Streptomyces peucetius subsp. caesius: CGZ69_20225
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Entry
CGZ69_20225 CDS
T07792
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
speu
Streptomyces peucetius subsp. caesius
Pathway
speu00860
Porphyrin metabolism
speu01100
Metabolic pathways
speu01110
Biosynthesis of secondary metabolites
speu01120
Microbial metabolism in diverse environments
speu01240
Biosynthesis of cofactors
Module
speu_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
speu_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
speu_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
speu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
CGZ69_20225
Enzymes [BR:
speu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
CGZ69_20225
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
CGZ69_20225
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Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
ATW49862
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Position
4427502..4429169
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AA seq
555 aa
AA seq
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MSPTTSNHPPLPAHGQGHVTFLGAGPGDPGLLTLRAVEALAGADVLIAEPHVLDVVRGHA
RASVSTPELTVVDDASTSAGIPVLRDAVNLVMEAARGGKRVVRAVTGDPGLDNDAGQEML
ACAAAGIPFEVVPGVAAAVGVPAYAGVPLRDEHGTDVRFIDARTASDRCWTEVGASDGTA
VVSTTLETVAAAAGELVAAGRKPDTPLTVTVAGTTTRQRTWTATLGTIAQTLKQAKVLPS
PEGQQPVIAVVGERSAAAQRDQLAWFESKPLFGWKVLVPRTKEQAASLSDQLRSYGAVPH
EVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGIK
VAAVGEQTAAALVDFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATET
LVAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSSSTVRNLVGIAGKP
HNVTVIACIGPATAKTAEEHGLRVDVLSPEPSVHRLAEALADFGAARRAAAVEAGEHVTR
PSERRPGGRRRRTTT
NT seq
1668 nt
NT seq
+upstream
nt +downstream
nt
ttgagccccaccacctcgaaccatccgccccttccggcacacggacaagggcacgtcacc
ttcctgggtgccggtcccggcgatcccggtctgctgactctgcgcgccgtcgaggcgctc
gccggagccgacgtgctgatcgccgagccccatgtgctcgacgtcgttcgcggccatgcg
cgggcgagcgtgagcacgcccgaactgacggttgttgacgatgcgtcaacatccgccggg
atccccgtactcagggatgcggtcaatcttgtcatggaggccgcgcggggcggcaagcgg
gtcgtgcgtgcggtgaccggcgacccgggtctcgacaacgacgcaggtcaggagatgctc
gcctgcgccgcggcggggatccccttcgaggtcgtgccgggcgtggccgccgcggtgggc
gtgcccgcgtacgcgggtgtcccgctccgcgacgagcacggcacggacgtccggttcatc
gacgcgcggacagcttccgaccggtgctggaccgaggtcggtgcgagtgacggcacggcc
gtcgtctccaccacactggagacggtcgccgcggcagccggtgaactggtcgccgccggc
cgcaagccggacaccccgctgacggtcaccgtcgccggtacgacgacccggcagcggacc
tggacggcgacgctcggcacgatcgcgcagaccctgaagcaggcgaaggtgctgccgtcc
cccgaaggacaacagccggtcatagccgtggtcggtgagcgcagtgccgccgcacagcgc
gaccagctcgcgtggttcgaatccaagccgctgttcggctggaaggtgctcgtgccgcgc
acgaaggagcaggccgcctcgctctccgaccagctccgttcctacggcgcggtgccgcac
gaggtcccgaccatcgccgtcgaaccgccgcgcacgccccagcagatggagcgcgcggtc
aagggcctcgtcaccggccgctacgagtggatcgccttcacctcggtcaacgcggtcaag
gccgtgcgggagaagttcgaggagtacgggctcgacgcgcgtgccttcgccgggatcaag
gtcgcggcggtcggcgagcagacggcggcggcgctcgtcgacttcggtgtgaagccggac
ctcgtgccgagcggtgagcagtccgcggccggtctgctggaggactggccgccctacgac
ccggtcttcgacccgatcgaccgcgtcttcctgccgcgcgccgacatcgccaccgagacc
ctggtcgcgggcctcatcgagctgggctgggaggtcgacgacgtcaccgcctaccggacc
gtgcgggcctcgccgccgccggcggagacgcgcgaggcgatcaagggcggcggcttcgac
gcggtgctcttcacctcgtcgtcgaccgtgcggaacctggtcggtatcgccggcaagccg
cacaacgtcaccgtgatcgcctgcatcggtccggcgaccgcgaagaccgcggaggagcac
gggctgcgggtggacgtcctgtccccggagccgtccgtgcaccggctggccgaggccctc
gccgacttcggcgcggcgcggcgggcggcggcggtcgaggcgggcgagcatgtgacgcgg
ccgtcggagcggcgtcctggcggacggcggcgtcggacgacgacctga
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