Thiospirochaeta perfilievii: EW093_02625
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Entry
EW093_02625 CDS
T06210
Symbol
gshB
Name
(GenBank) bifunctional glutamate--cysteine ligase GshA/glutathione synthetase GshB
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
sper
Thiospirochaeta perfilievii
Pathway
sper00270
Cysteine and methionine metabolism
sper00480
Glutathione metabolism
sper01100
Metabolic pathways
sper01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sper00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
EW093_02625 (gshB)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
EW093_02625 (gshB)
Enzymes [BR:
sper01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
EW093_02625 (gshB)
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GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
RimK
ATPgrasp_ST
Dala_Dala_lig_C
GARS_A
Motif
Other DBs
NCBI-ProteinID:
QEN03638
UniProt:
A0A5C1Q8F4
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Position
576371..578674
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AA seq
767 aa
AA seq
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MENVLNAIINNGLERELICGVWGLEKENIRVDSNGKLALTQHPLGLGNKIEHPYITTDFS
ESQVEVITPPCKSMDEAYFMLENLHDIVTENLEKDEYLWPSSMPPIIPKDEDIPIANYGN
SSEAKDKMEYRNYIAKKYGKHKQLISGIHYNFSFNEDFLKKLHVLSSVNESFYDFKNGIY
LTAARNLLKHQWLLTYLLGANVATHSSYKHCCNKDRENIKEEVLFKGACSYRNSLCGYRN
KEDFRVSFDTLEENIRDLKNLISQGHLRGVKEYYSPVRLKNSKDTDTFEALERDGIEYIE
LRMIDLNPLSKVGIFREDLSLVHLFILSSLLYPCSSYNHKEQKKAMENQNEVSFNGHNLS
KELRDEGLFFFDRMEKVLDKLSIDCGYYNDIIRAAKRKLSHKEELYSYKVYNLVLNEGYI
NHHLSISKENKKISLNESYSLKGYEDLELSTQILLKEALLKGLRVEVLDKRENFISISNK
RKIEYIKQATKTSLDSYSTALIMENKAITKKVLLKSGISVPNGGIYTGIDRALMDFNKYL
KSKIVIKPNNTNFGIGITILEANFSIEQYQEGLELAFNNDDTILIEEFFKGNEYRFTIID
GKVAGILQRVPANVVGDGKSNILELIEIKNRNPLRGRGYKKPLEQLKVGSEELFYLKSKN
LTPNYIPQKDEIVFLRENSNISTGGDSLDFTDLIDTSYKDEAERAAKAVGANITGVDMMI
ENIQNRRSDTNATIIELNFNPAIHIHCYPFKGKNRRLGLQVLNALGF
NT seq
2304 nt
NT seq
+upstream
nt +downstream
nt
atggaaaatgtattaaatgctatcataaataacggcctagaacgggaacttatctgtgga
gtttggggccttgaaaaagagaatataagagttgatagcaatggaaaattagcactaaca
caacacccattagggttgggaaataagatagaacatccatatataacaacagatttttct
gagagccaggttgaagttataactcctccctgtaaatctatggatgaagcctattttatg
cttgaaaatttacacgatattgtaactgaaaacctagaaaaagatgagtacctttggcct
agtagtatgccacctataatacctaaagatgaggatattcctattgcaaactacggtaat
tctagtgaagcaaaagataaaatggagtataggaactatatagctaaaaaatatggcaaa
cataaacagctaataagtggaatccactacaacttctcttttaacgaagattttcttaag
aaacttcatgttttaagtagtgttaatgagtctttttatgattttaaaaatggaatatac
cttacagcagcacgtaatttattaaaacatcaatggcttttaacatatcttttaggggca
aatgtagcaactcactcatcatataaacactgttgtaataaggatagagaaaatattaag
gaagaggttctatttaaaggtgcgtgttcatacagaaatagtctctgtggttatagaaac
aaagaggattttagggtctcctttgatactttagaagagaatattagagacttaaaaaac
ctaatatcccaggggcacctacggggagttaaagagtattatagccctgtaaggttaaag
aacagtaaggatactgatacttttgaagctctagaaagggatgggattgagtatatagag
ttaagaatgattgatttaaaccctctatctaaggtgggtatttttagggaagatctatcc
cttgttcacctctttatactttctagtctgctctacccatgtagtagttataaccataaa
gaacagaaaaaagcgatggaaaatcagaatgaagttagttttaatggtcataatctgtct
aaagagttaagggatgaggggttattcttttttgatagaatggagaaagtcttagataaa
ctctctatcgattgtggttactataatgatattattagggctgcgaagagaaaactatcc
cataaagaggagttatactcttataaggtttataatcttgttttaaatgaaggttatata
aatcaccatctctcaatctctaaagagaataaaaagataagtctaaatgagagttactct
ttaaaggggtacgaagaccttgaactatcaactcagatactactaaaagaggcgctatta
aaggggcttagggttgaagtattagataagagagagaattttatatcaattagcaataaa
agaaagatagagtatattaagcaagctactaaaacatcactagacagttactctactgcc
ttaataatggaaaataaagcgattactaaaaaagtactacttaaaagtggtatatctgtt
ccaaacggtggtatatatacaggtatagatagagcattaatggattttaataagtattta
aagagtaaaattgtaattaaaccaaacaatacaaacttcggaataggtataaccatatta
gaagcaaacttctcaatagagcagtaccaagagggtctagagttggcctttaataatgat
gatacaattctaattgaagagttttttaaaggaaatgagtataggttcacaataatcgat
ggaaaagttgcaggaatacttcaaagggtcccagccaatgtagttggagatgggaagtca
aatattttagaacttatagagattaaaaatagaaacccacttagaggaagaggatataaa
aaacccctagagcagttaaaagttggaagtgaagagttattctatttaaagagtaaaaat
ttaacccctaattacataccccaaaaggatgaaatagtttttttaagggagaattccaac
attagtacaggtggtgatagtctagattttacagatttaattgatactagttacaaggat
gaagcagagagggcggccaaggcggttggagcaaatataacaggtgtagatatgatgatt
gaaaatatacaaaacagaagatcagatacaaatgcaactataattgaactaaactttaac
cctgcaatccatatacactgttacccttttaaaggaaaaaatagacggttaggactgcag
gtattaaatgcccttggcttctaa
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