Sphingopyxis sp. EG6: SPYCW_2205
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Entry
SPYCW_2205 CDS
T10392
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
speg Sphingopyxis sp. EG6
Pathway
speg00300
Lysine biosynthesis
speg00550
Peptidoglycan biosynthesis
speg01100
Metabolic pathways
speg01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
speg00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SPYCW_2205
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SPYCW_2205
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SPYCW_2205
Enzymes [BR:
speg01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SPYCW_2205
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
BBB09189
UniProt:
A0A2Z5UD15
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Position
complement(2274136..2275512)
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AA seq
458 aa
AA seq
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MNPLWTARAIAAATGGEASADFTVHGVAFDSREVTTGDLFVAMRGEATDGHKFIDKAIAA
GAAGIVCETAIDHPHVRVADSAAALNALGTASRARSHGRIIGVTGSAGKTGTKEALFAAL
DRFRPGKAHRSVKSYNNHVGVPLSLARMPSTADFGVFEMGMNHAGELAELTRMVRPHVAI
VTTIAPAHMEFFGSEEAIADAKGEIFEGLEPGGTAIIPFDSPHYARLRAKAEQHAAHVIS
FGLGADADVRAVDWLPDGQGGSLVTAQVQDALLCYTIAQAGVHWVSNSLAVLAAVKAVGG
DLPAAGLAFAEMAGLAGRGARHRVPLGGGHILLIDESYNANPASMAATIGQLGSESGDRK
VAILGAMKELGPDGEAYHAGLAAPLVAAGVQFALLVGEEMAPLAKALEGRIDFEHVAAHS
DAAARLGDVIHPGDTVLIKGSNSVGLSHLVTALTNGDC
NT seq
1377 nt
NT seq
+upstream
nt +downstream
nt
atgaacccgctgtggaccgcccgcgccatcgccgccgcgaccggcggcgaagcgagcgcc
gatttcaccgtgcatggcgtcgcctttgattcgcgcgaggttacgaccggcgacctcttc
gtcgcgatgcgcggcgaggcgaccgacgggcacaagtttatcgacaaagcgattgccgcg
ggcgcagcgggcatcgtctgcgaaaccgccatcgaccatccgcatgtccgcgtcgccgac
agtgccgcggcgctgaatgcgctcggtaccgcatcgcgtgcgcgcagtcatggccggatt
atcggtgtcaccggatcggcaggcaagacggggaccaaggaagcgctgttcgcggcgctc
gaccgctttcgccccggcaaggcgcatcgttcggttaaaagctacaacaaccatgtcggc
gtgccgctcagcctcgcgcgcatgccctcgaccgccgatttcggggtgttcgaaatgggg
atgaaccatgccggcgagctcgccgagctgacccgcatggtccgtccgcacgtcgctatc
gtgaccacgattgccccggcgcatatggagtttttcggcagcgaagaggcgatcgccgac
gcgaagggcgagattttcgaggggctggagcccggcggtaccgcgatcatccccttcgac
agcccgcattatgcccggctgcgcgccaaggccgaacaacatgccgcgcatgtcatcagc
ttcggtttgggcgccgacgccgatgtgcgcgcagtcgactggctgcccgacggccagggc
gggtcgctggtcaccgcacaggtgcaggatgcgctgctctgctacacgatcgcgcaggcc
ggggtgcattgggtgtccaattcgctcgcggtgctggcggcggtcaaggcggtcggcggc
gacctgccagctgcggggctggcctttgccgaaatggccgggctcgcgggccgcggcgcg
cgtcaccgggtgccgctgggcggcggacatatcctgctgatcgacgaaagctataacgcc
aaccccgcctcgatggccgcgacaatcggacagctcggcagcgaatccggtgaccgcaag
gttgcgattctcggcgcgatgaaggagctcggtccggatggcgaggcctatcatgccggg
cttgcggctccgctcgtcgcagccggggtgcaattcgccctgcttgtcggcgaagagatg
gcgccgctcgccaaagcgcttgaggggcgcatcgatttcgaacatgtggccgcccactct
gacgcagcggcacggctgggcgacgtgatccaccccggcgacaccgtgctgatcaagggg
tcgaacagcgtcggcttgtcgcatctggtgaccgcgctgaccaacggggactgttga
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