Spirosoma sp. KCTC 42546: EXU85_28865
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Entry
EXU85_28865 CDS
T06164
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
spik
Spirosoma sp. KCTC 42546
Pathway
spik00260
Glycine, serine and threonine metabolism
spik00261
Monobactam biosynthesis
spik00270
Cysteine and methionine metabolism
spik00300
Lysine biosynthesis
spik01100
Metabolic pathways
spik01110
Biosynthesis of secondary metabolites
spik01120
Microbial metabolism in diverse environments
spik01230
Biosynthesis of amino acids
Module
spik_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
spik_M00527
Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine
Brite
KEGG Orthology (KO) [BR:
spik00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
EXU85_28865 (thrA)
00270 Cysteine and methionine metabolism
EXU85_28865 (thrA)
00300 Lysine biosynthesis
EXU85_28865 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
EXU85_28865 (thrA)
Enzymes [BR:
spik01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
EXU85_28865 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
EXU85_28865 (thrA)
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GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
ACT_7
ACT
NAD_binding_3
Motif
Other DBs
NCBI-ProteinID:
QDK82404
UniProt:
A0A515A6G4
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All DBs
Position
7060683..7063139
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AA seq
818 aa
AA seq
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MQVLKFGGTSVGSVESIKQVIQIIDNHRQNGDQIAVVFSAMGGVTNQLIEIGRMATSGEP
DYMELVRRIEDRHFNVVKALIPVKEQSKVFAHVRGIINELEDLLRGVSLIRELTLRTHDL
ITSFGERLSTTIITECVKSRGIPAQFCDARQIIKTDAQFGQAEVNYSLTNQLIQEHFAKS
TTTQMVTGFIGSTEKNETTTLGRGGSDYTASILGAALNAEVIDIWTDVDGMMTADPRKVP
NAFNIPTITYAEAMELSHFGAKVIYPPSLQPAFARNIPIRVLNTFNPTHEGTVVSRTAER
RQYTITGISSIDDIALVNVQGSGMIGVAGVSAKLFGVLAAHKISVILISQASSEHSICFA
IDPRGAENVKTILDAEFATEIEHGHIDNIAIERDLSVIATVGEGMKKSSGIAGKLFSVLG
KNGVNIVAVAQGSSEINISVVINKNNLSKALNSLHNIFFQSEARVLNLYLVGIGLIGKTL
LKQIFDQSEYLRTEKLLKVCVVGMTNTKKMLLDPKGIALDDWRERVLTEGVTTSLPAFVD
KIKDYNLPNSVFIDCTSDKDIVQFYESLLDSNISVVTPNKVANSGPYAEYRRLQRTALNR
GVKFLYETNVGAGLPIINTVQGLMTSGDRFLKIEAILSGTLSFIFNTFRPGTSFANVVRE
AKEKGYTEPDPRDDLSGLDVARKILILAREAGFPLEPEDVTITPLLPESCQAAPTVPAFF
EELERNNDYFENLLAEATAKGEKLRFVARFENNKATIGLRSVDSEHPFYQLTGADNIISF
TTERYKDRPLVIKGPGAGAEVTASGVFADVVSIGSYLA
NT seq
2457 nt
NT seq
+upstream
nt +downstream
nt
atgcaggttcttaaattcggtggcacctcggtcggttccgtagaaagcatcaaacaagtc
atccaaatcattgataatcatcgccaaaacggtgatcagatagccgttgtattctcggcg
atggggggcgtaacaaaccagctcatcgaaattggacgaatggcgacgtcgggagagccg
gattatatggaactggtccgacgaattgaagaccggcatttcaatgtggtgaaagcgttg
attcccgtaaaagaacaaagcaaagtatttgcccacgttcggggcattatcaatgaactg
gaagacctgctacggggtgtatcgctcattcgcgaattgacactgcgcacgcatgacctc
atcaccagttttggcgaacggttatccacaaccatcatcaccgaatgtgtaaaaagtcgg
gggattcccgcgcaattctgcgatgcccgtcagattatcaaaaccgatgcccagtttggc
caggctgaagtaaactattcccttacgaatcaactcattcaggagcattttgcgaagtcc
acaactacgcaaatggtaacgggttttatcggatcgactgaaaagaacgaaacgacaacc
cttgggcgaggtggctcagattatacggccagcatccttggcgcagcactaaatgccgaa
gtcatcgacatctggaccgacgttgacggcatgatgacggccgatccacgcaaggtgccg
aatgccttcaatatcccaacgatcacctacgccgaagctatggagcttagtcacttcggt
gcgaaagtgatttatccaccgagtctacaaccggcgttcgcccgtaacattccgattcgc
gtactcaatacattcaatcctacacacgaaggcacggttgtgagccgcaccgccgaacgt
cggcaatacaccattacgggtatttcaagcatcgacgacatcgctcttgtgaacgtacag
ggatcgggcatgattggcgtagcgggtgtatcggcaaagttgtttggcgtattggccgcg
cataagatcagcgtcattctgatctcgcaggcatcatcggagcattccatttgtttcgct
atcgacccacgtggggctgaaaatgtaaagaccattttagatgccgaattcgcgactgaa
attgaacacggccatatcgataacatcgccatcgagcgcgatttgtcggtgattgcgaca
gttggcgaaggcatgaaaaaaagctcaggtattgccggaaaattattttcggtactgggt
aaaaacggggttaatatcgtagctgtagcgcagggatcatcggagatcaacatctcggta
gttatcaacaaaaataacctttccaaggcccttaactcgctgcataacatcttcttccaa
tccgaagcacgggtacttaacctgtatttagttggcatcggattgattggcaaaacactc
ctgaagcagattttcgaccagtctgaatacctgcgcacggaaaagctgctaaaagtatgc
gttgtgggcatgacgaacaccaaaaagatgctccttgacccaaaaggcatcgccctggat
gactggcgtgaacgagtactcacggaaggcgttaccacctccttacccgcgtttgtcgac
aaaataaaagattacaacctacctaactcggttttcattgactgcacatcagacaaggat
atcgtgcagttttacgagtcgcttttggatagcaacatctccgttgttacgcccaataaa
gtagccaattccggcccttatgccgagtatcggcgactacaacggactgcattgaaccgg
ggggttaagtttctctacgaaaccaatgttggcgcgggtctgcctattatcaacaccgtt
cagggattgatgacgtccggcgaccgtttcctgaaaatagaagcgattttatcgggtact
ttatccttcattttcaacacattccgccctggtacgtcctttgctaatgtagtgcgtgaa
gccaaagaaaaaggatacaccgagcctgacccacgcgatgatttgagcggcctggacgta
gctcgaaaaattctaattctggcgcgtgaagccggttttccactcgaaccagaggatgtc
accataacgcctttattgcctgagtcctgccaggctgcccctaccgttccagcattcttt
gaggaattggagcgcaataatgattacttcgagaatctgctggccgaagcaacagccaaa
ggggagaaactacgatttgtcgcccgtttcgagaataacaaagcgaccattggccttcgc
tcggtcgattctgaacatccattctaccagctaaccggtgccgacaacatcatttcattt
acgacggaacgctacaaagatcgcccgctcgtcatcaaaggccccggtgcaggagccgaa
gtaacggcctcgggcgtatttgccgatgtggtgagtatcgggagttatttggcgtaa
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