Sphingopyxis sp. PAMC25046: E5675_06555
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Entry
E5675_06555 CDS
T06315
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sphx
Sphingopyxis sp. PAMC25046
Pathway
sphx00300
Lysine biosynthesis
sphx00550
Peptidoglycan biosynthesis
sphx01100
Metabolic pathways
sphx01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sphx00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
E5675_06555
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
E5675_06555
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
E5675_06555
Enzymes [BR:
sphx01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
E5675_06555
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
QCB54124
UniProt:
A0A4P7RVJ0
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Position
1398838..1400214
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AA seq
458 aa
AA seq
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MNPLWTARAIASATDGTASADFTVQGVAFDSREVTKGDLFIAMKGETADGHAFIDKAIAA
GAAGIICETQIDHPHVRVADSAAALNALGIASRARSHGRIIGVTGSAGKTGTKEALFAAL
DRFRPGKAHRSVKSYNNHVGVPLSLARMPSTVDYGIFEMGMNHAGELAALTRIVRPHVAI
VTTIAPAHMEYFGSEEAIADAKGEIFEGLEPGGTAIVPFDSPHYARLRAKAEQHAAHLVS
FGLNEGADVRAVDWLPDGQGGSLVTAEVQDSLLCFTIAQAGAHWVANSLAVLAAVKAVGG
DLPAAGLAFAEMGGLTGRGARHRVEVPGGDILVIDESYNANPASMAATIGQLGTESAGRK
VAILGAMKELGPDGEAYHAALAAPLVAAGVQFALLVGEEMAPLAKALEGRIDFEHVAAHP
AAVGRLGDLIRAGDAVLVKGSNSVGLSHVVTALISGDY
NT seq
1377 nt
NT seq
+upstream
nt +downstream
nt
atgaacccgctctggaccgcgcgcgccatcgcctccgccacggatggcaccgccagcgcc
gacttcaccgtgcagggcgtcgcgttcgactcgcgcgaggtgacgaagggcgacctcttc
atcgcgatgaagggcgaaaccgccgacggccatgccttcatcgacaaggcgattgcggcg
ggcgccgcgggcataatctgcgaaacccaaatcgaccatccgcatgtccgcgttgccgac
agcgcggcggcgctgaatgcgctgggcatcgcatcgcgtgcgcgcagccatggccgcatc
atcggcgtcaccggttcggcgggcaagacggggacgaaggaggcgctgttcgccgcgctc
gaccgtttccgccccggcaaggcgcatcgctcggtcaaaagctacaacaatcatgtcggc
gtgccgctcagcctcgcgcgcatgccatctaccgtcgattatggcatattcgagatgggg
atgaaccacgcgggcgagcttgcagcgctgacgcggatagtgcgcccgcacgtcgccatc
gtcaccaccatcgcccccgcgcatatggaatatttcggcagcgaggaagcgatcgccgac
gcgaagggcgagattttcgaagggctcgagcccgggggcaccgcgatcgtcccgttcgac
agcccgcattatgcgcgccttcgcgccaaggccgagcagcacgccgcgcacctcgtcagc
ttcgggctgaacgagggcgccgacgtccgcgcggtcgactggctgcccgacgggcagggc
ggttcgctcgtcaccgccgaggtgcaggactcgctgctctgctttaccatcgcgcaggcc
ggcgcgcactgggtcgccaattcgctcgcggtgctcgccgcggtgaaggcggtcggcggc
gatttgcccgcagcgggcctcgccttcgccgaaatgggcggcctcacagggcgcggcgcg
cgtcaccgggtcgaagtgcccggcggcgacatcctcgtcatcgacgaaagctataacgcc
aaccccgcctcgatggcggcgacgatcggtcagctcgggaccgaatccgcaggccgcaag
gttgcgattctcggtgcgatgaaggagctcggtcccgacggcgaagcctatcacgccgcg
cttgccgctccgctcgtcgcggccggagtgcaattcgccctgcttgtcggcgaagagatg
gcgccgctcgccaaagcacttgagggccgcatcgatttcgagcatgtggccgcccacccg
gccgcggtagggcggctcggtgacctgatccgcgccggcgacgccgtgctggtcaagggg
tcgaacagcgtcggcctgtcgcatgtcgtgacggcgctgatcagtggggattattga
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