Streptococcus pyogenes MGAS10750 (serotype M4): MGAS10750_Spy1866
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Entry
MGAS10750_Spy1866 CDS
T00356
Symbol
fhs2
Name
(GenBank) Formate--tetrahydrofolate ligase
KO
K01938
formate--tetrahydrofolate ligase [EC:
6.3.4.3
]
Organism
spi
Streptococcus pyogenes MGAS10750 (serotype M4)
Pathway
spi00670
One carbon pool by folate
spi00720
Other carbon fixation pathways
spi01100
Metabolic pathways
spi01120
Microbial metabolism in diverse environments
spi01200
Carbon metabolism
spi01240
Biosynthesis of cofactors
Module
spi_M00140
C1-unit interconversion, prokaryotes
Brite
KEGG Orthology (KO) [BR:
spi00001
]
09100 Metabolism
09102 Energy metabolism
00720 Other carbon fixation pathways
MGAS10750_Spy1866 (fhs2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
MGAS10750_Spy1866 (fhs2)
Enzymes [BR:
spi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.3 formate---tetrahydrofolate ligase
MGAS10750_Spy1866 (fhs2)
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Gene cluster
GFIT
Motif
Pfam:
FTHFS
CbiA
Motif
Other DBs
NCBI-ProteinID:
ABF38816
UniProt:
Q1J4C0
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All DBs
Position
1825885..1827558
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AA seq
557 aa
AA seq
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MVLSDIEIANSVSMEPISKVADQLGIDKEALCLYGKYKAKINARQLVALKDKPDGKLILV
TAISPTPAGEGKTTTSVGLVDALSAIGKKAVIALREPSLGPVFGVKGGAAGGGHAQVVPM
EDINLHFTGDFHAIGVANNLLAALIDNHIHHGNSLGIDSRRITWKRVVDMNDRQLRHIVD
GLQGKVNGVPREDGYDITVASEIMAILCLSENISDLKARLEKIIIGYNYQGEPVTAKDLK
AGGALADLLKDAIHPNLVQTLEHTPALIHGGPFANIAHGCNSVLATKLALKYGDYAVTEA
GFGADLGAEKFIDIKCRMSGLRPAAVVLVATIRALKMHGGVQKTDLATENVQAVVDGLPN
LDKHLANIQDVYGLPVVVAINKFPLDTDAELQAVYDACNKRGVDVVISDVWANGGAGGRE
LAEKVVTLAEQDNQFRFVYEEDDSIETKLTKIVTKVYGGKGITLSPAAKRELADLERLGF
GNYPICMAKTQYSFSDDAKTLGAPTDFTVTISNLKVSAGAGFIVALTGAIMTMPGLPKVP
ASETIDIDEEGNITGLF
NT seq
1674 nt
NT seq
+upstream
nt +downstream
nt
atggttttatcagatattgaaatagccaactctgtctctatggaacctatcagtaaggtt
gccgatcaattagggatcgacaaggaagcgctctgtctctatggtaagtacaaggcaaaa
attaatgcccgtcaactggtcgccttaaaagacaaacctgatggcaaactcattcttgtc
actgctatctcaccaacaccagctggtgaaggcaaaaccaccacttccgttggattggta
gatgctctttctgccattggaaaaaaagcagttattgcccttcgtgaaccttctcttggt
cctgtttttggggttaagggaggagctgctggcggtggccacgcgcaagttgtcccaatg
gaagacatcaaccttcactttacaggggactttcatgccatcggtgtcgccaacaactta
ttagctgccttgattgataaccacattcaccatggcaatagcctaggcattgattccaga
cgtattacttggaaacgtgtggtggatatgaatgaccgccagcttcgtcatattgttgac
ggcttgcaaggcaaggtcaacggggtccctcgtgaggatggttacgacattaccgtcgcc
tctgaaatcatggcaatcctgtgcctatccgaaaatatctctgacctcaaagcccgcctt
gaaaaaatcatcatcggttacaactatcaaggcgaacctgtaacagctaaagacttgaaa
gctggtggtgccctagccgatctgctcaaggacgcgattcatcctaatctcgtgcaaacc
ctggaacacacaccagccctcattcacggtggcccatttgctaatatcgcccatggctgt
aatagtgtcctcgccaccaaactagccttgaaatatggtgattatgccgttaccgaagct
ggatttggtgctgaccttggagctgaaaaattcattgacatcaaatgccgcatgtcaggc
cttcgtccagcagccgttgtcctagtagccactattcgtgcccttaaaatgcacggtggc
gttcaaaaaactgacttggctactgaaaatgttcaagccgttgtggatggtttgcctaac
cttgacaaacatttggctaatatccaagacgtctatggccttccagttgtcgttgcaatc
aataaattcccgcttgataccgatgctgaattacaagctgtctatgatgcctgcaacaaa
cgtggcgttgacgttgtgatttctgatgtttgggcaaatggcggagctggtggccgtgaa
ctggctgaaaaagtcgtgacactagccgagcaagacaatcaattccgctttgtttatgag
gaagacgatagcattgaaaccaaactgactaaaatcgttaccaaagtttacggtggtaaa
ggcatcaccttgagcccagcagccaaacgtgaactggctgacttagaacgcctaggcttt
ggcaactacccaatttgcatggccaaaacccaatattccttctcagacgatgccaaaaca
cttggcgcaccaactgactttacagtgactattagcaacctcaaagtgtctgcaggagca
ggatttatcgttgctctgacgggtgctatcatgaccatgcctggccttccaaaagtacct
gccagcgaaaccattgatattgacgaggagggcaacatcacaggactattctaa
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