Sardina pilchardus (sardine): 134067936 Help Entry 134067936         CDS       T10667                                  Name (RefSeq) ryanodine receptor 3-like   KO K04963   ryanodine receptor 3 Organism spil  Sardina pilchardus (sardine) Pathway spil04020   Calcium signaling pathway spil04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:spil00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     134067936    04020 Calcium signaling pathway     134067936  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:spil04040]     134067936 Ion channels [BR:spil04040]  Voltage-gated cation channels   Ryanodine receptor    134067936 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 SPRY MIR Ins145_P3_rec RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_6 Motif Other DBs NCBI-GeneID:  134067936 NCBI-ProteinID:  XP_062379408 LinkDB All DBs Position 20:905071..1077203 Genome browser AA seq 4894 aa AA seqDB search MTQCLPQTQAVASKTDDEVVLQCVACIQKENRKFCLTAEGLGNRLCYLEPTSEAKFVPPD LCICNFVLEQSLSVRALQEMLAKTGLNNEVSITHAAAQGGGHRTLLYGHAILLRHSFSGM YLTCLKTSRSLTDKLSFDVGLQEDSTGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSS ERYLHLSISNGNIQVDASFMQTLWNVHPTCSGSNVEEGYLLGGHVMRLFHGHDEVLTIPA SDQSEEQQRIVNYETGKAGAKARSLWRLEPLKISWSGSHMRWGQPFRLRHLTTGHYLALT EDQGLVIEDRERSDTASTAFCFRVSKEKLESSPKRDIEGMGVGEIKYGDSICFVMHMATG LWLSYQAPDAKSARLGPLKRRACLHSEGHMDDGLTLQRCQHEESCAARIIRNTTRLFSRF IRDLESLGGKNRVAVTLPIEEVLQTLKDLITYFQLPDAELEHEEKQIKLRSLKNRQNLFK QEGMLTLVSNCIDRLSLYNSAAHFGECAGEEAGEAWKDILNLLYELLAALIRGNRNNCTQ FSHNLDWLVSKLERLESSSGILEVLHCILIESPEALNIIQRGHIKSIISLLYKHGRNHKI LDVLCSLCVCNGVAVRANQNLICDYLLPRRDLLLQTRLVNDVHSMRPNIFLGVREGSAQY KKWYFELMIDQVDHFVTSEPSHLRVGWANTKGYAPYPGGGEGWGGNGVGDDLYSYGFDGL HLWSGRIPRAVASVNQHVLTSDDVVSCCMDLGAPSISFRINGQPVQGMFENFNVDGLFFP VVSFSAGVKVRFLLGGRHGDFKFLPPSGYAPCYEALLPREKMRVEPVKEYKRDAEGVRDL LGTAQFLSQASFIPTPVDTSQIVMPPHLEKVRDKLAENIHELWAMNKIELGWSYGKIRDD NKRQHPCLVDFSKLPETEKNYNLQMSTETLKTLLALGCHVVQVNANAEDDLKKVKLPKNY MMSNGYKPTPLELSDVKLTPAQELLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKNKRNP RLVPYALLDERTKKSNRDSLREAIRTLIGYGYNIEPPDQEGGHAVERLSIDKIRFFRVER TYAVKTGKWYFEFEAVTGGDMRVGWARPACRPDVELGTDDLAFVFDGYKGHRLHMGSRLF GRCWHAGDVVGCMINMEDKSMIFTLNGEILITNKGSELCFADFETEDGFIPVCSLGLSQV GRMNLGKDASTFKYYTMCGLQEGFEPFAVNMNREVTMWFSKRLPTFVNVPKDHNHIAVTR IDGTIDSPPCLKVTHRTFGTQNSNADMVFCRLSMPVEFHSTFKITASMDINGVHEDEALK LKHRHTVKSMKHIEDGRRTDYSSITMYYHSVRVFAGQDPSCVWVGWVTPDYHYHSNNFNL SKNRSVTVTLGDERGRVHESVKRSNCYMVWCGDITSSSHSSSRSNVDLELGCFIDLSTGL VAFTVNGKELTTSYQVEPNTKLFPAVFVLPTSPNLFQFELAKIKNTMPLSSAVFKSEHRN