Streptomyces parvulus: Spa2297_23540
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Entry
Spa2297_23540 CDS
T04685
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
spav
Streptomyces parvulus
Pathway
spav00290
Valine, leucine and isoleucine biosynthesis
spav00660
C5-Branched dibasic acid metabolism
spav01100
Metabolic pathways
spav01110
Biosynthesis of secondary metabolites
spav01210
2-Oxocarboxylic acid metabolism
spav01230
Biosynthesis of amino acids
Module
spav_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
spav00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
Spa2297_23540
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Spa2297_23540
Enzymes [BR:
spav01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
Spa2297_23540
4.2.1.35 (R)-2-methylmalate dehydratase
Spa2297_23540
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Paralog
GFIT
Motif
Pfam:
Aconitase
BON_like
Motif
Other DBs
NCBI-ProteinID:
ANJ09682
UniProt:
A0A191V426
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All DBs
Position
5182084..5183514
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AA seq
476 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRKSGRPVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRAQLETLRKNCAEFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLVRPKTMAITVNGELPDGVTA
KDLILAIIAKIGTGGGQGYVLEYRGEAIEKLSMEARMTICNMSIEAGARAGMIAPDATTF
AYLQGRPHAPEGADWDAAVEYWKTLRTDDDAEFDAEVVIEAAELSPFVTWGTNPGQGAPL
SADVPDPASYEDASERFAAEKALEYMGLEAGQPLRSISVDTVFVGSCTNGRIEDLRAAAE
IVRDRKVAEGVRMLVVPGSARVGLQAVSEGLDVVFKEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLAATDVPTPAGV
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgaccacgtcgtccggcgcgccgagggc
gagcccgacctcctcttcatcgatctgcacctgctgcacgaggtgaccagcccgcaggcc
ttcgacggcctccgcaagagcggccgcccggtgcggcggctcgacctgaccatcgccacc
gaggaccacaacaccccgacgctcgacatcgacaagcccatcgcggacccggtctcccgg
gcccagctggagacgctgcgcaagaactgcgcggagttcggcgtccggctgcacccgctg
ggcgacgtcgagcagggcgtcgtgcacgtggtcggcccccagctgggcctgacccagccc
ggcaccaccgtggtctgcggcgactcgcacacgtcgacgcacggcgcgttcggcgcgctg
gccttcggcatcggcacctcccaggtcgagcacgtgctggccacccagacgctgcccctg
gtccgcccgaagaccatggcgatcaccgtcaacggcgaactgcccgacggcgtcaccgcc
aaggacctgatcctcgcgatcatcgcgaagatcggcaccggcggcggccagggctacgtc
ctggagtaccggggcgaggccatcgagaagctctcgatggaggcccgcatgaccatctgc
aacatgtcgatcgaggccggcgcccgcgccggcatgatcgcccccgacgccaccaccttc
gcctacctccagggccgtccgcacgcccccgagggcgccgactgggacgcggccgtcgag
tactggaagacgctgcgcacggacgacgacgccgagttcgacgcggaggtcgtcatcgag
gccgccgaactgtcgccgttcgtcacctggggcaccaacccaggtcagggtgcgccgctt
tccgccgacgtccccgaccccgcttcgtacgaagacgcttcggagcgcttcgccgccgaa
aaggccctggagtacatggggttggaggccggtcagccgctgcgctccatcagtgtggac
accgtcttcgtaggttcctgcaccaacggccgcatcgaggacctgcgcgccgccgccgag
atcgtgcgggaccgcaaagtcgccgagggcgtacggatgctggtcgtccccggctcggcg
cgggtcggcctccaggccgtctccgagggcctggacgtggtcttcaaggaggccggcgcc
gaatggcggcacgcgggctgctcgatgtgcctgggcatgaacccggaccagctggccccg
ggagagcgctccgcctccacctccaaccgcaacttcgaggggcgccagggcaagggcggc
cgcacccacctggtgtcgccgcaggtcgcggccgcgacggcggtcctgggccatctggcc
tccccggccgacctcgccgccaccgacgtccccacgcccgctggagtctga
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