Streptococcus periodonticum: EHW89_06490
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Entry
EHW89_06490 CDS
T06568
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
spei
Streptococcus periodonticum
Pathway
spei00300
Lysine biosynthesis
spei00550
Peptidoglycan biosynthesis
spei01100
Metabolic pathways
spei01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
spei00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
EHW89_06490
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
EHW89_06490
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
EHW89_06490
Enzymes [BR:
spei01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
EHW89_06490
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF7687
Motif
Other DBs
NCBI-ProteinID:
AZQ42126
UniProt:
A0A3S9MSF9
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All DBs
Position
complement(1336192..1337562)
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AA seq
456 aa
AA seq
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MQLTFYEVASVLKAQNDVHQFSDCTFGKAEFDSRLIGEGDLFVPLKGARDGHDFIVTAFE
NGAVATLSEKELDDYPYILVDNVLAALQRLAQYYLEKMKVDVFAVTGSNGKTTTKDMLAH
LLSTTYKTYKTQGNYNNEIGLPYTVLHMPDDTEKLVLEMGQDHMGDIHLLSTIAQPKVGI
VTLIGEAHLEFFKSRYEIAKGKMQIVDGMKDGALLVVPADKIINDFLPSQLNVVRFGPDE
DIFLTKLEERKDSLTFETNFLDNAIDLPVTGKYNATNAMIAAYVALKEGVTQDKIQKAFA
TLELTRNRTEWKKAKNGADILSDVYNANPTAMRLILETFSTIPFNEKGRKLVVLADMKEL
GADSKQMHGAMITSLNPEILSEIFLYGEDMAALFAYAKEIFPPGKAHYFVKNAEKDQFSD
LVKAVKEALKPMDQLLIKGSNSMNLASLVEELENEG
NT seq
1371 nt
NT seq
+upstream
nt +downstream
nt
atgcaattaacgttctatgaagtagcttctgtattgaaagcacaaaatgatgttcatcaa
ttttcagattgtacatttggaaaggcagaatttgacagtcgattgattggagagggagac
ttgtttgttcctcttaaaggagcacgtgacgggcacgattttattgtgacggcatttgaa
aatggtgctgtggcaaccttgtcagaaaaagaattggacgactatccttatattttagtt
gataatgtgttggcagcattgcagcgtttggcacagtattatctggaaaaaatgaaggta
gatgtctttgcagttacgggttctaacggtaagacgacgaccaaagatatgctggctcac
ctcttgtcaacaacttacaagacttataaaacgcaaggaaactacaataatgaaattggt
cttccttatacggttttacacatgccagatgacaccgaaaaattggttttggaaatgggg
caagatcacatgggggatattcaccttctgtccacaattgcgcagccaaaagtaggtatt
gtgacgctgattggcgaagcgcatttagaattctttaaaagtcgttatgaaattgcaaaa
ggaaaaatgcaaattgtcgacggcatgaaagacggggctcttttggttgttccagcggac
aagattattaatgattttctaccgagccagctaaatgtagtccgttttggtccagacgaa
gatattttcctaacgaaattagaagaacgaaaagatagtttgacttttgaaaccaatttc
ttagataacgccattgaccttccagtaactgggaaatacaatgcaacaaatgccatgatt
gcagcttatgtggcattgaaagaaggagtaacacaagataagatccaaaaagcatttgca
acgcttgaattaacacgaaatcgcaccgagtggaagaaagctaaaaatggtgcggatatc
ctttcagatgtttacaatgccaatccaaccgctatgcgattgattttagagacattttca
acgattccgtttaatgaaaaaggtcggaaactagtagttttagctgatatgaaagaattg
ggggctgattctaaacaaatgcacggtgccatgataaccagcctaaatccagaaattctc
tcagaaattttcctttatggagaggacatggctgctctatttgcctatgctaaggaaatt
ttcccgcctggaaaagcccattattttgtaaaaaatgctgaaaaagatcaattttctgac
ttagtaaaggctgttaaagaagcactcaaaccaatggatcaattactaataaaaggaagt
aactctatgaacttagctagtttagtggaggaattggagaatgaagggtaa
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