Streptococcus pyogenes MGAS10750 (serotype M4): MGAS10750_Spy0023
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Entry
MGAS10750_Spy0023 CDS
T00356
Name
(GenBank) Phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
spi
Streptococcus pyogenes MGAS10750 (serotype M4)
Pathway
spi00230
Purine metabolism
spi01100
Metabolic pathways
spi01110
Biosynthesis of secondary metabolites
Module
spi_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
spi00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
MGAS10750_Spy0023
Enzymes [BR:
spi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
MGAS10750_Spy0023
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Paralog
Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
GATase_3
FGAR-AT_PurM_N-like
DJ-1_PfpI
GATase
Motif
Other DBs
NCBI-ProteinID:
ABF36973
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Position
36758..40531
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AA seq
1257 aa
AA seq
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MSSYFPVAPLSDLVSYMNKRIFVEKKADFGIKSASLVKELTHNLQLTSLKDLRIVQVYDV
FNLAEDLLARAEKHIFSEQVTDRLLTEAEITSELDKVAFFAIEALPGQFDQRAASSQEAL
LLFGSDSQVKVNTAQLYLVNKDIAEAELEAVKNYLLNPVDSRFKDITLPLEEQAFSVSDK
TIPNLDFFENYKADDFAAYKADQGLAMEVDDLLFIQDYFKSIGRVPTETELKVLDTYWSD
HCRHTTFETELKNIDFSASKFQKQLQTTYDKYIAMRDELGRSEKPQTLMDMATIFGRYER
ANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPFGGAATCIGGA
IRDPLSGRSYVYQAMRISGAGDITTPIAETRAGKFPQQVISKTAAHGYSSYGNQIGLATT
YVREYFHPGFVAKRMELGAVVGAAPKENVVREKPEAGDVVILLGGKTGRDGVGGATGSSK
VQTVESVETAGAEVQKGNAIEERKIQRLFRDGEVTRLIKKSNDFGAGGVCVAIGELADGL
EIDLDKVPLKYQGLNGTEIAISESQERMSVVVRPSDVDAFIAACNKENIDAVVVATVTEK
PNLVMTWNGETIVDLERRFLDTNGVRVVIDAKVVDKDLTVPEARTTSAETLEADTLKVLS
DLNHASQKGLQTIFDSSVGRSTVNHPIGGRYQITPTESSVQKLPVQHGVTRTVSVMAQGY
NPYIAEWSPYHGAAYAVIEATARLVATGADWSRARFSYQEYFERMDKQAERFGQPVSALL
GSIEAQIQLGLPSIGGKDSMSGTFEDLTVPPTLVAFGVTTADSRKILSPEFKAAGENIYY
IPGQAISEDIDFDLIKANFSQFEAIQAQHKITAASAAKYGGVLESLALMTFGNRIGASVE
IAELDSSLTAQLGGFVFTSAEEIADAVKIGQTQADFTVTVNGNDLAGASLLAAFEGKFEE
VYPTEFEQADALEEVPAVVSDTVIKAKETIEKPVVYIPVFPGTNSEYDSAKAFEQVGASV
NLVPFVTLNEIAIAESVDTMVANIAKANIIFFAGGFSAADEPDGSAKFIVNILLNEKVRA
AIDSFIEKGGLIIGICNGFQALVKSGLLPYGNFEEAGETSPTLFYNDANQHVAKMVETRI
ANANSPWLAGVEVGDIHAIPVSHGEGKFVVSASEFAELRDNGQIWSQYVDFDGQPSMDSK
YNPNGSVNAIEGITSKNGQIIGKMGHSERWEDGLFQNIPGNKDQTLFASAVKYFTGK
NT seq
3774 nt
NT seq
+upstream
nt +downstream
nt
atgtcctcctattttccagtcgctcccttgtcggatttggtatcttatatgaataaacgt
atttttgttgagaaaaaggctgactttggcattaaatcggctagccttgtgaaagagttg
acacataatctacaactgacttctttgaaggacttgcgtattgtgcaggtctatgatgtc
ttcaatttggctgaggatttactggcgcgtgctgagaagcatattttctctgagcaggtg
acagaccgtcttttgacggaagctgaaatcacttcggagcttgataaggttgccttcttt
gccattgaggcgcttcctggtcaatttgaccaacgtgctgctagttcgcaagaagctttg
ctattatttggaagtgacagtcaggttaaggtcaatacagcccagctttacttggtcaat
aaggatattgcagaagcagagcttgaagccgttaagaactatcttttgaaccctgttgat
tcgcgtttcaaggacattactttgccgcttgaagagcaggctttctctgtatctgataag
acgatccctaatcttgatttctttgaaaattataaagctgacgattttgcggcctataag
gcagatcagggcttggctatggaggtcgatgaccttctcttcatccaagattatttcaaa
tcaatcggacgtgtgccaactgagactgagttgaaagttttggatacttactggtcagac
cactgccgtcacacaacctttgaaactgaattgaagaacattgatttttcagcttctaaa
