Streptomyces pactum: B1H29_26920
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Entry
B1H29_26920 CDS
T07142
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
spac
Streptomyces pactum
Pathway
spac00300
Lysine biosynthesis
spac00550
Peptidoglycan biosynthesis
spac01100
Metabolic pathways
spac01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
spac00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
B1H29_26920
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
B1H29_26920
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
B1H29_26920
Enzymes [BR:
spac01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
B1H29_26920
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DHHA1
DUF561
Motif
Other DBs
NCBI-ProteinID:
AQS70028
UniProt:
A0A1S6JE45
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Position
6283187..6284602
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AA seq
471 aa
AA seq
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MIALSLAEIAEVVGGRMHDIPDASAQVTGPVVRDSREAGPGSLFVAFAGERADGHDFAPA
VVEAGAVAVLGSRPVGVPAIVVDDVQAALGALARHVVRRLGTTLVALTGSAGKTSTKDLI
AQVLRRKAPTVFTPGSLNNEIGLPLTALTATEETKFLVLEMGARGIGHIRYLAELTPPKV
GLVLNVGSAHIGEFGGREQIAQAKGELVEALPPAEEGGAAILNADDPLVRAMASRTKAKV
ILFGESDEADVSAENVRLTDSGQPSFRLHTPSGASDVTMRLYGEHHVSNALAAAAVAHEL
GMSADEIATALSEAGSLSRWRMEVTERPDGVTVVNDAYNANPESMRAALRALVAMGKGRR
TWAVLGKMAELGDEALAEHDAVGRLAVRLNVSKLVAVGGREARWLQLGAYNEGSWGEESV
HVSDAQAAVDLLRSELRPGDVVLVKASRSVGLESVATALLETGAEGEVAAR
NT seq
1416 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctctctcgccgagatcgcagaagtcgtcggcgggcggatgcacgacata
ccggacgcgtccgcgcaggtcaccgggccggtcgtccgggactcgcgggaagcggggccc
ggcagcctcttcgtcgccttcgcgggcgagcgggcggacggccacgacttcgcgccggcg
gtcgtcgaggcgggcgcggtggccgtgctcggctcccgccccgtcggcgtgcccgcgatc
gtcgtggacgacgtccaggccgccctcggcgccctcgcccggcacgtcgtccggcgcctc
ggcaccaccctcgtggccctcaccgggtccgccggcaagaccagcaccaaggacctcatc
gcccaggtgctgcgccgcaaggcgcccacggtcttcacgcccggctccctgaacaacgag
atcgggctgccgctcaccgcgctcactgccaccgaggagacgaagttcctcgtcctggag
atgggcgcccgcggcatcggccacatccgctacctcgccgagctgaccccgccgaaggtc
ggcctcgtcctcaacgtcggctccgcgcacatcggcgagttcggcggccgggagcagatc
gcccaggccaagggcgagctcgtcgaggcgctgccgcccgccgaagagggcggcgccgcg
atcctcaacgcggacgatcccctcgtacgcgccatggcctcccgaacgaaggcgaaggtg
atccttttcggagagtccgacgaagcggacgtgtccgccgagaacgtgcgactcacggac
agcggacagccttccttcaggcttcacacaccctccggtgcaagcgatgtgaccatgcgc
ctgtacggtgagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccacgagttg
ggcatgtccgcagacgagatcgccaccgcgctctccgaggcgggctccctctcccgctgg
cggatggaggtcaccgagcgcccggacggcgtgacggtcgtcaacgacgcctacaacgcg
aaccccgagtccatgcgagccgccctgcgcgcgctcgtggcgatgggcaaggggcgtcgt
acgtgggcggtgctcggcaagatggccgagctcggggacgaggcgctcgccgagcacgac
gcggtcgggcggctcgccgtccggctcaacgtcagcaagctcgtcgcggtcgggggcagg
gaagcccgatggctgcaactgggcgcatataacgagggttcgtggggtgaggagtcggtg
cacgtgtccgacgcacaggcggcggtcgacctgttgcgcagcgagttgcgcccaggggac
gtcgtgctcgtgaaggcgtcccgttcggtgggtctggagagcgtcgcgacggcgctgctc
gagaccggcgccgagggtgaggttgccgcccgatga
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