PVPQCPPRLDVQTINAVLWSRMPNCFLKVETARVSERHGWAVQCVEPLQMLAVHIPEENR CVDIMELSEQEDLRKFHYHTLKLYCALCALGNTRVAHALCSHLDQAQLLYTIDNQYLSGQ LREGFYDALISIHLETAKEARLMMNNEFIIPVTAETRSIRLFSDASKKHQPPGVGLSTSL KPRLHFGPPCFISSTKREQHLYSPQIPLDVLKEKAISMLTEAVQGGGDHIRDPVGGSVEY QFVPILKLIGTLLTMGVLASHDVHKILLLIEPNVFGEQREETGGGGGGVGGGDGVGKEGM SSAEEKAVEAGEAEAKDAKQPRKGLLEKRLPESVKRQMCELLHYFCDCELKHRIEAIVSF SDIFVSKLQFNQKFRYNELMLALNMSAAVTAKKTKEFRSPPQEQINMLLNFSTGEDCPCP EEIQEELYKFHNELRLHCGIPMEEEEEEPDLTIRGRLMALVYKIKGHPQKTEQEPKEKEL AAPTNLKELISQTMVCWAQESHIQDPELVRVMFSLLRRQYDSIGELLRAMRKSYTISASS VLDTIHLLASLGQIRSLLSVRMGKEEEQLMIDGLGDIMNNKVFYQHPNLMRVLGMHETVM EVMVNVLGGGKSQEIAFPKMVASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASP SMRGSTPLDVAASSVMDNNGLALALEEPDLDKVVTYLAGCGLQSCPILLAKGYPDIGWNP IEGERYLSFLRFAVFVNGESVEENSSVVVKLLIRRPECFGPALRGEGGNGLLAAMKEAIK ISESPALDLPSAAQGISSDASTEDDEEEEVVHMGNAIMSFYSALIDLLGRCAPEMHLINK GKGEALRIRAILRSLVPTEDLVGIISIPLKMPIINKDGTVTEPDMSASFCPDHKAPMVLF LDRVYGIEDQAFLLHLLEVGFLPDLRASATLDTDTLRTTETALAMNRYIGSAMLPLLTRC APHFAGTEHHAALIDSTLHTIYRLSKGRSLTKAQRDAIEECLLAICKYLRPSMLQQLLRR LVFDVPLLTEYCKMPLKLLTNHYEQNWKYYCLPSGSGNYGMASEEELLLTKKIFWGIFDS LSQKKYDQDLFKMAMPCLSAIAGALPPDYVDSSLSNTSLEKTSSVDQQGNFDPKPISTAN ISIPEKLEYVANKYAEHCHDKWSAEKVLLGWKYGDGIDEKAKIHHLLRSYKSLTEKEKEI YRWPVRESLKSMLAMGWNIDRTKEGETMSQQSEKLRKASQGNGFNPSPLDMSTVLLSREL QGMVEVVAENYHNIWAKKKKSDLGSRGGGTHPLLVPYDTLTAKEKAKDREKAQDLFRFLQ INGYSITRGLKDMEQDSSSMEKRFAYKFVKKLLKYVDSAQEFIAHLEAMAMSGKMDRSPH EQEIKFFAKVLLPLIDQYFKNHCFYFLSSPSKNLSSSGYASNKEKEMVTSLFCKLAALVR HRISLFGSDAATMVSCLHILAHTLDTRTVMKSGSELVKAGMWTFFENAAEDLEKTLENLK LGKFTHSRSQMKGVSQNINYTTVALLPILTALFEHITEHHFGVDLLLDDVQVSCYRILTS LYSLGTGKNIYVERQLPALGECLATLAGAMPVAFLEPQLNTHNPCSVFNTKTPRERAILG MPDTVEDMCSEIPRLGGLMKDINDLSESGARYTEMPHVIEVVLPMLCNYLSYWWERGPEN QAATLKSGAGPICCATVTSEHLSVILGNILKILNSNLGIDEASWMKRIAVYAQPIISKAR ADLLKTHFLPTLDKLKKKTVKVVTEEELLKADSKGDTQEAELLILDEFAVLCRDLYAFYP MLIRYVDNNRSRWLKEPDADSNELFRMVAEIFILWCKSHNFKREEQNFVVQNEINNLSFL TGDSKTKMSKSGGQDQERKHKKRRGEFYSIQTSLIVAALKKMLPIGLNMCTPGDQELISL AKTRYSLKDTDDEVKDHIRHNLHLQEKSEDPAVRWQLNLYKDVVVRNEGPPDPERTVARV QGLSAAVFHLEQVEQPLRSKKCVWQKLLSKQRKRAVVACFRMAPLYNLPRHRSINLFLLG YQRIWIETETYSFEEKLVQDLAKTQVKLEEEEEVEAEKQPDPLHQLILHFSHNALTERSS LDEDPLYMAYADMMAKSCAEDGEEEEGEGKSFEEKEMEKQKTLYQQARLHDRGAAEMVLQ MISASKGRLDPMVTYTLKLGISILNGGNIIVQQKMLDYLKEKRDVGFFKSLSGLMQSCSV LDLNAFERQNKAEGLGMVTEEGSSSKVLQNDEFTKDLFRFLQLLCEGHNNDFQNFLRTQT GNTTTVNIIISTVDYLLRLQESISDFYWYYSGKDVMDEAGQRNFSKALAVAKQIFNSLTE YIQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMKLSQDSSQIELLKELMDLQKDMIVMM