Streptococcus pyogenes MGAS10270 (serotype M2): MGAS10270_Spy0023
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Entry
MGAS10270_Spy0023 CDS
T00355
Name
(GenBank) Phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
sph
Streptococcus pyogenes MGAS10270 (serotype M2)
Pathway
sph00230
Purine metabolism
sph01100
Metabolic pathways
sph01110
Biosynthesis of secondary metabolites
Module
sph_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
sph00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
MGAS10270_Spy0023
Enzymes [BR:
sph01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
MGAS10270_Spy0023
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
GATase_3
FGAR-AT_PurM_N-like
DJ-1_PfpI
GATase
Motif
Other DBs
NCBI-ProteinID:
ABF33088
LinkDB
All DBs
Position
36793..40566
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AA seq
1257 aa
AA seq
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MSSYFPVAPLSDLVSYMNKRIFVEKKADFGIKSASLVKELTHNLQLTSLKALRIVQVYNV
FNLAEDLLARAEKHIFSEQVTDCLLTETEITAELDKVAFFAIEALPGQFDQRAASSQEAL
LLFGSDSQVKVNTAQLYLVNKDITEAELEAVKNYLLNPVDSRFKDITLPLEEQAFSVSDK
TIPNLDFFENYKADDFAAYKAEQGLAMEVDDLLFIQDYFKSIGRVPTETELKVLDTYWSD
HCRHTTFETELKNIDFSASKFQKQLQTTYDKYIAMRDELGRSEKPQTLMDMATIFGRYER
ANGRLDDMEVSDEINACSVEIEVDIDDVKEPWLLMFKNETHNHPTEIEPFGGAATCIGGA
IRDPLSGRSYVYQAMRISGAGDITTPIAETRAGKLSQQVISKTAAHGYSSYGNQIGLATT
YVREYFHPGFVAKRMELGAVVGAAPKENVVREEPEAGDVVVLLGGKTGRDGVGGATGSSK
VQTVESVETAGAEVQKGNAIEERKIQRLFRDGNVTRLIKKSNDFGAGGVCVAIGELADGL
EIDLDKVPLKYQGLNGTEIAISESQERMSVVVRPSDVDAFIAACNKENIDAVVVATVTEK
PNLVMTWNGEIIVDLERRFLDTNGVRVVVDAKVVDKDLTVPEARTTSAETLEADTLKVLS
DLNHASQKGLQTIFDSSVGRSTVNHPIGGRYQITPTESSVQKLPVQHGVTRTASVMAQGY
NPYIAEWSPYHGAAYAVIEATARLVATGADWSRARFSYQEYFERMDKQAERFGQPVSALL
GSIEAQIQLGLPSIGGKDSMSGTFEDLTVPPTLVAFGVTTADSRKVLSPEFKAAGENIYY
IPGQAISEDIDFDLIKDNFSQFEAIQAQHKITAASAAKYGGVLESLALMTFGNRIGASVE
IAELDSSLTAQLGGFVFTSAEEIAGAVKIGQTQADFTVTVNGNHLTGVSLLAAFEGKLEE
VYPTEFEQADALEEVPVVVSDTVIKAKETIEKPVVYIPVFPGTNSEYDSAKAFEQVGASV
NLVPFVTLNEAAITESVDTMVANIAKANIIFFAGGFSAADEPDGSAKFIVNILLNEKVRA
AIDSFIEKGGLIIGICNGFQALVKSGLLPYGNFEEAGETSPTLFYNDANQHVAKMVETRI
ANTNSPWLAGVEVGDIHAIPVSHGEGKFVVSASEFAELRDNGQIWSQYVDFNGQPSMDSK
YNPNGSVNAIEGITSKNGQIIGKMGHSERWEDGLFQNIPGNKDQTLFASAVKYFTGK
NT seq
3774 nt
NT seq
+upstream
nt +downstream
nt
atgtcctcctattttccagtcgctcccttgtcggacttggtatcttatatgaataaacgt
atttttgttgagaaaaaggctgactttggtattaaatcggctagtcttgtgaaagagttg
acgcataatctacaactgacctctttgaaggctttgcgtattgtgcaggtctataatgtc
ttcaatttggctgaggatttgctggcgcgtgctgagaagcatattttctctgagcaggtg
acagactgtcttttgacggaaactgaaatcactgcggagcttgataaggttgccttcttt
gccattgaggcgcttcctggtcaatttgaccaacgtgctgctagttcgcaagaagctttg
ctattatttggaagtgacagtcaggttaaggtcaatacagcccagctttacttggtcaat
aaggatattacagaagcagagcttgaagccgttaagaactatcttttgaaccctgttgat
tcgcgtttcaaggacattactttgccgcttgaagagcaggctttctctgtgtctgataag
acgatccctaatcttgatttctttgaaaattataaagctgacgattttgcggcctataag
gcagagcagggcttggctatggaggtcgatgaccttctcttcatccaagattatttcaaa
tcaatcggacgtgtgccaactgagactgagttgaaagttttggatacttactggtcagac
cactgccgtcacacaacctttgaaactgaattgaagaacattgatttttcagcttctaaa
