Streptococcus pneumoniae D39 (virulent serotype 2): SPD_0270
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Entry
SPD_0270 CDS
T00413
Name
(GenBank) folylpolyglutamate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
spd
Streptococcus pneumoniae D39 (virulent serotype 2)
Pathway
spd00790
Folate biosynthesis
spd01100
Metabolic pathways
spd01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
spd00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
SPD_0270
Enzymes [BR:
spd01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
SPD_0270
6.3.2.17 tetrahydrofolate synthase
SPD_0270
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Polysacc_deac_2
Motif
Other DBs
NCBI-ProteinID:
ABJ55041
UniProt:
A0A0H2ZQI4
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All DBs
Position
269018..270340
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AA seq
440 aa
AA seq
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MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHIGGTNGKGSTIAFLKKM
LEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADYQSLLEGEAVANLQGTTEF
EIITALAYDYFASEQVDVAIMEVGMGGLFDSTNVCQPILTGITTIGLDHVALLGDTLEAI
AEQKAGIIKQGMPLVTGRIAPEALAVIDRIAEGKDAPRLAYGTDYQVRHQESVVTGEVFD
YTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQEDGRELASNDFLGQALEETSWPGRL
EIVSRDPLMILDGAHNPHAIKALLVTLQERFADYHKEILFTCIKTKALEDMLDLLGAMPD
TELTLTHFADSRATDESVLKEAAKSRNLSYQDWHDFLEQNVTDKKEEKQTVRIVTGSLYF
LSQVRVYLMERKNENGYTKD
NT seq
1323 nt
NT seq
+upstream
nt +downstream
nt
atgaaagaaattgaaaacaatcaatggattgctaactaccggacggatcaaccgcatttt
ggcttggaacgaatggtggaactgttagctttgcgtggcaatccccatctcaaactcaag
gtcctccatatcggaggaactaacggcaagggctcgactattgcttttttgaaaaagatg
ctagaaaagctagggctgagagttggcgtgtttagctcgccctatctcattcattacaca
gaccagattagcatcaatggggaatcgatctcagaagcgaggctagaagctctcatggca
gactatcagtctttgctggagggagaagcggtcgccaatttacagggcacaaccgagttt
gagattatcacagccctggcctatgactactttgcctcagagcaagtagatgtggccatc
atggaagttggcatgggtggactttttgatagtaccaatgtctgtcagcccattttgaca
ggaattacaactattggcttggatcatgtggccttacttggtgacaccttggaggccata
gcagagcagaaggcaggtattatcaaacaagggatgcccttggtaacagggcgtattgct
ccagaagccttggctgtgattgaccgcattgcggaagggaaagatgcgccgagacttgcc
tacgggacagattatcaggttcgtcatcaagaaagtgtggtgacaggggaagtctttgac
tatacaagtgctgtcagacaaggtcgcttccagactagcctgcttggtttgtaccaaata
gagaatgctgggatggccatagctttacttgatactttttgtcaagaagatggtcgagag
ctagcaagcaatgactttcttggtcaagccttggaagaaacaagttggccagggcgtttg
gaaatcgtgtcaagagatcccttgatgattttggatggagcccataatccccatgctatc
aaggccttgttggtaaccttgcaagaacgttttgcggattatcataaggaaatcctcttc
acttgtatcaaaaccaaagccttggaggatatgttggacttgctgggagccatgccagat
accgagcttactctaacacattttgcggatagtcgggcgacggatgaaagcgtgctgaaa
gaggcagctaagtctagaaatctcagctaccaagattggcatgattttctagagcagaat
gtgacagataaaaaagaagagaaacaaacagttaggattgtcacaggttccttgtatttc
ttgagccaagtgagggtctatctgatggagaggaagaacgagaatggatacacaaaagat
tga
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