Streptococcus pyogenes MGAS10270 (serotype M2): MGAS10270_Spy1822
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Entry
MGAS10270_Spy1822 CDS
T00355
Symbol
pbp2A
Name
(GenBank) Multimodular transpeptidase-transglycosylase PBP 2A
KO
K12555
penicillin-binding protein 2A [EC:
2.4.99.28
3.4.16.4
]
Organism
sph
Streptococcus pyogenes MGAS10270 (serotype M2)
Pathway
sph00550
Peptidoglycan biosynthesis
sph01100
Metabolic pathways
sph01501
beta-Lactam resistance
Brite
KEGG Orthology (KO) [BR:
sph00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
MGAS10270_Spy1822 (pbp2A)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01501 beta-Lactam resistance
MGAS10270_Spy1822 (pbp2A)
09180 Brite Hierarchies
09181 Protein families: metabolism
01003 Glycosyltransferases [BR:
sph01003
]
MGAS10270_Spy1822 (pbp2A)
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
sph01011
]
MGAS10270_Spy1822 (pbp2A)
Enzymes [BR:
sph01000
]
2. Transferases
2.4 Glycosyltransferases
2.4.99 Transferring other glycosyl groups
2.4.99.28 peptidoglycan glycosyltransferase
MGAS10270_Spy1822 (pbp2A)
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.16 Serine-type carboxypeptidases
3.4.16.4 serine-type D-Ala-D-Ala carboxypeptidase
MGAS10270_Spy1822 (pbp2A)
Glycosyltransferases [BR:
sph01003
]
Polysaccharide
Bacterial polysaccharide (excluding LPS)
MGAS10270_Spy1822 (pbp2A)
Peptidoglycan biosynthesis and degradation proteins [BR:
sph01011
]
Peptidoglycan biosynthesis and degradation
Glycosyltransferase/DD-Transpeptidase (Class A PBP)
MGAS10270_Spy1822 (pbp2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Transgly
Transpeptidase
YrhK
Motif
Other DBs
NCBI-ProteinID:
ABF34887
LinkDB
All DBs
Position
complement(1774588..1776924)
Genome browser
AA seq
778 aa
AA seq
DB search
MRFLELLQKKFFPKAYQEKQFLMHQKTRLTPQHNQKQYSPNANHLDSSATKNSEQDPAIA
LQRSRAYEGSPKSRPAWLQKLEAVLPSPQHPIRRFWRRYHIGKLLMILIGTLVLLLGSYL
FYLSKTAKVSDLQDALKATTVIYDHKGEYAGSLSGQKGSYVELNAISDDLENAVIATEDR
TFYSNSGINLKRFLLAVVTAGRFGGGSTITQQLAKNAYLSQDQTIKRKAREFFLALELTK
KYSKKDILTMYLNNSYFGNGVWGVEDASQKYFGTTAANLTLDEAATLAGMLKGPEIYNPY
HSLKNATHRRDTVLGAMVDAKKITQTKAQQARAVGLKNRLADTYVGKTDDYKYPSYFDAV
ISEAIATYGLSEKDIVNNGYKVYTELDQNYQTGMQTTFNNDELFPVSAYDGSSAQAASVA
LDPKTGGVRGLIGRVNSSENPTFRSFNYATQAKRSPASTIKPLVVYAPAVASGWSIEKEL
PNTVQDFDGYQPHNYGNYESEDVPMYQALANSYNIPAVSTLNDIGIDKAFTYGKTFGLDM
SSAKKELGVALGGNVTTNPLEMAQAYAAFANNGVIHPAHLINRIENARGEVLKTFTDKAK
RVVSQSVADKMTAMMLGTFSNGTAVNANVYGYTLAGKTGTTETNFNPDLAGDQWVIGYTP
DVVISQWVGFNQTDENHYLTDSSAGTASAIFSTQASYILPYTKGSQFHVDNAYAQNGISA
