Streptococcus pyogenes MGAS10270 (serotype M2): MGAS10270_Spy1041
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Entry
MGAS10270_Spy1041 CDS
T00355
Symbol
fhs1
Name
(GenBank) Formate--tetrahydrofolate ligase
KO
K01938
formate--tetrahydrofolate ligase [EC:
6.3.4.3
]
Organism
sph
Streptococcus pyogenes MGAS10270 (serotype M2)
Pathway
sph00670
One carbon pool by folate
sph00720
Other carbon fixation pathways
sph01100
Metabolic pathways
sph01120
Microbial metabolism in diverse environments
sph01200
Carbon metabolism
sph01240
Biosynthesis of cofactors
Module
sph_M00140
C1-unit interconversion, prokaryotes
Brite
KEGG Orthology (KO) [BR:
sph00001
]
09100 Metabolism
09102 Energy metabolism
00720 Other carbon fixation pathways
MGAS10270_Spy1041 (fhs1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
MGAS10270_Spy1041 (fhs1)
Enzymes [BR:
sph01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.3 formate---tetrahydrofolate ligase
MGAS10270_Spy1041 (fhs1)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
FTHFS
CbiA
DUF719
Motif
Other DBs
NCBI-ProteinID:
ABF34106
UniProt:
Q1JGN8
LinkDB
All DBs
Position
complement(991147..992817)
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AA seq
556 aa
AA seq
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MKSDIEIAQSVALQPITDIVKKVGIDGDDIELYGKYKAKLSFEKMKAVEANEPGKLLLVT
AINPTPAGEGKSTMSIGLADALNQMGKKTMLALREPSLGPVMGIKGGAAGGGYAQVLPME
DINLHFTGDMHAITTANNALSALIDNHLQQGNDLGIDPRRIIWKRVLDLNDRALRQVIVG
LGSPVNGVPREDGFDITVASEIMAILCLATDLKDLKKRLADIVVAYTYDRKPVYVRDLKV
EGALTLILKDAIKPNLVQTIYGTPALIHGGPFANIAHGCNSVLATSTALRLADYTVTEAG
FGADLGAEKFLNIKVPNLPKAPDAIVIVATLRALKMHGGVAKSDLAAENCEAVRLGFANL
KRHVENMRQFKVPVVVAINEFVADTEAEIATLKALCEEIKVPVELASVWANGAEGGLALA
KTVVRVIDQEAADYKRLYSDEDTLEEKVINIVTQIYGGKAVQFGPKAKTQLKQFAEFGWD
KLPVCMAKTQYSFSDNPSLLGAPTDFDITIREFVPKTGAGFIVGLTGDVMTMPGLPKVPA
AMAMDVAENGTALGLF
NT seq
1671 nt
NT seq
+upstream
nt +downstream
nt
atgaaatcagatatcgaaattgcccaaagtgtcgccttacaaccaatcactgacattgtt
aaaaaggttggaatagacggcgatgacattgagctttatggcaaatataaggctaaattg
tcttttgagaaaatgaaagctgtcgaagctaatgagcctggaaaattactcttggtaact
gctattaaccctactccagcgggagaaggaaaatcaaccatgtctattggactggcagat
gccttaaatcaaatgggaaaaaaaaccatgcttgccttacgtgaaccctcccttggtcct
gttatggggattaaaggcggggcagcaggtggtggttatgcccaagtattgcctatggaa
gacattaatcttcactttactggtgacatgcatgccattacaaccgctaataatgcatta
tctgctttgattgacaatcatttgcagcaaggaaacgatttaggaattgatcctcgccgc
attatttggaagcgcgtgttggaccttaatgatcgtgctcttcgtcaggtaattgttggc
ttaggcagtccagtgaatggtgtgccacgcgaagatgggtttgatatcacagtagcttct
gaaatcatggcaattttatgtttggcaactgacttgaaagatctaaagaaacgtcttgct
gatatcgtcgtggcttatacctatgatcgtaagcctgtctatgtgcgtgacttgaaggtt
gaaggagcattgacattaattctaaaagatgctatcaagccaaacttggtgcagactatt
tatggaacaccagctcttattcatggggggccatttgctaatattgctcatggttgtaat
tctgtccttgctacctcaacagctttgcgattagcagattacactgttaccgaagcagga
ttcggggccgacctaggagctgaaaaattcctaaatatcaaagtacctaatcttcctaaa
gcaccagatgctatcgtcattgttgcaaccttgcgcgcccttaaaatgcatggaggtgtc
gccaaatcagatttagccgctgaaaattgtgaggctgttcgcttaggatttgccaactta
aaacgtcacgtggaaaacatgcgccaattcaaagttccagttgtggtggctatcaatgaa
tttgtagcagataccgaggctgaaattgctaccttaaaagcgctttgtgaagagattaag
gttccagtagaattagccagtgtttgggcaaatggagctgagggaggcttagcattagct
aaaacagtggttcgtgtgattgatcaagaagctgctgactacaaacgtctctattcagat
gaggatactttggaagaaaaagtgatcaatatcgttacccagatttatggtggcaaagct
gttcaatttggccccaaggccaaaacacaattgaagcagttcgcagaattcggttgggat
aaattgcctgtttgtatggctaagacccaatacagtttttcagataacccatccttgctt
ggagcgccaaccgattttgatattaccattcgtgaatttgttcctaaaacaggggcaggt
tttattgttggtttaacaggtgatgtgatgaccatgcctggtttgcctaaagttccagct
gccatggcaatggacgtagcagaaaatggcacagccctcggtcttttttag
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