LSLLEGNVVNGTIGKQMVDTLVESSSNVEMILKFFDMFLKLKDLTTSDNFKEYDPDSKGA ISKKEFQKSMENQKQYSQSEIEFLLSCVKADENDMFNYEEFVERFHEPAKDIGFNVAVLL TNLSEHMPHDGRLAAFLDLGESLLSYFEPYLGRIEILGSGKRIERVYFEISESSRTQWEK PQVKESKRQFIFDVVNEGGESEKMELFVNFCEDTIFEMQLASQISEPDALERPEEDEEDD VASVAEEADEDDEDNALESSSAFAVACVSMKKSFSGFWKLLTFKSMRRQYKRFRKMSVRE MVRGFFSFFWVIFTGLFRFLYSLVWGFFHILWSSMFGGGLVEGAKNMKVTDILGNMPDPT QFGIHGDVLEAEKMEACEGALSVTEMEQNAAADQAEADLMAELLNIQPKKEGGKHVEPGL GDVSEVVGVDAPSIAAAVRQKKAQKEAAHKKAEAEAEREQREGEKTDLEDGEKKDLDKNR DETPPNTPAEEERRLPKKRPRQKEEPPEAFMASFFAGLEIYQTKMLNYLARNFYNLRFLA LFVAFAINFILLFYKVIWHSNSVTLYLYEEDPWNGGQVEEEEGAMEYFVLQESTGYMAPT LRFLAVLHTLISFLCVVGYYYLKVPLVVFKREKEIARKLEFDGLYITEQPSDDDIKGQWD RLVINTPSFPNNYWDKFVKRKVINKYGDLYGAERIAELLGLDKSALDFNPTEEAVVKEAS LVSWLSSIDTKYHIWKLGVVFTDNSFLYLVWYTTMSILGHYNNFFFAAHLLDIAMGFKTL RTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCY LFHMYVGVRAGGGIGDEIEDPAGDPYELYRILFDITFFFFVIVILLAIIQGLIIDAFGEL RDQQEQVKEDMETKCFICGIGNDYFDTTPHGFETHTLQEHNLANYLFFLMYIINKDETEH TGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLG NT seq 14685 nt NT seq  +upstreamnt  +downstreamnt atgacgcagtgccttcctcaaacccaggcggttgcttcaaagacggatgatgaggtggtg ctccaatgtgtcgcctgcatccagaaagagaaccgcaagttctgcctcaccgccgagggg ctggggaatcgcctctgctacctggagcccacctcagaggctaagtttgttcctccagat ctatgcatctgtaactttgtgctggagcagtctctatcagtgcgagctctgcaggaaatg ctggccaaaacaggactgaacaatgaagtgagtatcacccatgcagcagctcaagggggt ggtcaccgaaccctgctgtacggtcatgccatcctgctcaggcactccttcagtggaatg tacctgacctgtttaaagacatcacggtctctgactgacaagctgtctttcgatgtggga ctgcaagaagactcgacaggtgaggcgtgttggtggaccatccaccctgcgtccaagcag cgctctgaaggagagaaggtgcgcatcggggatgacctcattctcgtcagcgtgtcttcg gagcgctacctgcacctctctatctccaatggaaacatccaagttgatgcgtccttcatg cagaccctgtggaacgtccaccccacctgctcaggaagcaacgtggaggaaggctatctg ctgggtggccatgtgatgcgtctgttccatgggcatgacgaggtcctcaccatcccagcc tcagatcagagtgaagaacagcagaggatagtgaactatgagacaggaaaagcaggcgcc aaggccaggtcgctatggagattggagccactgaagatcagttggagtgggagccacatg cgctgggggcagccattccgcctgcgccacctgaccaccgggcactacctggcactgacg gaggaccaggggctggtgatcgaggaccgggagagatctgacacggcatccactgccttc tgcttcagagtctccaaggaaaagctggagtccagtcccaagagagacattgagggcatg ggagtgggcgagatcaagtatggagactccatctgcttcgtcatgcacatggccacaggg ctgtggctgtcctaccaggcgcctgatgcaaaatctgcccgtctaggacccctcaagaga cgggcgtgcctccactccgaggggcacatggatgatggcctgaccctacagcgctgtcag catgaggagtcctgtgcggcccgcatcatccgcaacaccacccgactcttcagccgcttc attagggacttggagagtctggggggaaagaaccgtgtggccgtgactctccccatcgag gaggttctccagacactcaaagacctcatcacctacttccagctcccagacgctgagcta