Streptococcus pyogenes MGAS315 (serotype M3): SpyM3_1776
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Entry
SpyM3_1776 CDS
T00089
Symbol
fhs.2
Name
(GenBank) putative formate-tetrahydrofolate ligase
KO
K01938
formate--tetrahydrofolate ligase [EC:
6.3.4.3
]
Organism
spg
Streptococcus pyogenes MGAS315 (serotype M3)
Pathway
spg00670
One carbon pool by folate
spg00720
Other carbon fixation pathways
spg01100
Metabolic pathways
spg01120
Microbial metabolism in diverse environments
spg01200
Carbon metabolism
spg01240
Biosynthesis of cofactors
Module
spg_M00140
C1-unit interconversion, prokaryotes
Brite
KEGG Orthology (KO) [BR:
spg00001
]
09100 Metabolism
09102 Energy metabolism
00720 Other carbon fixation pathways
SpyM3_1776 (fhs.2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
SpyM3_1776 (fhs.2)
Enzymes [BR:
spg01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.3 formate---tetrahydrofolate ligase
SpyM3_1776 (fhs.2)
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Gene cluster
GFIT
Motif
Pfam:
FTHFS
CbiA
Motif
Other DBs
NCBI-ProteinID:
AAM80383
UniProt:
P0DF92
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All DBs
Position
1799241..1800914
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AA seq
557 aa
AA seq
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MVLSDIEIANSVTMEPISKVANQLGIDEEALCLYGKYKAKIDARQLVALKDKPDGKLILV
TAISPTPAGEGKTTTSVGLVDALSAIGKKAVIALREPSLGPVFGVKGGAAGGGHAQVVPM
EDINLHFTGDFHAIGVANNLLAALIDNHIHHGNSLGIDSRRITWKRVVDMNDRQLRHIVD
GLQGKVNGAPREDGYDITVASEIMAILCLSENISDLKARLEKIIIGYNYRGEPVTAKDLK
AGGALAALLKDAIHPNLVQTLEHTPALIHGGPFANIAHGCNSVLATKLALKYGDYAVTEA
GFGADLGAEKFIDIKCRMSGLRPAAVVLVATIRALKMHGGVPKADLATENVQAVVDGLPN
LDKHLANIQDVYGLPVVVAINKFPLDTDAELQAVYDACDKRGVDVVISDVWANGGAGARE
LAEKVVTLAEQDNQFRFVYEEDDSIETKLTKIVTKVYGGKGITLSPAAKRELADLERLGF
GNYPICMAKTQYSFSDDAKKLGAPTDFTVTISNLKVSAGAGFIVALTGAIMTMPGLPKVP
ASETIDIDEEGNITGLF
NT seq
1674 nt
NT seq
+upstream
nt +downstream
nt
atggttttatcagatattgaaatagccaactctgtcactatggaacctatcagtaaggtt
gccaatcaattagggattgacgaggaagcgctctgtctctatggcaagtacaaggcaaaa
attgatgcccgtcaactggtcgccttaaaagacaaacctgatggcaaactcattcttgtc
actgctatctcaccaacaccagctggtgaaggcaaaaccactacttccgttggattggta
gatgctctttctgccattggaaaaaaagcagttattgcccttcgtgaaccttctcttggt
cctgtttttggggttaagggaggagctgctggcggtggccacgcgcaagttgtcccaatg
gaagacatcaaccttcactttacaggggactttcatgccatcggtgtcgccaacaactta
ttagctgccttgattgataaccacattcaccatggcaatagcctaggcattgattccaga
cgtattacttggaaacgtgtggtggatatgaatgaccgccagcttcgtcatattgttgac
ggcttgcaaggcaaggtcaacggggcccctcgtgaggatggttacgacattaccgtcgcc
tctgaaatcatggcaatcctgtgcctatccgaaaatatttctgacctcaaagcccgcctt
gaaaaaatcatcatcggttacaactatcgaggcgaacctgtaacagctaaagacttgaaa
gctggtggtgccctagccgcactgctcaaggatgcgattcatcctaatctcgtgcaaacc
ctggaacacacaccagccctcattcacggtggcccatttgctaatatcgcccatggctgt
aatagtgtcctagccaccaaactagccttgaaatatggtgattatgccgttaccgaagct
ggatttggtgctgaccttggagctgaaaaattcattgacatcaaatgccgcatgtccggc
cttcgtccagcagccgttgtcctagtagccactattcgtgcccttaaaatgcatgggggt
gtgccaaaagcagacctggctactgaaaatgttcaggccgttgtggatggtttacctaac
cttgacaaacatttggctaatatccaagacgtctatggccttccagttgtcgtggcgatc
aataaattcccgcttgataccgatgctgaattacaagctgtctatgatgcctgcgacaaa
cgtggcgttgacgttgtgatttctgatgtttgggcaaatggcggagctggtgcccgtgaa
ttagctgaaaaagtcgtgacactagccgagcaagacaatcaattccgctttgtttatgag
gaagacgatagcattgaaaccaaactgactaaaatcgttaccaaagtttacggtggtaaa
ggcatcaccttgagcccagcagccaaacgtgaactggctgacttagaacgcctcggcttt
ggcaactacccaatttgcatggccaaaacccaatattccttctcagacgatgccaaaaaa
cttggcgcaccaactgactttacagtgactattagcaaccttaaagtgtccgcaggagca
ggatttatcgttgctctgacgggtgctatcatgaccatgcctggccttccaaaagtacct
gccagcgaaaccattgatattgacgaggagggcaacatcacaggactattctaa
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