Streptococcus pneumoniae D39 (virulent serotype 2): SPD_0057
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Entry
SPD_0057 CDS
T00413
Symbol
purH
Name
(GenBank) bifunctional purine biosynthesis protein PurH
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
spd
Streptococcus pneumoniae D39 (virulent serotype 2)
Pathway
spd00230
Purine metabolism
spd00670
One carbon pool by folate
spd01100
Metabolic pathways
spd01110
Biosynthesis of secondary metabolites
Module
spd_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
spd00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
SPD_0057 (purH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
SPD_0057 (purH)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
spd04147
]
SPD_0057 (purH)
Enzymes [BR:
spd01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
SPD_0057 (purH)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
SPD_0057 (purH)
Exosome [BR:
spd04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
SPD_0057 (purH)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Motif
Other DBs
NCBI-ProteinID:
ABJ54358
UniProt:
Q04N19
LinkDB
All DBs
Position
53975..55522
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AA seq
515 aa
AA seq
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MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGVETIAIDDVTGFPEMMD
GRVKTLHPNIHGGLLARRDLDSHLEAANENQIELIDLVVVNLYPFKETILKPDVTYADAV
ENIDIGGPSMLRSAAKNHASVTVVVDPADYTVVLDELSANGETTYETRQRLAAKVFRHTA
AYDALIAEYFTAQVGESKPEKLTLTYDLKQAMRYGENPQQDADFYQKALPTDYSIASAKQ
LNGKELSFNNIRDADAAIRIIRDFKDRPTVVALKHMNPCGIGQADDIETAWDYAYESDPV
SIFGGIAVLNREVDAATAEKMHGVFLEIIIAPSYTDEALAILINKKKNLRILALPFNAQE
ASEVEAEYTGVVGGLLVQNQDVVKESPADWQVVTKRQPTETEATALEFAWKAIKYVKSNG
IIVTNDHMTLGVGPGQTNRVASVRLAIDQAKDRLDGAVLASDAFFPFADNVEEIAKAGIK
AIIQPGGSVRDQESIEAADKYGLTMVFTGVRHFRH
NT seq
1548 nt
NT seq
+upstream
nt +downstream
nt
atgactaaacgcgtcttaatcagcgtctcagacaaagcgggcattgttgaatttgcccaa
gaactaaaaaaacttggttgggagattatctcgacaggtggaactaaggttgcccttgat
aatgctggggtggagaccattgcgatcgatgatgtgacgggcttcccagagatgatggat
ggccgtgttaagactcttcatccaaatatccacgggggtcttctcgctcgtcgtgatttg
gatagccacttggaagcagccaatgagaaccaaattgagcttattgaccttgtagtggtc
aacctttatcctttcaaggaaacgattctcaaaccagacgtgacgtacgctgatgctgtg
gagaatattgatattggtgggccatctatgcttcgttcagcagcgaagaatcatgccagc
gtgacggttgtggtagaccctgctgactatacagtggttttggacgagttgtcagccaat
ggtgaaacgacttacgaaacgcgtcaacgtttggcagccaaggttttccgtcacacagcg
gcttatgacgctttgattgcagaatacttcacagctcaagtgggcgaaagtaaacctgaa
aagttgaccttgacctatgacctaaaacaagctatgcgttatggggaaaatccccagcag
gatgcggacttctaccagaaagctttgccgactgattactccattgcatcagccaaacag
cttaacggtaaggaattgtcattcaacaatatccgcgatgcagatgctgccattcgtatt
atccgtgacttcaaagaccgtccaaccgttgtggctctcaagcatatgaatccatgtggt
atcggccaggcggatgacatcgagacggcttgggattatgcttatgagtctgacccagtg
tctatctttggtggtatcgctgttcttaaccgtgaggtggatgctgcgacagctgagaag
atgcacggcgttttcctcgaaatcatcattgcaccaagctatacggatgaagcgctagcc
attttgatcaataaaaagaaaaacttgcgtatccttgccttgccatttaatgctcaagag
gctagcgaagtggaagcagaatacacaggtgtagtcggtggacttctcgtgcaaaatcaa
gacgtggtcaaggaaagcccagctgactggcaagtggtgaccaaacgtcagccaaccgag
acagaagcgactgctcttgagttcgcttggaaggctatcaagtacgtcaaatcaaatggt
attatcgtgaccaacgaccacatgacacttggtgttggtccaggtcaaaccaaccgtgtg
gcttctgttcgccttgccattgaccaagccaaagatcgtctggacggggcggtccttgct
tcagatgccttcttcccatttgcggataacgtggaagaaatcgccaaagcaggaattaag
gccatcatccagcccggtggctctgtccgtgaccaagaatccatcgaagcagcggataaa
tacggcttgactatggtctttacaggtgtgagacattttagacattaa
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