gaacacgaagagaagcagatcaaactgcgctccctcaagaaccgccagaacctcttcaag caggaggggatgctaactttggtgtctaactgcattgaccggctgagtctgtacaacagt gcggcccactttggggagtgtgcaggggaggaggccggggaggcctggaaggatatcctc aacctgctgtacgaactgctggctgcactgatccggggaaataggaataactgcacccaa ttctcacacaatctggactggctggtcagcaaattggagaggctggagtcatcatcaggc attctggaggtcctgcactgcatcctaatcgagagccctgaggcgctcaacatcatccag aggggacacattaagtccatcatctctctgctctacaaacacggacgcaaccacaagatc ctggatgtgttgtgttcgttgtgcgtctgcaatggcgtggcagtgagagccaatcagaat ctcatctgcgattacttgctccccagaagagatctgttactccagacgcgattggtcaat gatgtccacagcatgaggcctaacatcttccttggcgtgagagagggctctgcgcagtac aagaagtggtactttgagctgatgatcgaccaggtggaccactttgtcaccagtgagcca tctcacctgagagtgggctgggccaacaccaaaggctacgccccttaccctgggggaggg gagggctgggggggcaacggtgttggagatgacctctactcctatggcttcgacgggctg catctgtggtcaggtcgtatcccgcgggccgtggcctcggtgaaccagcacgtgctgacc tcagatgacgtggtgagctgctgcatggacctgggcgctcccagcatctccttccgcatc aacggccagcctgtgcagggcatgttcgagaacttcaacgtggacggactcttcttccct gtagtgagcttctccgccggagtcaaggtgcgctttctgctgggcggtcgccatggtgac tttaagttcctgcctccgtcgggctacgcgccgtgctacgaggcgctgctgccgcgggag aagatgcgcgtggagccggtcaaggagtacaagagggacgccgagggcgtccgagacctg ctgggcaccgcacagttcctctcccaggcctccttcatccccacgcccgtggacaccagc cagatcgtcatgcctccccacctagagaaggtgcgagacaaactcgccgagaacatccac gagctctgggccatgaacaagatcgagctgggctggtcttacggcaagatcagagatgac aataagagacaacacccctgcctggtggacttctccaagctgcctgaaaccgaaaagaat tataacctccagatgtcaacagaaaccttgaagacactgctggctctaggatgtcatgtg gtacaagtcaatgctaatgcagaggacgacctgaagaaagtcaaactcccaaagaactac atgatgtcaaatggctataagcccacgcctctggagctgtcagacgtgaagctcacacca gcccaggagctgttggtggataagctggcagagaacgcccacaacgtttgggccaaggac cgcatcaagcagggatggacctatggcatccagcaggacctgaagaataagcgcaacccc cgtctagtgccctacgcgctgcttgatgagcgcacaaagaagtccaatcgagacagctta cgggaagccatccgcacactcattggctatggctacaacatagaaccacctgaccaggaa gggggtcacgcggtggagaggctgagcatcgataagatccgcttcttccgggtggagcgc acgtatgcggtgaagacagggaagtggtactttgagtttgaggcggtaacggggggagac atgcgcgtgggctgggcccggcctgcctgtaggccagatgtggagctggggacggacgac ctggcctttgtgttcgatggctacaagggtcaccggctgcatatgggcagtcgtctcttt ggccggtgttggcacgcaggtgatgtggtgggctgtatgattaacatggaggacaagtcc atgatcttcaccctcaacggagagattctcatcaccaacaagggctccgagctctgcttt gctgacttcgagacggaggatggattcatccctgtgtgcagtctgggtctgtcccaggtg ggccggatgaacctgggcaaagatgccagcacctttaagtactacaccatgtgtgggctg caggagggctttgagccatttgctgtcaacatgaaccgtgaggtcacgatgtggtttagc aagcgcctgcccacctttgtcaacgtgccaaaagaccacaatcacattgcggtgaccagg atcgacggcaccattgacagcccgccgtgtctgaaggttacccacaggacctttgggacg