ttccaaaaacaattgcagacaacttatgacaaatatatcgccatgcgtgatgagcttggt
cgttctgaaaagccacaaacacttatggatatggcgactatttttggtcgttatgagcgt
gccaacggtcgtctggacgatatggaagtctcagatgaaatcaatgcctgctcagttgag
attgaagtagatgttgatggtgtgaaagagccttggctcctcatgtttaagaacgagact
cacaatcacccaacagaaattgagccattcggtggagcggcgacttgtatcggtggtgct
attcgtgacccattgtcagggcgttcatacgtttatcaggctatgcgtatttcaggcgca
ggcgatatcacgactccgattgcggaaacacgtgctggtaaatttccacaacaagttatt
tctaaaactgcggcgcacggctattcttcatatggtaaccaaattgggcttgcgacaact
tatgtgcgtgagtacttccaccctggcttcgtagccaaacgtatggagcttggagctgtg
gtcggagcggcacctaaggaaaatgtggttcgtgaaaaaccagaagcaggtgatgtggta
atcttgcttggtggtaaaacagggcgtgacggtgtcggcggtgcgacaggttcatctaag
gttcaaacggttgagtctgtggaaacagctggcgcagaggtacaaaaagggaatgccatc
gaagagcgtaagattcaacgtctcttccgtgatggtgaagtgactcgtctcatcaaaaaa
tcaaacgactttggtgctggtggtgtctgtgttgctatcggtgaattggctgacggtctt
gaaatcgatttggacaaggtcccacttaaataccaaggtcttaatggtactgaaattgca
atctcagaatctcaagagcgtatgtcagtcgttgttcgtccaagtgatgtggatgccttc
atcgcagcttgcaacaaggaaaatatcgatgccgttgtagttgcgacagttaccgagaaa
ccaaatcttgtcatgacttggaatggtgaaaccatcgttgacttggaacgccgtttcctt
gataccaacggtgtccgtgtcgttattgatgctaaagtcgttgacaaggacttgacagtt
ccagaagcacgcacaacatcagcagagacacttgaagcagatacgcttaaggtcttgtct
gacctcaaccacgctagtcaaaaaggtcttcaaactatctttgactcatctgttggtcgc
tcaaccgttaaccacccaatcggtggtcgttaccaaatcacaccgacagaaagttctgtt
caaaaattgccagttcaacatggtgtgacaagaacagtatctgttatggctcaaggttac
aatccttatattgctgagtggtcaccttaccacggtgctgcctatgctgtcattgaagcg
acagctcgcttggtagcaacgggtgctgactggtctcgtgcacgtttctcttaccaagag
tactttgagcgtatggataaacaggcagagcgttttggtcagccagtatcagctcttctt
ggttctattgaggctcagattcaacttggtttgccatcaatcggcggtaaggactctatg
tctggtactttcgaagacttgacagtaccaccaaccttggtagctttcggtgtgacaaca
gcggacagccgcaagattctctctcctgagtttaaagcggctggcgaaaacatttactat
atcccaggtcaagctatttcagaagatattgattttgatcttatcaaggctaactttagc
cagtttgaggctattcaagctcaacataagattacagctgcctcagccgctaaatacggt
ggtgtcctagaaagtcttgctctcatgacttttggtaaccgtatcggtgcttctgttgaa
attgcagagcttgacagcagcttgacagctcaactcggaggttttgtctttacatcagct
gaggaaattgctgacgcggtgaaaatcggtcaaactcaggcagactttacagtcactgtc
aatggaaatgaccttgctggcgctagccttctagcagctttcgaaggcaaatttgaagag
gtttacccaacagaattcgaacaggcagacgctcttgaagaagttcctgctgtggtatca
gatactgttatcaaggctaaggaaacaattgaaaaaccagtggtttacattcctgtcttc
cctggtaccaactcagagtatgattcagctaaggcctttgaacaggttggagctagtgtc
aacttggtaccatttgtaaccttgaatgagattgctattgctgagtcagttgacactatg
gttgctaatattgctaaggcaaatatcatcttctttgctggaggcttctcagcagcggat
gaaccagatgggtctgctaagtttatcgtcaatatcttgcttaacgagaaggtccgcgca
gctattgacagcttcatcgaaaaaggtggccttatcattggtatctgtaatggtttccaa
gcccttgttaaatcaggtcttcttccatacggaaacttcgaggaagctggtgagacaagt
ccaactctcttctataacgatgcgaaccaacacgttgccaagatggttgagactcgtatc
gcaaatgccaactcaccttggttggcaggagttgaggtcggcgatattcacgccattcca
gtttcacacggtgaaggtaaatttgttgtcagcgcttctgaatttgcagagctaagagac
aatggtcaaatctggagccaatatgtggactttgacggacaaccatctatggattctaaa
tacaatccaaacggctctgtcaatgccatcgaagggattaccagcaagaatggtcaaatc
atcggtaagatgggacactcagaacgctgggaagacggactcttccaaaatatccctggt
aacaaagaccaaaccctctttgcaagtgctgtaaaatactttacagggaagtaa
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