ttccaaaaacaattgcagacgacttatgacaaatatatcgccatgcgtgatgagcttggc
cgttctgaaaagccacaaacacttatggatatggcgactatctttggtcgttatgagcgt
gccaacggtcgtctggacgatatggaagtctcagatgaaatcaatgcctgctcagttgag
attgaagtagatattgatgatgtgaaagagccttggctcctcatgtttaagaatgagact
cacaatcacccaacagaaattgagccattcggtggagcggcgacttgtatcggtggtgct
attcgtgacccattgtcagggcgttcatacgtttatcaggctatgcgtatttcaggcgca
ggcgatatcacgactccgattgcggaaacacgtgctggtaaattgtcacaacaagttatt
tctaaaactgcagcgcacggctattcttcatatggtaaccaaattgggcttgcgacaact
tatgtgcgtgagtacttccaccctggctttgtagccaaacgtatggagcttggagctgtg
gtcggagcggcacctaaggaaaatgtggttcgtgaagaaccagaagcaggtgatgtggtt
gtcttgcttggtggtaaaacaggtcgtgacggtgtcggtggtgcgacaggttcatctaag
gttcaaacggttgaatctgtggaaacagctggcgcagaggtacaaaaagggaatgccatt
gaagaacgtaagattcaacgtcttttccgtgatggcaatgtcactcgtctgatcaagaaa
tcaaatgacttcggtgcaggtggtgtctgtgttgccatcggtgaattggctgacggtctt
gaaatcgatttggacaaggtgcctcttaaataccaaggtcttaatggtactgaaattgca
atctcagaatctcaagagcgtatgtcagtcgttgttcgtccaagtgatgtggatgccttc
atcgcagcctgcaacaaggaaaatatcgatgcagtcgttgttgcgaccgttactgaaaaa
ccaaatcttgtcatgacttggaatggcgaaatcatcgttgatttggaacgccgtttcctt
gataccaatggtgtccgtgtcgttgttgatgctaaagtcgttgacaaggacttgacagtt
ccagaagcacgcacaacatcagcagagacacttgaagcagatacgcttaaggtcttgtct
gacctcaaccacgctagtcaaaaaggtcttcaaactatctttgactcatctgttggtcgc
tcaaccgttaaccacccaatcggtggtcgttaccaaatcacaccgacagaaagttctgtt
caaaaattgccagttcaacatggtgtgacaagaacagcatctgttatggctcaaggttac
aatccttatattgctgagtggtcaccttaccacggtgctgcctatgctgtcattgaagcg
acagctcgcttggtagcaacgggtgctgactggtctcgtgcacgtttctcttaccaagag
tactttgagcgtatggataaacaggcagagcgttttggtcagccagtatcagctcttctt
ggttctattgaggctcagattcaacttggtttgccatcaatcggcggtaaggactctatg
tctggtactttcgaagacttgacagtaccaccaaccttggtagctttcggcgtgacaaca
gcggacagccgcaaggttctctctcctgagtttaaagcggctggcgaaaacatttactat
atcccaggtcaagctatttcagaagatattgattttgaccttatcaaggataactttagc
cagtttgaagctattcaagctcaacataagattacagctgcctcagccgctaaatacggt
ggtgtcctagaaagtcttgctctcatgacttttggtaaccgtatcggtgcttctgttgaa
attgcagagcttgacagcagcttgacagctcaactcggaggttttgtctttacatcagct
gaggaaatcgctggtgcggtgaaaatcggtcaaactcaggcagactttacagtcactgtc
aatggaaatcaccttactggcgtaagccttctagcagccttcgaaggcaaattggaagag
gtttacccaacagaattcgaacaggcagacgctcttgaagaagttcctgttgtggtatca
gatactgttatcaaggctaaggaaacaattgaaaaaccagtggtttacattcctgtcttc
cctggtaccaactcagagtacgattcagctaaggcctttgaacaggttggagctagtgtc
aacttggtaccatttgtaaccttgaatgaggctgctattactgaatcagttgacacaatg
gtcgctaatattgctaaggcaaatatcatcttctttgctggaggtttctcagcagcggat
gaaccagatgggtctgctaagtttatcgtcaatatcttgcttaacgagaaggtccgcgca
gctattgacagcttcatcgaaaaaggtggccttatcatcggtatctgtaatggtttccaa
gcccttgttaaatcaggtcttcttccatacggaaacttcgaggaagctggtgagacaagt
ccaactctcttctataacgatgctaatcagcatgttgccaagatggttgagactcgtatc
gcaaataccaactcaccttggttggcaggagttgaggtcggcgatattcatgccattcca
gtttcacatggtgaaggtaaatttgttgtcagcgcttctgaatttgcagagctaagagac
aatggtcaaatctggagccaatatgtggactttaacggacaaccatctatggattctaaa
tacaatccaaacggctctgtcaatgccatcgaagggattaccagcaagaatggtcagatc
atcggtaagatgggacactcagaacgctgggaagacggactcttccaaaatatccctggt
aacaaagaccaaaccctctttgcaagtgctgtaaaatactttacaggaaaataa
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