Streptococcus pneumoniae D39 (virulent serotype 2): SPD_0062
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Entry
SPD_0062 CDS
T00413
Symbol
purB
Name
(GenBank) adenylosuccinate lyase
KO
K01756
adenylosuccinate lyase [EC:
4.3.2.2
]
Organism
spd
Streptococcus pneumoniae D39 (virulent serotype 2)
Pathway
spd00230
Purine metabolism
spd00250
Alanine, aspartate and glutamate metabolism
spd01100
Metabolic pathways
spd01110
Biosynthesis of secondary metabolites
spd01232
Nucleotide metabolism
spd01240
Biosynthesis of cofactors
Module
spd_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
spd_M00049
Adenine ribonucleotide biosynthesis, IMP => ADP,ATP
Brite
KEGG Orthology (KO) [BR:
spd00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
SPD_0062 (purB)
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
SPD_0062 (purB)
Enzymes [BR:
spd01000
]
4. Lyases
4.3 Carbon-nitrogen lyases
4.3.2 Amidine-lyases
4.3.2.2 adenylosuccinate lyase
SPD_0062 (purB)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Lyase_1
ADSL_C
Motif
Other DBs
NCBI-ProteinID:
ABJ54919
UniProt:
A0A0H2ZQC4
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All DBs
Position
59175..60473
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AA seq
432 aa
AA seq
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MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKEDVALIRKKADFDIDRIL
EIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAYGYLYKQANDIIRRDLENF
TNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSEMKRNIERFEHAAAGVEAGKI
SGAVGNFANIPPFVEEYVCNKLGIRAQEISTQVLPRDLHAEYFAVLASIATSIERMATEI
RGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSENMTGLARVIRGHMITAYENVALWHE
RDISHSSAERIITPDTTILIDYMLNRFGNIVKNLTVFPENMIRNMNSTFGLIFSQRAMLT
LIEKGMTREQAYDLVQPKTAYSWDNQVDFKPLLEADSEVTSRLTQEEIDEIFNPVYYTKR
VDDIFERLGLGD
NT seq
1299 nt
NT seq
+upstream
nt +downstream
nt
atgatcaaccgttactctcgccctgagatggcgaatatttggagtgaagaaaataaatac
cgtgcttggcttgaggtggaaatcctctctgacgaggcatgggctgagttgggggaaatc
cctaaggaagatgtggctttgattcgcaagaaggcggactttgacatcgaccgtattttg
gaaattgagcaggagacgcgccacgatgtggtggctttcacgcgtgcggtttctgagact
cttggtgaagagcgcaagtgggttcactatgggttaacttctaccgacgtggtggatact
gcttatggttacctctacaagcaggccaacgacatcatccgtcgtgaccttgaaaacttc
actaatatcatcgctgacaaggccaaggagcacaagttcaccatcatgatggggcgtact
catggtgtgcacgctgagccgacaacttttggtcttaaattggcaacttggtatagcgaa
atgaaacgcaatatcgagcgtttcgagcatgcggctgctggtgtagaagctggtaagatt
tctggtgcggttgggaactttgccaatatcccaccatttgtagaggagtatgtctgcaac
aagcttggtatccgtgctcaagaaatctctacacaagtccttcctcgtgaccttcacgct
gagtactttgcagttcttgccagcattgcgacttcaatcgaacgtatggcgactgagatt
cgtggtctacaaaaatctgagcaacgcgaagtagaagagttctttgctaaagggcaaaaa
gggtcttcagcaatgcctcacaaacgcaacccaatcggttctgaaaatatgactggtctg
gcgcgtgtcattcgtggtcacatgattacggcttatgaaaacgtcgctctctggcacgaa
cgcgatatttcccactcatcagctgagcgtatcatcacaccagatacgaccattttgatt
gactacatgctcaaccgttttggaaatatcgtcaagaacttgacagtcttcccagaaaat
atgatccgaaacatgaactcgacttttggtcttatctttagccaacgggctatgttgaca
ttgattgaaaaaggcatgacccgtgagcaagcctatgacttggtgcaaccaaaaacagcc
tactcttgggacaaccaagtagactttaaaccacttcttgaggcagattcagaagtaaca
tcacgtctcactcaagaagaaatcgatgaaatcttcaacccagtttattacaccaaacga
gtggatgatatctttgaacgtcttggactaggtgattaa
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