Streptococcus pyogenes Manfredo (serotype M5): SpyM51732
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Entry
SpyM51732 CDS
T00497
Symbol
fhs2
Name
(GenBank) putative formate--tetrahydrofolate ligase 2
KO
K01938
formate--tetrahydrofolate ligase [EC:
6.3.4.3
]
Organism
spf
Streptococcus pyogenes Manfredo (serotype M5)
Pathway
spf00670
One carbon pool by folate
spf00720
Other carbon fixation pathways
spf01100
Metabolic pathways
spf01120
Microbial metabolism in diverse environments
spf01200
Carbon metabolism
spf01240
Biosynthesis of cofactors
Module
spf_M00140
C1-unit interconversion, prokaryotes
Brite
KEGG Orthology (KO) [BR:
spf00001
]
09100 Metabolism
09102 Energy metabolism
00720 Other carbon fixation pathways
SpyM51732 (fhs2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
SpyM51732 (fhs2)
Enzymes [BR:
spf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.3 formate---tetrahydrofolate ligase
SpyM51732 (fhs2)
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Gene cluster
GFIT
Motif
Pfam:
FTHFS
CbiA
Motif
Other DBs
NCBI-ProteinID:
CAM31054
UniProt:
A2RGS2
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All DBs
Position
1725604..1727277
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AA seq
557 aa
AA seq
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MVLSDIEIANSVTMEPISKVADQLGIDKEALCLYGKYKAKIDARQLVALKDKPDGKLILV
TAISPTPAGEGKTTTSVGLVDALSAIGKKAVIALREPSLGPVFGVKGGAAGGGHAQVVPM
EDINLHFTGDFHAIGVANNLLAALIDNHIHHGNSLGIDSRRITWKRVVDMNDRQLRHIVD
GLQGKVNGVPREDGYDITVASEIMAILCLSENISDLKARLEKIIIGYNFQGEPVTAKDLK
AGGALAALLKDAIHPNLVQTLEHTPALIHGGPFANIAHGCNSVLATKLALKYGDYAVTEA
GFGADLGAEKFIDIKCRMSGLRPAAVVLVATIRALKMHGGVPKADLATENVQAVVDGLPN
LDKHLANIQDVYGLPVVVAINKFPLDTDAELQAVYDACDKRGVDVVISDVWANGGAGGRE
LAEKVVALAEQDNQFRFVYEEDDSIETKLTKIVTKVYGGKGIKLTPTAKRELAELERLGF
GNYPICMAKTQYSFSDDAKKLGAPTDFIVTISNLKVSAGAGFIVALTGAIMTMPGLPKVP
ASETIDIDEEGNITGLF
NT seq
1674 nt
NT seq
+upstream
nt +downstream
nt
atggttttatcagatattgaaatagccaactctgtcactatggaacctatcagtaaggtt
gccgatcaattagggattgacaaggaagcgctctgtctctatggtaagtacaaggcaaaa
attgatgcccgtcaactggtcgccttaaaagacaaacctgatggcaaactcattcttgtc
actgctatctcaccaacaccagctggtgagggcaaaaccaccacttctgttggattggta
gatgctctttctgccattggaaaaaaagcagttattgcccttcgtgaaccttctcttggt
cctgtttttggggttaagggaggagctgctggcggtggccacgcgcaagttgtcccaatg
gaagacatcaaccttcactttacaggggactttcatgccatcggtgtcgccaacaactta
ttagctgccttgattgataaccacattcaccatggcaatagcctaggcattgattctaga
cgtatcacttggaaacgtgtggtggatatgaatgaccgccagcttcgtcatattgttgac
ggcttgcaaggcaaggtcaacggggtccctcgtgaagatggttatgacattaccgtcgcc
tctgaaatcatggcaatcctgtgcctatccgaaaatatttctgacctcaaagcccgcctt
gaaaaaattatcatcggttacaacttccaaggtgaacctgtaacagctaaagacttgaaa
gctggtggtgccctagcagcactgctcaaggatgcgattcatcctaatctcgtgcaaacc
ctggaacacacaccagccctcattcacggtggcccatttgctaatatcgcccatggctgt
aatagtgtcctagccaccaaactagccttgaaatatggcgattatgccgttaccgaagct
ggatttggtgctgaccttggagctgaaaaattcattgacatcaaatgccgcatgtcaggc
cttcgtccagcagccgttgtcctagtagccactattcgtgcccttaaaatgcatgggggt
gtgccaaaagcagacctggctactgaaaatgttcaggccgttgtggatggtttacctaac
cttgacaaacatttggctaatatccaagacgtctatggtcttccagttgtcgtggcgatc
aataaattcccgcttgataccgatgccgaattacaagctgtctatgatgcctgcgacaaa
cgtggcgttgatgttgtgatttctgacgtttgggcgaatggcggagctggtggccgtgaa
ctggctgaaaaagtagtagcattggcagaacaagacaatcaattccgctttgtttatgag
gaagacgatagcattgaaaccaaactgactaaaatcgttaccaaggtttacggtggtaag
ggtatcaaattgacccccacagccaaacgtgaactggcagaattagaacgcctcggcttt
ggcaactacccaatttgcatggccaaaacccagtattccttctcagacgatgccaaaaaa
cttggcgcaccaactgactttatagtgactattagcaaccttaaagtgtccgcaggagca
ggatttatcgttgccctgacaggtgctatcatgaccatgcctggccttccaaaagtacct
gccagcgaaacaattgatattgacgaggagggcaacatcacaggactattctaa
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