Streptococcus pyogenes MGAS315 (serotype M3): SpyM3_0020
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Entry
SpyM3_0020 CDS
T00089
Symbol
purL
Name
(GenBank) putative phosphoribosylformylglycinamidine synthase II
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
spg
Streptococcus pyogenes MGAS315 (serotype M3)
Pathway
spg00230
Purine metabolism
spg01100
Metabolic pathways
spg01110
Biosynthesis of secondary metabolites
Module
spg_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
spg00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
SpyM3_0020 (purL)
Enzymes [BR:
spg01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
SpyM3_0020 (purL)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
GATase_3
FGAR-AT_PurM_N-like
DJ-1_PfpI
GATase
Motif
Other DBs
NCBI-ProteinID:
AAM78627
UniProt:
A0A0H2USZ7
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All DBs
Position
36942..40598
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AA seq
1218 aa
AA seq
DB search
MTHNLQLTSLKDLRIVQVYDVFNLAEDLLARAEKHIFSEQVTDRLLTEAEITAELDKVAF
FAIEALPGQFDQRAASSQEALLLFGSDSQVKVNTAQLYLVNKDIAEAELEAVKNYLLNPV
DSRFKDITLPLEEQAFSVSDKTIPNLDFFENYKADDFAAYKADQGLAMEVDDLLFIQDYF
KSIGRVPTETELKVLDTYWSDHCRHTTFETELKNIDFSASKFQKQLQTTYDKYIAMRDEL
GRSEKPQTLMDMATIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNE
THNHPTEIEPFGGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITTPIAETRTGKLPQQV
ISKTAAHGYSSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAHKENVVREKPEAGDV
VILLGGKTGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRDGEVTRLIK
KSNDFGAGGVCVAIGELADGLEIDLDKVPLKYQGLNGTEIAISESQERMSVVVRPNDVDA
FIAACNKENIDAVVVATVTEKPNLVMTWNGETIVDLERRFLDTNGVRVVVDVKFVDKDLT
VPEARTTSAETLEADTLKVLSDLNHASQKGLQTIFDSSVGRSTVNHPIGGRYQITPTESS
VQKLPVQHGVTTTASVMAQGYNPYIAEWSPYHGAAYAVIEATARLVATGADWSRARFSYQ
EYFERMDKQAERFGQPVSALLGSIEAQIQLGLPSIGGKDSMSGTFEDLTVPPTLVAFGVT
TADSRKVLSPEFKVAGENIYYIPGQAISEDIDFDLIKANFSQFEAIQAQHKITAASAAKY
GGVLESLALMTFGNRIGASVEIAELDSSLTAQLGGFVFTSAEEIADAVKIGQTQADFTVT
VNGNDLAGASLLAAFEGKLEEVYPTEFEQADALEEVPAVVSDTVIKAKETIEKPVVYIPV
FPGTNSEYDSAKAFEQVGASVNLVPFVTLNEVAIAESVDTMVANIAKANIIFFAGGFSAA
DEPDGSAKFIVNILLNEKVRAAIDNFIEKGGLIIGICNGFQALVKSGLLPYGNFEEAGET
SPTLFYNDANQHVAKMVETRIANTNSPWLAGVEVGDIHAIPVSHGEGKFVVSASEFAELR
DNGQIWSQYVDFDGQPSMDSKYNPNGSVNAIEGITSKNGQIIGKMGHSERWEDGLFQNIP
GNKDQTLFASAVKYFTGK
NT seq
3657 nt
NT seq
+upstream
nt +downstream
nt
ttgacacataatctacaactgacttctttgaaggacttgcgtattgtgcaggtctatgat
gtcttcaatttggctgaggatttactggcgcgtgctgagaagcatattttctctgagcag
gtgacagaccgtcttttgacggaagctgaaatcactgcggagcttgataaggttgccttc
tttgccattgaggcgcttcctggtcaatttgaccaacgtgctgctagttcgcaagaagct
ttgctattatttggaagtgacagtcaggttaaggtcaatacagcccagctttacttggtc
aataaggatattgcagaagcagagcttgaagccgttaagaactatcttttgaaccctgtt
gattcgcgtttcaaggacattactttgccgcttgaagagcaggctttctctgtatctgat
aagacgatccctaatcttgatttctttgaaaattataaagctgacgattttgcggcctat
aaggcagatcagggcttggctatggaggtcgatgaccttctcttcatccaagattatttc
aaatcaatcggacgtgtgccaactgagactgagttgaaagttttggatacttactggtca
gaccactgccgtcacacaacctttgaaactgaattgaagaacattgatttttcagcttct
aaattccaaaaacaattgcagacaacttatgataaatatatcgccatgcgtgatgagctt
