Sardina pilchardus (sardine): 134059974
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Entry
134059974 CDS
T10667
Symbol
zgc:158659
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X1
KO
K00922
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:
2.7.1.153
]
Organism
spil Sardina pilchardus (sardine)
Pathway
spil00562
Inositol phosphate metabolism
spil01100
Metabolic pathways
spil04012
ErbB signaling pathway
spil04068
FoxO signaling pathway
spil04070
Phosphatidylinositol signaling system
spil04081
Hormone signaling
spil04140
Autophagy - animal
spil04150
mTOR signaling pathway
spil04210
Apoptosis
spil04218
Cellular senescence
spil04370
VEGF signaling pathway
spil04510
Focal adhesion
spil04620
Toll-like receptor signaling pathway
spil04625
C-type lectin receptor signaling pathway
spil04810
Regulation of actin cytoskeleton
spil04910
Insulin signaling pathway
spil04914
Progesterone-mediated oocyte maturation
spil05100
Bacterial invasion of epithelial cells
spil05132
Salmonella infection
spil05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
spil00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
134059974 (zgc:158659)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
134059974 (zgc:158659)
04370 VEGF signaling pathway
134059974 (zgc:158659)
04068 FoxO signaling pathway
134059974 (zgc:158659)
04070 Phosphatidylinositol signaling system
134059974 (zgc:158659)
04150 mTOR signaling pathway
134059974 (zgc:158659)
09133 Signaling molecules and interaction
04081 Hormone signaling
134059974 (zgc:158659)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
134059974 (zgc:158659)
09143 Cell growth and death
04210 Apoptosis
134059974 (zgc:158659)
04218 Cellular senescence
134059974 (zgc:158659)
09144 Cellular community - eukaryotes
04510 Focal adhesion
134059974 (zgc:158659)
09142 Cell motility
04810 Regulation of actin cytoskeleton
134059974 (zgc:158659)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
134059974 (zgc:158659)
04625 C-type lectin receptor signaling pathway
134059974 (zgc:158659)
09152 Endocrine system
04910 Insulin signaling pathway
134059974 (zgc:158659)
04914 Progesterone-mediated oocyte maturation
134059974 (zgc:158659)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
134059974 (zgc:158659)
09171 Infectious disease: bacterial
05132 Salmonella infection
134059974 (zgc:158659)
05100 Bacterial invasion of epithelial cells
134059974 (zgc:158659)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
spil04131
]
134059974 (zgc:158659)
Enzymes [BR:
spil01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase
134059974 (zgc:158659)
Membrane trafficking [BR:
spil04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
134059974 (zgc:158659)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI3Ka
PI3_PI4_kinase
PI3K_C2
PI3K_p85B
PI3K_rbd
ABC1
Ig_NOMO
DUF2321
Motif
Other DBs
NCBI-GeneID:
134059974
NCBI-ProteinID:
XP_062372520
LinkDB
All DBs
Position
16:611327..637451
Genome browser
AA seq
1072 aa
AA seq
DB search
MAPRPSSGELWGLHLMPPRILVDCCLPNGMLVSLECLREAPLLTIKQQLFAEARKYPLYH
LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFQPLLKVIEPIGNREEKILNREIGFA
IGMPICEFELVKDSEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSPDLPPH
IYSKLDKGRLIVTIWVIVSPSNAKQKYTLKISHDSLPEQLIAEAIRKKTRSMHLSAQQLR
MCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVAPSYSRRTPQPSPCPGGTDPSPPRSLWAFNTLLRLRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLTDLPRATRLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYKDTLVSGKVALSLWPVPHGMEDLLNPIGVAGSNPNKETPCVELEFS
WFSQTVIFPDEQQIEEHANWVVSRELGYNYCMGLSSRLACDSTVSQADGEQLRSLCSRDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLQAVKWNSRDEVSQMYCLLKDWPLMQPESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKVKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKR
PLWLNWENPDIMSELLFTNNEVIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYG
CLSIGDCVGLIEVVKNSYTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDKAIDLF
TRSCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLT
QDFLIVISKGVQECTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFD
DIAYLRKTLALEKSQQEALEYFTKQMNDAHHGGWTTKMDWIFHTIRHMPNEH
NT seq
3219 nt
NT seq
+upstream
nt +downstream
nt
atggcccctcggccgtcctcgggggagctatggggcctccacctcatgcccccacgcatc
ctggtggactgttgcctgcccaacggtatgctggtcagcctcgagtgcctgcgtgaggcg
ccactgctcaccatcaagcagcagctgttcgccgaggcccgcaagtacccgctctaccac
ctgctgcaggaggagtcctgctacatctttgtgggtgtgacccaggaggctgagagggag
gagttctatgatgagacgcgtcgtctgtgtgacctgcgcctctttcagcctcttctcaaa
gtcatcgagccaataggcaatcgagaggaaaagatcctcaatcgcgagattgggtttgcc
ataggcatgcccatctgtgagtttgagctggtgaaggactcggaggtgcaggacttccgg
cggagcatactgagcgtgtgcagagaggccatggaggagagggaggggggtggcgcccac
tctcaggcactctacgtctaccctcccaatgtggagtcctccccggacctgcccccccac
atctactccaagctggacaaaggtcgcctgatcgtgaccatctgggtgatcgtgtctccg
tccaacgccaagcagaagtacacgctgaagatcagccacgacagcctgcccgagcagctc
atcgccgaggccatccgcaagaagacgcgcagcatgcacctgtcggcgcagcagctgcgc
atgtgcgtgcaggagtaccagggccagtacatcctcaaggtgtgcggctgcgacgagtac
ctgctggagaagtacccgctcagtcagtacaagtatatccgtagttgcatcatcgtgggc
cggctgccccacttgatgctggtgtccaaggacagcctgtacagccagctcccggccagc
ggcttcgtggcgccctcctacagccgccgcacgccccagcccagcccctgccccggcggc
accgacccctcgccaccacgctccctctgggccttcaacaccctgctgcgcctgcgcctg
ctctgtgccacctacgtcaacgtcaacatcagggacatcgacaagatttatgtcagaaca
ggcatctatcatgggggagagccactgtgtgacaacgtgaacacacagagagtgccctgc
tccaaccccaggtggaatgaatggctgacgtacgacatctacctgaccgatctcccgcgt
gccactcgtctctgtctctccatctgctcagtgaagggacgcaagggagccaaagaggag
cactgtccactggcctggggcaatgtgaatctgtttgactacaaggacacgttggtgagt
gggaaggtggccctgagcctgtggcctgtgccgcatggcatggaggacctgctcaacccc
atcggcgtcgctggatccaaccccaacaaggagactccgtgtgtggagctggagttctcc
tggttcagccagacggtcattttcccagacgagcagcagattgaggagcacgccaactgg
gtcgtctccagagagctgggctacaactactgcatgggcctgagcagtcggctggcgtgt
gacagcacggtgtcgcaggcggacggcgagcagttgcgcagcctgtgcagccgagacccg
ctctatgagctctcagagcaggagaaggacttcctgtggaggcaccggcactactgtgtg
aacatcccagagagccttcccaagctgctgcaggccgtcaagtggaactcccgtgacgag
gtgtctcagatgtactgtctgctgaaggactggcctctgatgcagccggagtcggctctg
gagctgctggactgtaacttccccgaccccatggtgcgcgagtttgccctgcgctgtctg
gtgcagggcctcaccgacgacaagctaagccagtacctgctgcagctcgtgcaggtactg
aagtacgagatgtaccttgataatcctctagcccgcttcctcattaagaaagccctgacc
aatcagagaataggacacttcttcttctggcatctcaagtcggagatgcacaataagaca
gtgtctcggcgcttcggcctgctgttggaggccttctgtcgggcgtgcgggatgtacctg
aagcacctgaatcgacaggtggaggccatggacaagctggtcaacttgacggacacactc
aagcaggagaagaaagacgagacccagaaggtaaagacccagatgaagttcctggtggag
cacatgtcccggccggactacatggaggccctgcagggtttcgtctcccccctgaacccc
gtccaccaactgggcaacctcaggttagaggaatgcagaatcatgtcctcagcaaagcgt
cccctgtggctgaactgggagaatcctgacatcatgagtgaactgctgtttaccaacaat
gaggtcatcttcaaaaacggggatgatctgcggcaggatatgctcactctccagatcatt
aaaattatggagaacatctggcaaaaccagggcttggatctgagaatgctgccgtatggc
tgcctgtccataggtgactgcgtggggctgatcgaggtggtgaagaactcctacaccatc
atgcagatccagtgcaagggaggcctcaagggggcgctgcagttcaacagcaatactctg
caccactggatcaaagacaagaaccgcggcgaggcgtatgataaagcgatagatctgttc
actcgctcatgtgctggctactgtgtggccaccttcatcctgggcattggggaccggcac
aacagcaacatcatggtgaaagagaacggacagctgtttcacatagactttggtcatttc
ctggaccataagaagaagaaatttggctacaagcgtgaacgagtgccatttgtgctcact
caggacttcctcatagtcatcagcaagggcgtacaggagtgcaccaagactaaggagttt
gagaggttccaggagatgtgctataaggcctacctggccatccgtcagcatgccagcctc
ttcatcaacctgttctcgctgctgctgggctgtggcatgcctgagctgcagagcttcgat
gacatcgcctacctgcgcaagacgctggcgctggagaagagccagcaggaggcgctagag
tacttcaccaagcagatgaacgacgcccaccacggcggctggaccaccaagatggactgg
atcttccacaccatccgccacatgcccaacgagcattaa
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