Streptococcus pyogenes MGAS10750 (serotype M4): MGAS10750_Spy0027
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Entry
MGAS10750_Spy0027 CDS
T00356
Name
(GenBank) Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
spi
Streptococcus pyogenes MGAS10750 (serotype M4)
Pathway
spi00230
Purine metabolism
spi00670
One carbon pool by folate
spi01100
Metabolic pathways
spi01110
Biosynthesis of secondary metabolites
Module
spi_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
spi00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
MGAS10750_Spy0027
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
MGAS10750_Spy0027
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
spi04147
]
MGAS10750_Spy0027
Enzymes [BR:
spi01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
MGAS10750_Spy0027
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
MGAS10750_Spy0027
Exosome [BR:
spi04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
MGAS10750_Spy0027
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Motif
Other DBs
NCBI-ProteinID:
ABF36977
UniProt:
Q1J934
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All DBs
Position
44102..45649
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AA seq
515 aa
AA seq
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MTKRALISVSDKSGIIDFAKELKNLGWDIISTGGTKVALDNAGVETIAIDDVTGFPEMMD
GRVKTLHPNIHGGLLARRDVDSHLQAAKDNNIELIDLVVINLYPFKETILRPDVTYDLAV
ENIDIGGPSMLRSAAKNHASVTVVVDPADYATVLGELADAGQTTFETRQRLAAKVFRHTA
AYDALIAEYFTAQVGEAKPEKLTITYDLKQAMRYGENPQQDADFYQKALPTDYSIASAKQ
LNGKELSFNNIRDADAAIRIIRDFKDRPTVIALKHMNPCGIGQADDIETAWDYAYEADPV
SIFGGIVVLNREVDAATAKKMHPIFLEIIIAPSYSEEALAILTNKKKNLRILELPFDAQA
ASEVEAEYTGVVGGLLVQNQDVVAENPSDWQVVTDRQPTEQEATALEFAWKAIKYVKSNG
IIITNDHMTLGLGAGQTNRVGSVKIAIEQAKDHLDGAVLASDAFFPFADNIEEVAAAGVK
AIIQPGGSVRDQDSIDAANKHGLTMIFTGVRHFRH
NT seq
1548 nt
NT seq
+upstream
nt +downstream
nt
atgactaaacgtgctttaatctcagtttctgataagtcaggaattattgactttgcaaaa
gaattgaaaaacttgggttgggatattatctcaactggtgggactaaggttgcccttgat
aatgctggagttgagactattgccatcgacgatgtgactggattcccagaaatgatggac
ggtcgtgttaagaccctccatccaaacattcacggtgggcttttggcccgtcgcgatgtt
gacagccaccttcaggctgctaaggataacaatatcgagctgattgacctcgtggttatc
aacctctatcccttcaaggagactatccttcgtccagacgtgacctatgatttggcggtg
gaaaatatcgatatcggcggtccatcaatgcttcgctcagccgcaaaaaaccatgctagc
gtgaccgttgtggttgacccagcggactatgcgactgttttgggagaattagctgacgct
ggtcagacgacatttgaaacgcgtcaacgcttggcagctaaggtctttcgtcacacagca
gcctacgacgctttgattgctgagtacttcacagctcaagtgggagaggctaagcctgaa
aaattaaccatcacttacgaccttaaacaggctatgcgttatggagaaaatccacaacaa
gacgctgatttctatcaaaaagccttgccaacagactactcaattgcttctgctaaacag
ctcaacggaaaagaattgtccttcaataatatccgtgatgccgatgcagcaatccgtatt
atccgcgatttcaaagaccgtccgacagttattgccctcaaacacatgaacccatgtggt
atcggacaggctgatgacattgagactgcttgggattacgcttatgaagctgacccagtt
tcaatctttggtggaattgtcgtccttaaccgtgaagttgacgcagcgacagccaagaag
atgcaccctatcttcttggaaatcatcatcgcaccatcatactcagaagaagcgctagct
attctcacaaataaaaagaaaaacttgcgcatccttgagttgccgtttgatgcccaagct
gccagcgaagtggaagctgagtacactggcgtagttggtggacttttggtgcaaaaccaa
gacgttgtagctgaaaatccatctgactggcaagtggtgacagaccgccaaccaacagaa
caagaggcgactgcccttgagtttgcctggaaggctatcaagtacgttaagtctaacggg
attattattactaacgatcacatgacgcttggactcggtgcaggtcaaaccaaccgtgtc
ggctcagtcaagattgctatcgagcaggctaaagaccaccttgacggtgccgttctagca
tcagatgccttcttcccatttgcggacaacattgaagaagtcgctgccgcaggggtcaaa
gcaatcatccagccaggcggctcagttcgtgaccaagactctattgacgccgcaaacaaa
catggcttgaccatgatcttcacaggtgtgagacattttaggcattaa
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