Streptococcus pyogenes MGAS315 (serotype M3): SpyM3_0820
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Entry
SpyM3_0820 CDS
T00089
Symbol
topA
Name
(GenBank) putative DNA topoisomerase I
KO
K03168
DNA topoisomerase I [EC:
5.6.2.1
]
Organism
spg
Streptococcus pyogenes MGAS315 (serotype M3)
Brite
KEGG Orthology (KO) [BR:
spg00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
spg03032
]
SpyM3_0820 (topA)
03400 DNA repair and recombination proteins [BR:
spg03400
]
SpyM3_0820 (topA)
Enzymes [BR:
spg01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.1 DNA topoisomerase
SpyM3_0820 (topA)
DNA replication proteins [BR:
spg03032
]
Prokaryotic type
DNA Topoisomerases
SpyM3_0820 (topA)
DNA repair and recombination proteins [BR:
spg03400
]
Prokaryotic type
DSBR (double strand breaks repair)
NHEJ (non-homologous end-joining)
SHIIR (short-homology-independent illegitimate recombination)
Facilitator
SpyM3_0820 (topA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Topoisom_bac
Zn_ribbon_Top1
Toprim
C1_2
DUF2996
Toprim_4
HypA
Motif
Other DBs
NCBI-ProteinID:
AAM79427
UniProt:
A0A0H2UUQ4
LinkDB
All DBs
Position
872539..874668
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AA seq
709 aa
AA seq
DB search
MGTKTTTKPKTGTKKSTTKKKSTAKKNLVIVESPAKAKTIEKYLGRSYKVVASVGHIRDL
KKSSMSIDFDNNYEPQYINIRGKGPLINSLKKEAKAAKKVYLASDPDREGEAISWHLSHI
LGLDPEDKNRVVFNEITKDAVKNAFVEPRQIDMNLVDSQQARRVLDRIVGYSISPILWKK
VKKGLSAGRVQSVALKLIIDRENEIKAFVPKEYWSIDGLFKKGTKKFQATFYGINGKKTK
LDNNNDVKEVLAKLTNEDFLVSKVDKKERRRNAPLPYTTSSLQQDAANKINFRTRKTMMV
AQQLYEGIHLGENGTQGLITYMRTDSTRISPVAQNDAAQFIINRFGANYSKHGNRVKNTS
GAQDAHEAIRPSSVNHTPDSIAKYLNKDQLKLYTLIWNRFVASQMTAAVFDTVKVNLEQN
GVLFVANGSQMKFDGYMAVYNDSDKNKMLPEMAEGETVKKISTSPEQHFTQPPARYSEAT
LIKTLEENGVGRPSTYAPTLEVIQRRYYVKLSAKRFEPTELGEIVNKLIVEFFPDIVDVA
FTAEMEGKLDQVEIGEEQWQHVIDQFYQPFVKELNKAESEIEKIQIKDEPAGFDCDVCGH
PMVIKLGRFGKFYACSNFPECRNTKAITKEIGVTCPVCHKGQVIERKTKKNRIFYGCDQY
PDCEFISWDLPIGRACPKSGDYLIEKKVRGGKQVMCSNETCDYKEEKIK
NT seq
2130 nt
NT seq
+upstream
nt +downstream
nt
ttgggaacaaaaactacaactaagccaaaaacgggtactaaaaagtccaccactaaaaag
aaatcaacagcgaaaaaaaatctcgttattgttgaatcacctgccaaagctaagactatt
gaaaaatatcttggacgcagttataaagttgttgcttcggtaggacatattcgtgactta
aaaaaatcgtctatgtctattgattttgataataattatgagccacaatacattaatatc
cgtggtaagggaccccttatcaattctttaaaaaaagaagccaaagctgctaaaaaagtt
tacttggcaagtgacccggaccgtgagggagaggctatttcttggcatttgtcacatatt
ctaggactcgatcctgaagataaaaaccgagtggttttcaatgaaattaccaaagatgcg
gtgaaaaatgcttttgtggaacctcgtcaaattgacatgaacttagtggattctcaacaa
gcccgtcgcgtcttggaccgtattgtaggttactccatctcacctattctttggaaaaag
gtcaaaaaaggcctttcagcaggacgtgtccagtcggttgctttaaaactcatcattgac
cgtgaaaatgaaatcaaagcctttgttccaaaggaatactggtctattgatggtcttttt
aaaaaaggaactaaaaagtttcaagcgactttttacggtattaatggcaaaaaaacaaag
cttgataataacaacgatgtcaaagaggtattagcaaagctaacaaatgaagattttctt
gtcagcaaggttgacaagaaagagcgacgtcgtaatgctcccttaccttacacaacatca
tctcttcaacaagatgctgctaataaaatcaatttcagaacgcgtaaaaccatgatggta
gcccaacaactgtatgaggggattcatttaggagaaaatggaactcaaggtttaattacc
tatatgcgtacggattctactcgtatcagtccagtagcacaaaacgatgctgctcaattt
attatcaatcgctttggagctaattattcaaaacatggtaatcgtgtcaaaaataccagt
ggtgcccaagatgctcacgaggcgattcgtccatctagtgttaatcatacgccagactct
attgccaaataccttaacaaggatcagttaaaactttatacgcttatttggaatcgtttt
gtggctagccaaatgacagcagctgtttttgataccgtaaaggtaaacttggagcaaaat
ggcgtgctttttgttgccaatggtagccaaatgaagtttgatggttacatggctgtttac
aatgattccgataaaaacaaaatgttacctgagatggcagaaggagaaacggttaaaaaa
atatcgacctctccagaacagcactttacgcagccaccagctcgttattctgaagcaact
ctgattaaaacgctagaagaaaatggtgttggacgtccatcaacttacgctccaacctta
gaagttattcaacgcagatactatgttaaattgtctgctaagcgctttgagccaactgag
cttggggaaattgtcaacaagcttattgtcgaatttttcccagatattgttgatgttgct
tttactgccgagatggaaggtaagctagatcaagttgaaattggagaagaacaatggcaa
catgttatcgatcaattctatcaaccctttgtcaaagaattgaataaggctgagtctgaa
attgaaaagattcaaatcaaagatgaaccagctggcttcgactgtgatgtttgtggtcac
ccaatggtcattaagttaggacgttttgggaaattttacgcgtgtagcaacttcccagag
tgccgtaatacaaaagccatcactaaagaaattggtgttacttgtccggtttgtcataaa
ggacaagttatcgagcgtaaaaccaaaaaaaataggatattttatggttgtgatcagtat
ccagattgtgagtttatctcgtgggatttacctattggacgtgcttgccctaagtcaggt
gactatcttattgagaaaaaagttcgtggtggcaaacaagtaatgtgtagcaatgagacc
tgtgattacaaggaagaaaaaattaaatga
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