Streptococcus pyogenes Manfredo (serotype M5): SpyM50871
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Entry
SpyM50871 CDS
T00497
Symbol
fhs1
Name
(GenBank) formate--tetrahydrofolate ligase 1
KO
K01938
formate--tetrahydrofolate ligase [EC:
6.3.4.3
]
Organism
spf
Streptococcus pyogenes Manfredo (serotype M5)
Pathway
spf00670
One carbon pool by folate
spf00720
Other carbon fixation pathways
spf01100
Metabolic pathways
spf01120
Microbial metabolism in diverse environments
spf01200
Carbon metabolism
spf01240
Biosynthesis of cofactors
Module
spf_M00140
C1-unit interconversion, prokaryotes
Brite
KEGG Orthology (KO) [BR:
spf00001
]
09100 Metabolism
09102 Energy metabolism
00720 Other carbon fixation pathways
SpyM50871 (fhs1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
SpyM50871 (fhs1)
Enzymes [BR:
spf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.3 formate---tetrahydrofolate ligase
SpyM50871 (fhs1)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
FTHFS
CbiA
DUF719
Motif
Other DBs
NCBI-ProteinID:
CAM30199
UniProt:
A2REC4
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All DBs
Position
875539..877209
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AA seq
556 aa
AA seq
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MKSDIEIAQSVALQPITDIVKKVGIDGDDIELYGKYKAKLSFEKMKAVEANEPGKLILVT
AINPTPAGEGKSTMSIGLADALNQMGKKTMLALREPSLGPVMGIKGGAAGGGYAQVLPME
DINLHFTGDMHAITTANNALSALIDNHLQQGNDLGIDPRRIIWKRVLDLNDRALRQVIVG
LGSPVNGVPREDGFDITVASEIMAILCLATDLKDLKKRLADIVVAYTYDRKPVYVRDLKV
EGALTLILKDAIKPNLVQTIYGTPALIHGGPFANIAHGCNSVLATSTALRLADYTVTEAG
FGADLGAEKFLNIKVPNLPKAPDAIVIVATLRALKMHGGVAKSDLAAENCEAVRLGFANL
KRHVENMRQFKVPVVVAINEFVADTEAEIATLKALCEEIKVPVELASVWANGAEGGLALA
KTVVRVIDQEAADYKRLYSDEDTLEEKVINIVTQIYGGKAVQFGPKAKTQLKQFAEFGWD
KLPVCMAKTQYSFSDNPSLLGAPTDFDITIREFVPKTGAGFIVGLTGDVMTMPGLPKVPA
AMAMDVAENGTALGLF
NT seq
1671 nt
NT seq
+upstream
nt +downstream
nt
atgaaatcagatatcgaaattgcccaaagtgtcgccctacagccaatcactgacattgtt
aaaaaggttggaatagacggcgatgacattgagctttatggcaaatataaggctaaattg
tcttttgagaaaatgaaagctgtcgaagctaatgagcctggaaaattaatcttggtaact
gctattaaccctactccagcgggagaaggaaaatcaaccatgtctattggactggcagat
gccttaaatcaaatgggaaaaaaaaccatgcttgccttacgtgaaccctcccttggtcct
gttatggggattaaaggcggggcagcaggtggtggttatgcccaagtattgcctatggaa
gacattaatcttcactttactggtgacatgcatgccattacaaccgctaataatgcatta
tctgctttgattgacaatcatttgcagcaaggaaacgatttaggaattgatcctcgccgc
attatttggaagcgcgtgttggaccttaatgatcgtgctcttcgtcaggtaattgttggc
ttaggtagtccagtgaatggtgtgccacgcgaagatgggtttgatatcacagtagcttct
gaaatcatggcaattttatgtttggcaactgacttgaaagatctaaagaaacgtcttgct
gatatcgtcgtggcttatacctatgatcgtaagcctgtctatgtgcgtgacttgaaggtt
gaaggagcattgacattaattctaaaagatgctatcaagccaaacttggtgcagactatt
tatggaacaccagctcttattcatggggggccatttgctaatattgctcatggttgtaat
tctgtccttgctacctcaacagctttgcgattagcagattacactgttaccgaagcagga
ttcggggccgacctaggagctgaaaaattcctaaatatcaaagtacctaatcttcctaaa
gcaccagatgctatcgtcattgttgcaaccttgcgcgcccttaaaatgcatggaggtgtc
gccaaatcagatttagccgctgaaaattgtgaggctgttcgcttaggatttgccaactta
aaacgtcacgtggaaaacatgcgccaattcaaagttccagttgtggtggctatcaatgaa
tttgtagcagataccgaggctgaaattgctaccttaaaagcgctttgtgaagagattaag
gttccagtagaattagccagtgtttgggcaaatggagctgagggaggcttagcattagct
aaaacagtggttcgtgtgattgatcaagaagctgctgactacaaacgtctctattcagat
gaggatactttggaagaaaaagtgatcaatatcgttacccagatttatggtggcaaagct
gttcaatttggccccaaggccaaaacacaattgaagcagttcgcagaattcggttgggat
aaattgcctgtttgtatggctaagacccaatacagtttctcagataacccatccttgctt
ggagcgccaaccgattttgatattaccattcgtgaatttgttcctaaaacaggggcaggt
tttattgttggtttaacaggtgatgtgatgaccatgcctggtttgcctaaagttccagct
gccatggcaatggacgtagcagaaaatggcacagccctcggtctcttttag
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