Streptomyces paludis: DVK44_06390
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Entry
DVK44_06390 CDS
T06964
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
spad
Streptomyces paludis
Pathway
spad00300
Lysine biosynthesis
spad00550
Peptidoglycan biosynthesis
spad01100
Metabolic pathways
spad01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
spad00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
DVK44_06390
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
DVK44_06390
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
DVK44_06390
Enzymes [BR:
spad01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
DVK44_06390
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AXG77380
UniProt:
A0A345HL06
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Position
complement(1468902..1470332)
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AA seq
476 aa
AA seq
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MIALSLAEIAAIVGGQPHDIPDQAVLVTGSVVYDSRAVEPGGLFAAFAGERVDGHDYARG
AVAAGAVAVLATRPVGVPAIVVDDVVQALGALARTVVERLGATPVALTGSAGKTSTKDLI
AQLLRRAGPTVWPEGNLNNEIGLPITALRAVEDTRYLVLEMGARYIGDIRYLTGLVPPRI
GLVLNVGTAHIGEFGGREQIAQAKGEMVESLPSAEQGGIAVLNADDPLVRAMASRTQARV
VLFGESGEADVRAENVRLTATGQPAFRLRTPSGCSDVTLRLYGEHHVSNALASAAVAHEL
GMSAEEIAVALSEAGTLSRWRMEVTERSDGVTIVNDAYNANPESMRAALRALVAMGGASR
PAGSRTWAVLGPMAELGDESLAEHDAVGRLAVRLNVSKLVAVGGREASWLRLGAYNEGSW
GEESVHVSDAQAAVDLLRSELRPGDVVLVKASRSVGLERVAQALLENATEGEVAGR
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctccctcgccgagatcgccgccatcgtcggcgggcagccgcacgacata
ccggatcaggccgttctcgtcaccggatccgttgtctacgactcccgcgcggtcgagccc
ggcggcctgttcgccgcgttcgccggtgagcgcgtcgacggccacgactacgcgcgcggc
gccgtcgcggcgggcgcggtggccgtgctggccacccgccccgtcggcgtgcccgccatc
gtcgtggacgatgtcgtccaggccctcggcgccctcgcccgtaccgtcgtggagcgcctc
ggcgccacccccgtcgcgctcaccgggtcggcgggcaagaccagcaccaaggacctgatc
gcccagctgctgcggcgcgcgggtcccacggtgtggccggaaggcaacctcaacaacgag
atcggtctgcccatcaccgccctgcgggccgtcgaggacacccgctacctcgtgctcgaa
atgggcgcgcggtacatcggggacatccgctacctcaccgggctcgtaccgcccaggatc
ggcctcgtcctgaacgtcggcaccgcgcacatcggcgagttcggcggccgggagcagatc
gcccaggccaagggcgagatggtggagtccctgccctccgccgaacagggcgggatcgcc
gtactgaacgccgacgacccgctggtccgcgccatggcgtcgcgcacacaggcgcgcgtc
gtgctgttcggagagtcgggcgaagcagacgtacgggcagagaacgtccgcctcaccgcc
acgggacagcccgcgttccgccttcgaacaccctccgggtgcagcgacgtgacgctgcgg
ctgtacggtgagcaccacgtgtcgaacgcgctcgcctcggccgccgtcgcccatgagttg
ggcatgtccgccgaagagatcgccgtggcgctctccgaggcgggaaccctctcccgctgg
cgtatggaggtcaccgagcgctcggacggcgtgacgatcgtcaacgacgcctacaacgcg
aaccccgaatccatgagggcggcgctccgtgcgctggtcgccatgggcggtgcctcacgg
cccgcggggagccgtacctgggcggtgctcggcccgatggccgagctgggggacgaatcg
ctcgccgagcacgacgcggtcggacggctcgccgtccggctcaacgtcagcaagctcgtg
gcagtcgggggcagggaagcgtcctggctgcgattgggcgcttacaacgagggttcgtgg
ggtgaggagtcggtgcacgtgtccgacgcgcaggcggcggtcgacctgttgcgcagtgaa
ctgcgtccgggagacgtcgtgctggtgaaggcttccaggtcggtcggtcttgagcgggtc
gcccaggcactgctggagaacgccaccgagggcgaggtcgccggccgatga
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