ggtcgttctgaaaagccacaaacacttatggatatggcgactatttttggtcgttatgag
cgtgccaacggtcgtctggacgatatggaagtctcagatgaaatcaatgcctgctcagtt
gagattgaagtagatgttgatggtgtgaaagagccttggctcctcatgtttaagaatgag
actcacaatcacccaacagaaattgagccattcggtggagcggcgacttgtatcggtggt
gctattcgtgacccattgtcagggcgttcatacgtttatcaggctatgcgtatttcaggc
gcaggcgatatcacgactccgattgcggaaacacgtactggtaaattgccacaacaggtt
atttctaagactgcggcgcacggctattcttcatatggtaaccaaattggacttgcgaca
acttatgtgcgtgagtacttccaccctggcttcgtagccaaacgcatggagcttggagct
gtggtcggagcggcacataaggaaaatgtggttcgtgaaaaaccagaagcaggtgatgtg
gtaatcttgcttggtggtaaaacagggcgtgacggtgtcggcggtgcgacaggttcatct
aaggttcaaacggttgagtctgtggaaacagctggcgcagaggtacaaaaagggaatgcc
atcgaagagcgtaagattcaacgtctcttccgtgatggtgaagtgactcgtctcatcaaa
aaatcaaacgactttggtgctggtggtgtctgtgttgccatcggtgaattggctgacggt
cttgaaatcgatttggacaaggtgcctcttaaataccaaggtcttaatggtactgaaatt
gcaatctcagaatctcaagagcgtatgtcagtcgttgttcgtccaaatgatgtggatgcc
ttcatcgcagcttgcaacaaggaaaatatcgatgccgttgtagttgcgacagttaccgag
aaaccaaatcttgtcatgacttggaatggtgaaaccatcgttgacttggaacgccgtttc
cttgataccaacggtgtccgtgtcgttgttgatgttaaattcgttgacaaggacttgaca
gttccagaagcacgcacaacatcagcagagacacttgaagcagatacgcttaaggtcttg
tctgatctcaaccatgctagtcaaaaaggtcttcaaactatctttgactcatctgttggt
cgttcaaccgttaaccacccaatcggtggtcgttaccaaatcacaccgacagaaagttct
gttcaaaaattgccagttcaacatggtgtgacaacaactgcatctgttatggctcaaggt
tacaatccttatattgcagagtggtcaccttatcacggtgctgcctatgctgtcattgaa
gcgacagctcgcttggtagcaacgggtgctgactggtctcgtgcacgtttctcttaccaa
gagtactttgagcgtatggataaacaggcagagcgttttggtcagccagtatcagctctt
cttggttctattgaggctcagattcaacttggtttgccatcaatcggcggtaaggactct
atgtctggtactttcgaagacttgacagtaccaccaaccttggtagctttcggcgtgaca
acagcggacagccgcaaggttctctctcctgagtttaaagtggctggcgaaaacatttac
tatatcccaggtcaagctatttcagaagatattgattttgaccttatcaaggctaacttt
agccagtttgaagctattcaagctcaacataagattacagctgcctcagccgctaaatac
ggtggtgtcctagaaagtcttgctctcatgacttttggtaaccgtatcggtgcttctgtt
gaaattgcagagcttgacagcagcttgacagctcaactcggaggttttgtctttacatca
gctgaggaaattgctgacgcggtgaaaatcggtcaaactcaggcagactttacagtcact
gtcaatggaaatgaccttgctggcgctagccttctagcagccttcgaaggcaaattggaa
gaggtttacccaacagaattcgaacaggcagacgctcttgaagaagttcctgctgtggta
tcagatactgttatcaaggctaaggaaacaattgaaaaaccagtggtttacattcctgtc
ttccctggtaccaactcagagtatgattcagctaaggcctttgaacaggttggagctagt
gtcaacttggtaccatttgtaaccttgaatgaggttgctattgctgagtcagttgacact
atggttgctaatattgctaaggcaaatatcatcttctttgctggaggcttctcagcagcg
gatgaaccagatgggtctgctaagtttatcgtcaatatcttgcttaacgagaaggtccgc
gcagctattgacaacttcatcgaaaaaggtggccttatcatcggtatctgtaatggtttc
caagcccttgttaaatcaggtcttcttccatacggaaacttcgaagaagctggtgagaca
agtccaactctcttctataacgatgccaaccaacacgttgccaagatggttgagactcgt
atcgcaaataccaactcaccttggttggcaggagttgaggtcggcgatattcatgccatc
ccagtttcacacggtgaaggtaaatttgttgtcagcgcttctgaatttgcagagctaaga
gacaatggtcaaatctggagccaatatgtggactttgacggacaaccatctatggattct
aaatacaatccaaacggctctgtcaatgccatcgaagggattaccagcaagaatggtcaa
atcatcggtaagatgggacactcagaacgctgggaagacggactcttccaaaatattcct
ggtaacaaagaccaaaccttgtttgctagtgcagtaaaatattttacaggaaaataa
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