Streptomyces phaeoluteigriseus: NFX46_00250
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Entry
NFX46_00250 CDS
T08568
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
sphw
Streptomyces phaeoluteigriseus
Pathway
sphw00280
Valine, leucine and isoleucine degradation
sphw00640
Propanoate metabolism
sphw00785
Lipoic acid metabolism
sphw01100
Metabolic pathways
sphw01110
Biosynthesis of secondary metabolites
sphw01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
sphw00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
NFX46_00250 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
NFX46_00250 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
NFX46_00250 (pdhA)
Enzymes [BR:
sphw01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
NFX46_00250 (pdhA)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
USQ82337
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Position
51665..52798
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AA seq
377 aa
AA seq
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MTVMEQRGGYRPTPPPAWQPRTDPAPLLPDAEPYRVLGTEAAAQADPELLRRLYADLVRG
RRYNAQATALTKQGRLAVYPSSTGQEACEVAAALVLEERDWLFPSYRDTLAVVARGVDPV
EALTLLRGDWHTGYDPFEHRVAPLCTPLATQLPHAVGLAHAARLKGDDVVALAMVGDGGT
SEGDFHEALNFAAVWRAPVVFLVQNNGFAISVPLAKQTAAPSLAHKAVGYGMPGRLVDGN
DAVAVHAVLADAVRHARAGGGPTLVEAITYRVDAHTNADDATRYRGDAEVETWRGHDPID
LLERELTERGLLDEETKQAARDAAETMAADLRARMNQDAPLDPMDLFAHVYAEPTPQLRE
QRDLLRAEIEAEQGGTH
NT seq
1134 nt
NT seq
+upstream
nt +downstream
nt
atgacggtcatggagcagcggggcggataccggccgacaccgccgcccgcctggcagccc
cgcaccgaccccgcgccgctgctgcccgacgcggagccctaccgcgtcctcggcaccgag
gcggccgcacaggccgacccggagctgctgcgccggctctacgccgatctggtgcgcggc
cgtcggtacaacgcgcaggccaccgccctgaccaagcagggccgcctcgccgtctacccc
tccagcacgggccaggaggcctgtgaggtcgccgccgcgctcgtccttgaggagcgcgac
tggctcttcccgagctaccgcgacaccctcgcggtcgtcgcccgcggcgtggacccggtg
gaggccctcacactgctgcggggcgactggcacaccggctacgaccccttcgagcaccgc
gtggcccccctgtgcacgccgctcgccacccaactcccgcacgccgtggggctcgcgcac
gccgcccgcctcaagggcgacgacgtggtggcgctcgccatggtcggcgacggcggcacc
agcgagggcgacttccacgaggcgctgaacttcgccgccgtctggcgggcgccggtcgtc
ttcctcgtccagaacaacggcttcgcgatctccgtcccgctcgccaagcagaccgccgcc
ccctccctggcccacaaggccgtcgggtacggcatgccgggccggctggtcgacggcaac
gacgcggtcgccgtgcacgccgtgctggcggacgccgtacggcacgcgcgtgcgggcggc
ggtcccacgctcgtcgaggcgatcacctaccgggtggacgcccacaccaacgccgacgac
gcgacccgctaccgcggcgacgccgaggtcgagacctggcgcggacacgacccgatcgac
ctcctggagcgggagctgaccgagcgcggtctcctcgacgaggagacgaaacaggccgcc
cgggacgccgccgagaccatggccgccgacctgcgcgcccgcatgaaccaggacgctccg
ctcgaccccatggacctcttcgcccatgtgtatgccgagcccaccccgcaactgcgggag
cagcgcgacctgctgcgggccgagatcgaggcggagcaggggggaacgcactga
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