Streptococcus pyogenes MGAS10750 (serotype M4): MGAS10750_Spy0904
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Entry
MGAS10750_Spy0904 CDS
T00356
Symbol
acoB
Name
(GenBank) Pyruvate dehydrogenase E1 component beta subunit
KO
K00162
pyruvate dehydrogenase E1 component subunit beta [EC:
1.2.4.1
]
Organism
spi
Streptococcus pyogenes MGAS10750 (serotype M4)
Pathway
spi00010
Glycolysis / Gluconeogenesis
spi00020
Citrate cycle (TCA cycle)
spi00620
Pyruvate metabolism
spi00785
Lipoic acid metabolism
spi01100
Metabolic pathways
spi01110
Biosynthesis of secondary metabolites
spi01120
Microbial metabolism in diverse environments
spi01200
Carbon metabolism
spi01210
2-Oxocarboxylic acid metabolism
Module
spi_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
spi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
MGAS10750_Spy0904 (acoB)
00020 Citrate cycle (TCA cycle)
MGAS10750_Spy0904 (acoB)
00620 Pyruvate metabolism
MGAS10750_Spy0904 (acoB)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MGAS10750_Spy0904 (acoB)
Enzymes [BR:
spi01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
MGAS10750_Spy0904 (acoB)
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Gene cluster
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Motif
Pfam:
Transket_pyr
Transketolase_C
PFOR_II
Transketolase_C_1
Motif
Other DBs
NCBI-ProteinID:
ABF37854
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Position
856557..857558
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AA seq
333 aa
AA seq
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MMSETKLMALREAVNLAMTEEMRKDENIFLMGEDVGVYGGDFGTSVGMIEEFGPKRVKDT
PISEAAISGAAIGAAITGLRPIVDVTFMDFLTIMMDAIVNNGAKNNYMFGGGLITPVTFR
VASGSGIGSAAQHSQSLEAWLTHIPGIKVVAPGNANDAKGLLKSAIRDNNIVLFMEPKAL
YGKKEEVNQDPDFYIPLGKGDIKREGTDLTIVSYGRMLERVLQAAEEVAADGINVEVVDP
RTLIPLDKELIIESVKKTGKLMLVNDAYKTGGFIGEIATMITESEAFDYLDHPIVRLASE
DVPVPYARVLEQAILPDVEKIKAAIVKMANKGN
NT seq
1002 nt
NT seq
+upstream
nt +downstream
nt
atgatgtcagaaacaaaattaatggctttgcgtgaagcagtcaaccttgctatgactgag
gaaatgcgcaaggacgaaaacattttccttatgggagaagacgtaggggtttacggagga
gacttcgggacttctgttggaatgattgaagaatttggtcctaaacgtgttaaagatacc
ccaatttcagaagctgctatctctggtgcagctattggtgcagcgattacaggactacgt
ccaattgtcgacgttaccttcatggatttccttactatcatgatggacgctatcgtgaat
aatggtgctaaaaataattacatgttcggtggaggccttattacccctgtaaccttccgt
gtggcatcaggttctggtattggttccgctgcgcaacactcacaatctcttgaagcatgg
ttgactcacattccaggaatcaaagttgttgctcctggtaatgccaacgatgctaaaggc
ttattaaaatcagctatccgtgataataacattgttcttttcatggaaccaaaagcgctt
tatggtaaaaaagaagaagttaaccaagatcctgacttctatatcccacttggcaaaggt
gacatcaaacgtgaaggaactgatttgacaattgtgtcatacggtcgtatgttggagcgt
gttcttcaagcggctgaagaagttgcagcggatggtattaacgttgaagttgttgaccca
cgtaccctcatcccacttgataaagagttgattattgaatctgttaagaaaacaggtaaa
ttgatgcttgtcaatgatgcttacaaaacaggtggattcattggggaaattgcaaccatg
attaccgaaagtgaagcctttgattaccttgatcatccaatcgttcgtcttgcaagtgaa
gatgttccagtaccttatgcacgtgtacttgaacaagcgatcttaccagacgttgagaaa
atcaaagctgctattgtgaaaatggcaaacaaaggcaactag
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