cagaacagcaacgctgacatggtgttctgccgactgagcatgcccgtggagttccactcc accttcaagatcaccgcctccatggacatcaacggagtgcacgaggacgaggcgctcaag cttaaacacagacacacagtgaaatccatgaaacacatagaggacggaaggagaactgac tacagcagcattaccatgtactaccactctgtgagggtgtttgctggacaggacccgtcc tgtgtgtgggtgggttgggtcacccctgactaccattaccatagcaacaacttcaacctc agtaagaatcggagcgtcactgtaaccctgggagatgagcgcgggcgggtccatgagagt gtaaagaggagtaactgctacatggtgtggtgtggggacatcactagctccagccactcg tccagccgcagtaatgtggatctggagctgggctgcttcattgacctctccactggcctt gtggccttcactgtcaatggcaaagagctgaccacttcgtaccaggtggagccgaataca aagctcttccctgctgtgtttgtgctccccaccagtcctaacctattccagtttgaactg gccaagatcaagaacaccatgcccctgtcgtcggcggtgtttaagagtgagcaccgtaac cctgtgccccagtgtccaccccggctggacgtgcagaccatcaacgccgtgctgtggagc cgcatgcccaactgcttcctgaaggtggagacggcgcgggtcagcgagaggcacggctgg gctgtccagtgtgtggagccgctgcagatgctggccgttcacatccctgaggaaaacagg tgtgtggacattatggagctgtcggagcaggaggacctgcgtaagttccactaccacacg ctcaagctgtactgtgccctctgtgccctgggcaacacccgcgtggcacacgccctgtgc agccacctggaccaggcccagctgctctacaccatcgacaaccagtacctgtcggggcag ctgcgcgagggcttctacgacgcgctgatcagcatccacctggagacggccaaggaggcg cgcctgatgatgaacaacgagttcatcatccccgtcaccgcggagacgcgcagcatccgc ctcttctccgacgcctccaagaagcaccagcccccgggcgtgggcctgagcacgtcgctg aagccgcggctgcacttcggcccgccctgcttcatctccagcaccaagcgagagcagcac ctgtacagcccgcagatcccactggacgtgctcaaggagaaggccatctccatgctcaca gaggccgtgcagggtggcggtgatcacatccgggacccggtgggcggcagcgtggagtac cagtttgtgcccatcctcaagctcatcggcacactgctcaccatgggggtgttggccagc cacgacgtccacaagatcctgctgctcattgagcccaacgtgttcggagagcagagggag gagactggaggtggtggtggaggagtaggtggaggagacggagtggggaaggaggggatg agcagtgcggaggagaaagcggtggaggctggggaggcggaggccaaagatgccaagcag cccaggaagggactactggagaagaggctgcctgagtcagtcaaacgacagatgtgtgag cttcttcactacttctgtgactgtgagctgaagcaccgcatcgaggccatcgtctccttc tcggacatctttgtgtctaagctgcagttcaaccagaagttccgctacaacgagctcatg ctggcactcaacatgtccgctgccgtgaccgccaagaagaccaaggagttccgctcacca ccccaggagcagatcaacatgctgctgaacttcagtacgggggaggactgcccttgtcca gaggagatccaggaggagctctacaagttccacaacgagctgcggctccactgcggtatc cccatggaagaggaggaggaggagccagacctgaccatccggggccgactgatggctctg gtgtacaagatcaaaggccaccctcagaagactgagcaggagccgaaagagaaggagctc gctgcccccacaaacctgaaggagctgatctcccagaccatggtgtgctgggcccaggag agccacatccaggaccccgagctggtgcgcgtgatgttcagcctgctgcggcggcagtac gacagcatcggggagctgctgcgcgccatgcgcaagagctacaccatcagcgcctcctct gtgctggacaccatccacctgctggcctcgctcggacagatccgctcactgctcagcgtg cgcatgggcaaggaggaggagcagctcatgatcgacggcctgggggacatcatgaacaac aaggtgttctaccagcatcccaacctgatgcgagtgctggggatgcacgagaccgtcatg