Sphingomonas sp. FARSPH: DM480_15340
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Entry
DM480_15340 CDS
T05685
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
sphf
Sphingomonas sp. FARSPH
Pathway
sphf00790
Folate biosynthesis
sphf01100
Metabolic pathways
sphf01240
Biosynthesis of cofactors
Module
sphf_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
sphf00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
DM480_15340
Enzymes [BR:
sphf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
DM480_15340
6.3.2.17 tetrahydrofolate synthase
DM480_15340
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
AXJ97160
UniProt:
A0A345WU08
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Position
3237248..3238555
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AA seq
435 aa
AA seq
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MPDHATSNDPAVQAQLDRLSLLSPGADVLGLDRIARLLARLGDPHRAMPPVFHVAGTNGK
GSTCAFLRAAIEATGCDVHVFSSPHLVHFNERIRVAGRLIDDASLAALLAEVLDHAEGIA
PSFFEVTTAAAFLAFARTPAAATIVEVGLGGRLDATNVVDRPAVTGIAALGLDHQAFLGD
RLTDIATEKAGIAKSGVPIITMNYPRAARDRVAAVAEAAGAPVFARNRQWWSESGRTTMR
YRDAGFALSAPRPRLVGPHQSHNFALAIAMLRHQAAVHVPEAAMRAAAQWAQWPARMQRM
GKGPLRDRLSPGSELWLDGAHNPSAAQPVARALRSLAKGRPVVLVVGMLANKDAEGVLRL
LAPTLSRAIAVPVEGHDSHAPAQLASLAEDFGVAASVAPDLASALELVAGDAVVLIAGSL
YLAGEALHLNDEAPD
NT seq
1308 nt
NT seq
+upstream
nt +downstream
nt
atgcccgatcacgcgacatccaacgatcccgccgtgcaggcgcagctcgaccgtctgtcg
ttgctttcaccgggcgccgacgtgctcggcctcgaccggatcgcacgcctgctggcgcgg
ctcggcgatccgcaccgggcgatgccaccggtcttccatgtcgcaggcacgaacggcaag
ggatcgacctgcgccttcctgcgcgccgcgatcgaggcgacgggatgcgatgtccacgtc
ttctccagcccgcacctcgtccacttcaacgaacgtatccgcgtcgccggccggctgatc
gacgacgcgagcctcgccgccctgctcgccgaggtactcgatcatgccgagggcatcgcg
cccagcttcttcgaggtgacgacggccgccgccttcctcgccttcgcgcggacgccggcc
gcggcaacgatcgtggaggtcggcctcggcgggcggctcgatgcgacgaacgtcgtcgat
cgccccgcggtcaccggcatcgccgcgctcggcctcgaccaccaggcgttcctgggcgac
cggctgacggacatcgccaccgaaaaggcgggcattgccaaatcgggcgtgccgataatc
acgatgaactatccgcgtgcggcgcgggaccgcgtcgcggcggtcgcagaggcggccggc
gcgccagtgttcgcgcgcaaccggcaatggtggagcgagagcggacgcacgacgatgcgc
tatcgcgacgcgggcttcgcgctgtccgccccccggccaaggctggtcggaccgcatcaa
tcacacaatttcgcgctggcgatcgccatgctgcgccatcaagccgcggtgcatgtgccc
gaagccgcgatgcgcgccgccgcgcaatgggcgcaatggcccgcccgcatgcagcggatg
ggcaaaggaccgctgcgcgaccgcctgtcgccgggaagcgagttgtggctcgacggcgcg
cacaatccgtcggcggcgcagcccgtcgcgcgcgccttgcgcagcctggcaaaggggcga
cccgtcgttctcgtcgtcgggatgctcgccaacaaggatgccgagggcgtgctgcggctg
ctcgcacccaccctgtcgcgggcgatcgcagtgcccgtggaaggccacgacagccacgcg
cccgcgcagctggcttcgctcgccgaggatttcggcgttgccgcgtcggttgcgccggac
ctggcgtcggcgctcgagctggtcgcgggcgatgcggtggtactgatcgccgggtcgctg
tacctcgccggcgaagcgctccatctgaacgacgaagcaccggactga
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