Sphingobium sp. EP60837: EP837_02176
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Entry
EP837_02176 CDS
T04432
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sphb
Sphingobium sp. EP60837
Pathway
sphb00300
Lysine biosynthesis
sphb00550
Peptidoglycan biosynthesis
sphb01100
Metabolic pathways
sphb01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sphb00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
EP837_02176 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
EP837_02176 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
EP837_02176 (murF)
Enzymes [BR:
sphb01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
EP837_02176 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
SCFA_trans
Motif
Other DBs
NCBI-ProteinID:
ANI78580
UniProt:
A0A173KXY8
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Position
1:2228373..2229749
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AA seq
458 aa
AA seq
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MSELWTSEEIAQATGGVASAPFAVSGVAFDSREVTGGDLFVAMKGETTDGHNFVEKAFGQ
GAAGSIVSEAIPQPHILVKDSVVALEALGRASRARMRGKVVGVTGSVGKTGTKEALFQAL
DRVCPGEVHRSVKSYNNHVGVPLSLSRMPRASAFGVFEMGMNHAGELAQLTQQVRPHVAI
VTAIAPAHIEFFGTEEKIAEAKAEIFEGLEPDGTAIIPYDSPHVATLYAKAEQHAARILT
FGFDEEADVRARDMVPAANGGTLVTATLPSAELCFTVSAPGEHWVSNALAVLAAVEALGG
DLAAAGLALAEMPGLPGRGERKTLPIAGGEALLIDESYNANPLSMAATLKQLGKERASRR
IAVLGGMRELGDRSRELHAGLVEPLAAGQVDYAILVGEEMKPLAEALGGVLSFDHVPDAA
AAISLIQTEMRAGDAILVKGSNGIGLSRLVAALGEHKN
NT seq
1377 nt
NT seq
+upstream
nt +downstream
nt
gtgagcgagctttggacttccgaagagatagcgcaggccacagggggcgtcgcatcggcg
cccttcgccgtttcgggcgtggcgttcgacagccgtgaagtgactggcggcgatctgttc
gtcgcgatgaagggtgagacgaccgacggccacaatttcgtggagaaagcgttcggccag
ggcgcagcaggctccatcgtcagcgaagcgatcccccagcctcacattctggtgaaggac
agcgtcgttgcgttggaggcgctgggccgcgcatcccgcgccaggatgcgcggcaaggtg
gtgggcgttaccggatcggtgggcaagaccggcaccaaggaagcgttgttccaggcgctg
gatcgcgtctgccccggcgaagtccatcgctcggtcaaaagctataataatcatgtgggc
gtgccgttgagcctgtcccgcatgccccgcgcgtcggctttcggtgtcttcgaaatgggc
atgaaccatgccggtgagctggctcaactgacccagcaagtccgcccgcatgtcgcgatc
gtgaccgccatcgcgccggctcacatcgaatttttcggcaccgaagagaagatcgcagag
gccaaggctgaaatcttcgaggggctggagccggacggaacggcgatcattccctatgac
agcccgcatgtcgccaccctctatgccaaggcggagcagcatgccgcgcgcatcctgact
ttcggcttcgatgaagaggctgacgtccgggcgcgtgatatggttccggccgcgaacggc
ggcacgttagtgacggcgaccctgcctagtgcggagctttgcttcaccgtaagcgcgccg
ggggaacattgggtgtcgaatgcgcttgccgtgctggccgcggtggaggcgttgggcggc
gatctggctgcagcgggcctcgcacttgcggagatgcccggactgcccgggcggggcgaa
cgcaagaccctgcccatcgcgggcggtgaagcgctgctcatcgatgaaagctacaacgcc
aatccgctcagcatggcggcgacgctcaagcagttgggcaaggaacgtgcaagtcgccgt
atcgcggtgctgggcggcatgcgcgagttgggcgatcgcagtcgtgaactgcatgccgga
ctggtagaaccgctggcggcggggcaggtcgattatgccatcctggtcggcgaggagatg
aagccattggccgaagcgctcggcggggttctttctttcgaccatgtgccggacgccgct
gccgccatcagtcttatacagaccgaaatgcgcgcgggcgacgcaatcctggtaaaggga
tcaaacggcatcggcctgtcgcgcttggtcgccgcgcttggggaacataagaactga
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