gaggtcatggtcaatgtgctggggggagggaaatctcaggagattgcattccccaagatg gtggccagctgttgccgttttctctgctacttctgtcgcatcagccggcagaaccagaag gccatgtttgaccacctcagctatctgctggagaacagcagtgttggcctggcttctccc tctatgaggggatccactcccttggatgtcgctgcctcctcagtgatggacaacaatggt ttggccctagccctagaggagcctgatctagataaggtggtgacgtacctggccggctgt ggtctgcagagctgccccatcctgctggccaagggctaccccgacattggctggaaccct atcgagggggagcgctacctctctttcctccgattcgctgtgtttgtaaatggagagagc gtggaggagaactccagtgtggttgtgaagctgctgattcgccggccggagtgttttggc ccagcgctgagaggggagggggggaacgggctgctggcggccatgaaggaggccataaag atctcggagagcccggcgctggacctgcccagtgctgcccagggcatcagctctgacgcg tcgactgaggatgatgaggaggaagaggtggtgcacatgggcaatgccatcatgtctttc tactcggccctcattgacctgctggggcgctgtgcaccagagatgcacctcattaacaag ggcaaaggtgaagccctgaggatccgtgccatccttcgatcgctggtgcccaccgaagac ttggttggcatcatcagcatacccctcaagatgcctattataaacaaagatggtactgtg acagagccagacatgtcagccagtttctgtccggatcacaaggcaccaatggttctgttc ctggaccgtgtgtacggcatcgaggaccaggccttcctgctccacctgctggaggtgggc ttcctgccggacctacgcgcctctgcaacactcgacacggacaccctgcgcaccactgag acggccctggccatgaaccggtacattggctcggccatgctgcccctgctgacccgctgt gcgccccactttgcgggcactgagcaccacgccgccctcatcgactccaccctgcacacc atctaccgcctctccaagggccgctccctcaccaaggcccagagggacgccatcgaggag tgcctgctggccatctgcaaatacctgaggccctctatgctgcagcagctgttgaggcgt ctggtgtttgacgtgccactgctgacggaatactgcaagatgcctctcaagttgctgacc aaccactacgagcagaactggaagtactactgcctgccgtccgggtcaggaaactacgga atggcttcagaagaggagctcctgctcaccaaaaagatcttctggggcatcttcgactca ctctcgcagaagaagtatgaccaggatctgtttaagatggccatgccctgcctaagtgcc atcgccggagccttaccccctgactacgtggactcgtctctgagcaacaccagcctggag aagacctcgtctgtagaccaacagggcaactttgaccccaaacccatcagcaccgccaac atctctattccagagaaactggagtatgttgccaacaaatacgctgagcattgtcacgac aaatggtctgctgagaaggttctgctgggatggaaatatggggatggcatcgacgagaaa gccaagattcatcacttactgaggtcctacaaatccctcactgagaaggagaaggagatt taccgctggcctgtgcgagagtctctgaagagcatgctggccatgggctggaacattgac cgcaccaaggagggtgagacaatgtcccagcagagtgagaaactccgcaaggcctcacag gggaatggcttcaacccgagcccactggacatgagcaccgtccttctgtccagagagctc cagggtatggtggaggtggtggctgaaaactaccacaacatctgggccaagaagaaaaaa agtgacctgggaagcaggggagggggaacacaccctctgctggtgccttatgatacactt actgcaaaggagaaagccaaagaccgagagaaagcccaggacctgttccgcttcctgcag atcaatggctactccatcaccaggggcttgaaagacatggagcaggatagctcgtccatg gagaagaggtttgcctacaagttcgtcaagaagctgctcaagtatgtggactctgcacag gagttcattgctcacctcgaggccatggccatgagtgggaagatggatagatcacctcat gagcaagaaatcaagttttttgccaaggtcctcctcccgctcattgaccagtactttaag aaccactgtttctacttcctgtcctcccccagtaagaacctcagcagcagtggctacgcc