VYGVNETGNQSGVDTQSIIDGLRKSAQEASQSLSKAVDQSGLRDKAQSIWKEIVDYFR
NT seq
2337 nt
NT seq
+upstream
nt +downstream
nt
atgagatttctagaacttttacaaaagaaattttttcctaaagcatatcaggaaaaacaa
ttcttaatgcatcaaaaaacgcgtttaacgccacaacacaatcaaaagcagtattcgcca
aatgccaatcatttggactcatcagctaccaaaaactcagaacaagaccctgcaatagct
ctgcaacgcagtagagcctacgaaggaagccctaaaagtcggcccgcttggttgcaaaag
ctggaagctgttttgccgtctcctcaacatccaattcggcgtttttggcgccgctatcac
atcggaaaactgctaatgattctgattggaactcttgtcttactcttaggatcatacttg
ttttacttatcaaaaacagctaaagtatctgatttacaagatgccttgaaggctacaacg
gttatttatgatcacaaaggagagtatgcaggcagtttatctggtcaaaaagggagttat
gttgagctcaacgctatttcagatgatcttgagaatgctgttattgccactgaggatagg
actttttacagtaatagcggtattaatcttaaacgcttcttattggcagtagttacggcg
ggccgctttggaggtggctcaacgattacacagcaactggctaaaaatgcttatctctca
caagatcagacaattaaacgaaaggccagagagttttttttggcgttagagttgaccaaa
aaatacagtaaaaaagatattcttactatgtaccttaacaactcctactttggaaatgga
gtttggggagttgaagatgccagtcaaaaatattttggaaccacagctgctaacttaaca
ttggatgaagctgccacattagcaggtatgctcaaaggacctgaaatatataacccttac
cattctctaaaaaatgctactcaccgtagagatactgttttaggagcgatggttgatgcc
aaaaagattacccaaacaaaagctcagcaagctagagcagtagggctaaaaaatcgctta
gctgatacttatgttggtaagacagatgactacaaatacccatcctactttgatgctgtt
attagtgaagcaatagcaacttatggtctttcagaaaaagacattgttaataatggatac
aaagtttacaccgagctagatcaaaattaccaaactggcatgcagacgacttttaacaac
gatgaactatttcctgtttcagcttatgacggtagctctgctcaagcagctagtgttgct
ttagatcctaaaacaggaggtgttagaggtctgattggtcgtgtgaatagtagtgaaaat
ccgactttcagaagttttaactatgcgactcaagcaaaacgtagtcccgcatcaacaatc
aaaccactcgtggtttacgcgccagccgttgcttcaggatggtcaattgaaaaagaacta
ccaaataccgttcaagatttcgatggctatcaaccacataattatggaaattatgaatca
gaagatgttcctatgtatcaagcattagcaaactcttataatattccagcagtttctaca
ttgaacgatatcggaatcgataaagcctttacctatggtaaaacatttgggttagatatg
agctctgccaaaaaagagttgggggtagctttaggtggcaacgtgacaaccaatccattg
gagatggctcaggcatatgctgcctttgccaataatggagtaatccatcctgcgcacttg
attaaccggattgaaaatgccaggggtgaagtgcttaaaacctttactgataaggctaaa
cgtgttgtcagccagtctgttgcagataagatgacagccatgatgctaggtaccttttca
aatggaacagcagtcaatgctaacgtatatggctatacactagctggtaaaacagggacg
acagaaaccaacttcaatcccgacttagcaggcgatcagtgggttattggttatacgcca
gatgttgttattagtcaatgggtaggatttaatcagaccgatgaaaatcattatctaacg
gattcaagtgcaggcacggcttcagctatttttagcactcaggcatcttacattttgcct
tataccaagggcagccaatttcatgtagataatgcctacgctcaaaatggtatttcagct
gtttatggagtcaatgaaacaggtaatcaatcaggagttgacactcaatctattattgat
ggtttaagaaaatcagcacaagaagcttcgcaatcactatcaaaagcagtcgatcagtca
gggttacgtgataaggcccaatctatttggaaagagattgttgactattttagatag
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