAQAASVA
LDPKTGGVRGLIGRVNSSENPTFRSFNYATQAKRSPASTIKPLVVYAPAVASGWSIEKEL
PNTVQDFDGYQPHNYGNYESEDVPMYQALANSYNIPAVSTLNDIGIDKAFTYGKTFGLDM
SSAKKELGVALGGNVTTNPLEMAQAYAAFANNGVIHPAHLINRIENARGEVLKTFTDKAK
RVVSQSVADKMTAMMLGTFSNGTAVNANVYGYTLAGKTGTTETNFNPDLAGDQWVIGYTP
DVVISQWVGFNQTDENHYLTDSSAGTASAIFSTQASYILPYTKGSQFHVDNAYAQNGISA
VYGVNETGNQSGVDTQSIIDGLRKSAQEASQSLSKAVDQSGLRDKAQSIWKEIVDYFR
NT seq
2337 nt
NT seq
+upstream
nt +downstream
nt
atgagatttctagaacttttacaaaagaaattttttcctaaagcatatcaggaaaaacaa
ttcttaatgcatcaaaaagcgcgtttaacgccacaacacaatcaaaagcagtattcgcca
aatgccaatcatttggactcatcagctaccaaaaactcagaacaagaccctgcaatagct
ctgcaacgcagtagagcctatgaaggaagccctaaaagtcggcccgcttggttgcaaaag
ttggaagctgttttgccgtctcctcaacatccaattcggcgtttttggcgccgctatcac
atcggaaaactgctaatgattctgattggaactcttgtcttactcttaggatcatacttg
ttttacttatcaaaaacagctaaagtatctgatttacaagatgccttgaaggctacaacg
gttatttatgatcacaaaggagagtatgcaggcagtttatctggtcaaaaagggagttat
gttgagctcaacgctatttcagatgatcttgagaatgctgttattgccactgaggatagg
actttttacagtaatagcggtattaatcttaaacgcttcttattggcagtagttacggcg
ggccgctttggaggtggctcaacgattacacagcaactggctaaaaatgcttatctctca
caagatcagacaattaaacgaaaggccagagagttttttttggcgttagagttgaccaaa
aaatacagtaaaaaagatattcttactatgtaccttaacaactcctattttggaaatgga
gtttggggagttgaagatgccagtcaaaaatattttggaaccacagctgctaacttaaca
ctggatgaagctgccacattagcaggtatgctcaaaggacctgaaatatataacccttac
cattctctaaaaaatgctactcaccgtagagatactgttttaggagcgatggttgatgcc
aaaaagattacccaaacaaaagctcaacaagctagagcagtagggctaaaaaatcgctta
gctgatacttatgttggtaagacagatgactacaaatacccatcctactttgatgctgtt
attagtgaagcaatagcaacttatggtctttcagaaaaagacattgttaataatggatac
aaagtttacactgagctagatcaaaattaccaaactggcatgcagacgacttttaacaac
gatgaactatttcctgtttcagcttatgacggtagctctgctcaagcagctagtgttgct
ttagatcctaaaacaggaggtgttagaggtctgattggtcgtgtgaatagtagtgaaaat
ccgactttcagaagttttaactatgcgactcaagcaaaacgtagtcccgcatcaacaatc
aaaccactcgtggtttacgcgccagccgttgcttcaggatggtcaattgaaaaagaacta
ccaaataccgttcaagatttcgatggctatcagccacataattatggaaattatgaatca
gaagatgttcctatgtatcaagcattagcaaactcttataatattccagcagtttctaca
ttgaacgatatcggaatcgataaagcctttacctatggtaaaacatttgggttagatatg
agctctgccaaaaaagagttgggggtagctttaggtggcaacgtgacaaccaatccattg
gagatggctcaggcatatgctgcctttgccaataatggagtaatccatcctgcgcacttg
attaaccggattgaaaatgccaggggtgaagtgcttaaaacctttactgataaggctaaa
cgtgttgtcagccagtctgttgcagataagatgacagccatgatgctaggtaccttttca
aatggaacagcagtcaatgctaacgtatatggctatacactagctggtaaaacagggacg
acagaaaccaacttcaatcccgacttagcaggcgatcagtgggttattggttatacacca
gatgttgttattagtcaatgggtaggatttaatcagaccgatgaaaatcattatctaacg
gattcaagtgcaggcacggcctcagctatttttagcactcaggcatcttacattttgcct
tataccaagggcagccaatttcatgtagataatgcctacgctcaaaatggtatttcagct
gtttatggagtcaatgaaacaggtaatcaatcaggagttgacactcaatctattattgat
ggtttaagaaaatcagcacaagaagcttcgcaatcactatcaaaagcagtcgatcagtca
gggttacgtgataaagcccaatctatttggaaagagattgttgactattttagatag
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