Streptomyces paludis: DVK44_25735
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Entry
DVK44_25735 CDS
T06964
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
spad
Streptomyces paludis
Pathway
spad00290
Valine, leucine and isoleucine biosynthesis
spad00660
C5-Branched dibasic acid metabolism
spad01100
Metabolic pathways
spad01110
Biosynthesis of secondary metabolites
spad01210
2-Oxocarboxylic acid metabolism
spad01230
Biosynthesis of amino acids
Module
spad_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
spad00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
DVK44_25735 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
DVK44_25735 (leuC)
Enzymes [BR:
spad01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
DVK44_25735 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
DVK44_25735 (leuC)
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GFIT
Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
AXG80509
UniProt:
A0A345HUY5
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Position
5817016..5818455
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AA seq
479 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRKDGRQVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRIQLETLRKNCADFGVRLHSLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLARPRTMAITVDGELPADVTA
KDLILAVIARIGTGGGQGYILEYRGSAIEKLSMEARMTICNMSIEAGARAGMIAPDDTTF
AYLKGRDHAPTGEDWDAAVAYWRTLRTDDDAVFDAEVVIDATALAPFVTWGTNPGQGAPL
SSNVPDPASYEDASERLAAEKALEYMGLTAGQALRDIKVDTVFVGSCTNGRIEDLRSAAS
LLDGRKVADGVRMLVVPGSVRVALQAVAEGLDKVFTAAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLSGAAAGDRTPAGAR
NT seq
1440 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgaccatgtcgtccggcgcgcagagggc
gagcccgacctcctcttcatcgatctgcacctgctgcacgaggtgaccagcccccaggcg
ttcgacggcctgcgcaaggacggccgccaggtccggcggctcgacctcaccatcgcgacc
gaggaccacaacaccccgacgctcgacatcgacaagcccatcgccgacccggtctcccgg
atccagctggagaccctccgcaagaactgcgccgacttcggtgtgcggctgcactcgctg
ggcgatgtcgagcagggcgtcgtccatgtcgtcggcccccagctggggctgacccagccc
ggcaccaccgtggtctgcggcgacagccacacctccacccacggcgccttcggcgcgctg
gcgttcggcatcggcaccagccaggtcgagcatgtcctggccacccagacgctgccgctg
gcccgcccccggaccatggccatcacggtcgacggcgaactgcccgccgatgtcaccgcc
aaggacctgatcctcgccgtcatcgcccggatcggcaccggcggcggccagggctacatc
ctcgaataccggggctcggccatcgagaaactctcgatggaggcccggatgaccatctgc
aacatgtccatcgaggccggcgcccgggcgggcatgatcgcccccgacgacaccaccttc
gcgtacctcaagggccgcgaccacgccccgacgggcgaggactgggacgccgcggtcgcc
tactggcggacgctgcgcaccgacgacgacgcggtcttcgacgccgaggtcgtcatcgac
gccaccgccctcgccccgttcgtcacctggggcaccaaccccggccagggcgcgccgctc
tcctcgaacgtccccgacccggcttcgtacgaggacgcttcggagcgcctcgccgccgaa
aaggccctggaatacatggggttgaccgccgggcaggcgctgcgcgacatcaaggtcgac
accgtcttcgtaggctcctgcaccaacggccgtatcgaggacctgcgctcggcggcctcg
ctgctggacgggcgcaaagtcgccgacggcgtacggatgctggtcgtccccggctcagtc
cgggtcgccctccaggccgtggccgagggcctcgacaaggtcttcaccgccgcgggggcc
gaatggcggcacgcgggctgctcgatgtgtctgggcatgaaccccgaccaactcgcgccc
ggtgagcgctccgcgtccacgtccaaccgcaacttcgagggcaggcagggcaagggcggc
cggacccatctggtctctccgcaggtcgccgccgccaccgccgtactgggccatctggcc
tcgcccgcagacctgtccggcgccgcagccggcgaccgtacgcccgctggagcgcgataa
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