Streptococcus pyogenes MGAS315 (serotype M3): SpyM3_1083
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Entry
SpyM3_1083 CDS
T00089
Symbol
murF
Name
(GenBank) putative D-Ala-D-Ala adding enzyme
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
spg
Streptococcus pyogenes MGAS315 (serotype M3)
Pathway
spg00550
Peptidoglycan biosynthesis
spg01100
Metabolic pathways
spg01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
spg00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SpyM3_1083 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SpyM3_1083 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SpyM3_1083 (murF)
Enzymes [BR:
spg01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SpyM3_1083 (murF)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
SpoIIAA-like
Motif
Other DBs
NCBI-ProteinID:
AAM79690
UniProt:
A0A0H2UVA4
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All DBs
Position
complement(1126840..1128207)
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AA seq
455 aa
AA seq
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MKLTLHEVAKIVDAQNNVSDLDDVPLHHIEFDSRKITKGDLFLPLKGQRNGHEFIDLAFQ
NGAVATFSEKELPGKPHLLVEDCLKAFQKLAHYYIDKMRVDVIAVTGSNGKTSTKDMIGA
VLSTTYKTYKTQGNYNNEIGLPYTVLHMPDDTEKIVLEMGQDHMGDIRLLSEIARPRIAV
LTLVGEAHLEYFGSRDKIAQGKMQIVDGMDSNGILIAPGDSIIDPYLPENQMVIRFGDHQ
ELNVTDIREEKDSLTFTTNVLATPVSLPLPGKYNATNAMVAAYVGKLLAVADEDIIEALE
SVQLTANRTEWKKAANGADILSDVYNANPTAMRLILETFANIAKNPGGKKIAVLADMKEL
GPDSVALHSQLIKQLSPDRIDQLVFYGDDIQELAQLAHEFYPEGHVQFFQKNQQEDQFED
MVRQVQQLLAPSDQILLKGSNSMGLAKLVNHLVEN
NT seq
1368 nt
NT seq
+upstream
nt +downstream
nt
atgaaattaaccttacacgaagtggctaaaatagttgacgcccaaaataatgtgtctgac
ttagacgacgttcctctgcatcacattgaatttgatagccgaaagattacaaaaggagac
ctctttttacccttaaaaggtcaaaggaatggtcatgagtttattgatttagcctttcaa
aatggagctgtcgctactttttcagaaaaagaattgccggggaaacctcaccttcttgtt
gaagactgcctaaaagcttttcaaaagctagcccattattatattgataagatgcgcgtg
gatgttattgctgtgacaggctcaaatggtaaaacttccaccaaagatatgataggagct
gtcctatcaaccacttacaaaacttacaaaacgcaaggaaattacaataatgagattggt
ttgccttacaccgttctccacatgcctgacgatacggaaaaaattgttcttgaaatggga
caagatcacatgggagatattcgtctcctctctgaaattgcaagaccccgtattgctgtt
ttaactctggtaggcgaagcccatttagaatattttgggtcacgtgacaagattgctcaa
gggaaaatgcaaattgttgatggaatggattcaaatggcattttaattgccccaggtgat
tcgattatcgatccttatcttccagaaaaccagatggtcattcgatttggcgaccaccaa
gaattgaatgttactgatattcgagaagaaaaagatagcttaacgtttacaacaaatgtg
ttagcaacacctgtgtccctacctctaccaggaaaatacaacgcgaccaatgctatggta
gcagcctatgttggcaaattgttggcagtagcagatgaggatattatcgaggcgttagag
tctgttcaactcactgctaatcgtacagaatggaaaaaagctgctaatggtgctgacatc
ttatcagatgtttacaatgccaatccgacagccatgcgcctgattttagaaacctttgct
aacatagcaaagaaccccggtggaaaaaagattgcagtgctagctgacatgaaagaatta
ggaccagattctgttgccctacattcgcagttaatcaaacaattgtcacctgatcgcatt
gaccaacttgttttttatggtgatgatattcaagagttagcccaattagcacatgagttt
tatcctgaaggacatgttcagttcttccaaaaaaatcagcaagaagatcagtttgaagac
atggtaagacaggtgcaacaattacttgctccctctgaccaaattcttttaaaagggagt
aactcaatggggctggctaaattggtcaatcatttagttgaaaattaa
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