Sphingomonas panacis: AWL63_11835
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Entry
AWL63_11835 CDS
T04760
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
span
Sphingomonas panacis
Pathway
span00300
Lysine biosynthesis
span00550
Peptidoglycan biosynthesis
span01100
Metabolic pathways
span01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
span00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
AWL63_11835
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
AWL63_11835
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
AWL63_11835
Enzymes [BR:
span01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
AWL63_11835
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AOH84557
UniProt:
A0A1B3ZAW5
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All DBs
Position
2629847..2631220
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AA seq
457 aa
AA seq
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MTLWTSAEIATATGGTASTDFTVSGVAFDSREVGPGDLFIALKGEATDGHRFLDQCFAQG
AAGAIVSADTAHPHVRVADTTAALEALARASRARTHAKIIGVTGSVGKTGTKEALFAALD
RGARGQAHRSVKSYNNHTGVPLSLARMPAQSRFGVFEMGMNHSGELAALTRIVRPHIALV
TAIAPAHTAFFSGEAAIADAKGEIFQGLEPGGTAIIPFDSPHRDRLIAAAAPYAAHIVTF
GSGVGADVRAIETMPVASGGTFVTARLGESELNYTISQPGAHWVSNTLAVLAAVRAAGGD
LALAGLALAEMEGLTGRGARFTVPVGAGEALVIDESYNANPSSMRATLAVLAQQDATRKL
VVLGEMRELGADSDAYHAALAGPIRAAGVETGILVGESMRALSNALEGQGDFVHVPDAAA
AQRSLRALLAPGDAVLIKGSNGVGLSAVVAALRSGIG
NT seq
1374 nt
NT seq
+upstream
nt +downstream
nt
gtgaccctctggacttccgccgagatcgccaccgcgaccggtggcaccgcgtccaccgac
ttcaccgtctccggtgtcgcgttcgattcgcgcgaagtcggccccggcgacctgttcatc
gcgctgaagggtgaggctaccgacggccatcgcttcctcgaccagtgcttcgcgcaaggc
gcagccggcgcgatcgtcagcgccgacaccgcgcacccgcacgttcgcgtcgccgatacg
accgcagcgctggaagcgctcgcccgcgcgtcgcgtgcgcgcacgcacgcgaagatcatc
ggcgtcaccggctcggtcggcaagaccggcaccaaggaagcgctgttcgccgcgctcgat
cgtggcgcgcggggccaagcgcatcgctctgtcaaaagctacaacaaccataccggcgtg
ccgctgagcctcgcgcggatgcccgcgcagagccgtttcggcgtgttcgaaatgggcatg
aaccattctggcgaactcgccgcgctcacccgcatcgtgcgcccgcatatcgccttggtg
acggcgattgcgcccgcgcacaccgccttcttctcgggagaggccgcgatcgccgacgcc
aagggcgagatcttccagggcctcgaacccggcggcaccgcgatcatcccgttcgacagc
ccgcaccgcgaccggctgatcgccgccgccgcgccttacgccgcgcacatcgtcaccttc
ggctcgggcgtgggcgccgatgtccgcgcgatcgagacgatgccggtcgcctcgggcggc
acgttcgtcaccgcgcggctcggggagagcgaactcaattacacgatcagccagcccggc
gcgcattgggtgtcgaacacgctcgcggtgctggcggcggtgcgcgcggcgggcggcgac
ctcgcgctcgccggtctcgcgcttgccgagatggaggggctgacgggtcgcggcgcgcgc
ttcaccgttccggtcggtgcgggcgaagcgctggtgatcgacgaaagctacaacgccaat
ccctcgtcgatgcgcgccacgctggcggtgctggcgcagcaggacgcaacccgcaaactc
gtcgtgctcggcgagatgcgcgagttgggcgcggatagcgacgcctatcacgctgcgctt
gccgggccgatccgcgcggcgggcgtcgagacgggcatattggtcggtgaatccatgcgc
gcgctttcgaacgcgcttgaggggcagggcgatttcgtccatgtgcccgacgccgcagcc
gcgcagcggagcctccgggcgctgctcgcgccgggcgatgcggttctcatcaagggttcg
aacggcgtggggttgtcggcggtggtcgcggccttgcggagcgggattgggtaa
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