tccaacaaagagaaggagatggtcaccagcctattctgtaaactggcagctcttgtcaga cacaggatctctctgtttggtagtgatgcggccaccatggttagctgtttgcacattctg gctcacactctggacaccagaaccgtgatgaagtcgggttctgagttagtgaaggcaggc atgtggacgttcttcgagaatgcagcagaggacctggagaagacgctggagaacttgaag cttgggaagttcacccactcccgtagccagatgaagggtgtatcgcagaacatcaactac accacggtggccctgctgcccatcctcaccgccctgtttgagcacatcaccgaacaccac tttggagtggacctcctgttggacgatgtccaggtgtcctgttatcgtatcctgaccagc ctgtactccctgggaactggcaagaacatttatgttgagagacagctgcccgctctgggg gagtgtttggcgacgctggcaggagccatgcctgtggccttcctggagccgcagctgaac acacacaacccctgctctgtgttcaacaccaaaacaccacgagagcgcgccatcctgggg atgccggacactgtggaggacatgtgctcagagatcccacgtctgggcggcctgatgaag gacatcaatgatctgtcggagtcgggggcgcgctacacagagatgccccacgtcatcgag gtggtactgcccatgctgtgcaactacctgtcctactggtgggagcgcgggccggagaac caggccgccaccctcaagagtggcgcaggacccatctgctgtgccaccgtcacctcagag cacctgagcgtcatcctgggcaacatcctcaagatcctcaacagcaacctgggcatcgat gaggcctcatggatgaagaggatcgcagtgtacgcccagcccatcatcagcaaggcgcgt gcagacctcttgaagacccacttcctgcccacgctggacaagctgaagaagaagacggtg aaggtggtgaccgaggaggagcttctgaaggctgacagcaagggggacacccaggaggcc gagctgctcatcctggatgagtttgctgtactgtgccgtgacctctatgctttctacccc atgctcatacgttatgtggacaacaacagatccagatggctgaaggagccggatgcagac tccaacgagctctttaggatggtggctgagatctttattctctggtgcaaatcacataat ttcaaacgggaggagcaaaactttgtggtgcagaatgagatcaacaacctctcgttcctc acgggtgacagcaaaactaagatgtcaaagtctggaggtcaggaccaggagcgcaagcac aagaagcggcggggcgagttctactccatccagacctccctgatcgtggctgccctcaag aagatgctgcccatcggcctcaacatgtgcacgcctggtgaccaggagctcatctcactg gccaagaccagatacagcctgaaagacacggatgacgaggtcaaggatcacatacgacac aacctccacctgcaggagaagtcagaggacccggcagtcaggtggcagctgaacctttac aaggacgtggtggtcaggaacgaggggcctcctgacccggagcggacggttgcccgtgtc cagggcctgtctgcagctgtctttcacctggagcaggtggagcagccactgaggtctaag aagtgtgtatggcagaagctcctctctaagcagcgcaagcgtgcggtggtggcctgcttc cgtatggctcccctctacaacctgcccaggcatcgctctattaatctcttccttttgggc tatcaaagaatttggatagagacagagacctactcctttgaggagaaactagtgcaggac ttggcaaaaacacaggtgaaactggaggaagaggaggaggtggaagcagagaagcagcca gatcctctccatcagctcatcctgcattttagccataatgccctcacagagcggagttct ttagatgaggaccctctgtatatggcatacgcagacatgatggcaaagagctgtgcagaa gatggagaagaggaggagggagagggcaagtcgtttgaggaaaaggagatggagaaacag aagacgttgtaccaacaggccagactgcatgacagaggggccgctgagatggttttgcag atgatcagtgccagcaagggtcgattggatcccatggtgacgtacactcttaaattaggc atctccatcctcaacggtggcaacattatcgtccagcagaaaatgctggattacctgaag gagaaaagggacgttggcttcttcaagagcttatctggactcatgcagtcatgcagtgtc ttggatttgaatgcctttgagagacagaataaagccgaaggtttgggcatggtgactgag gaaggatcaagttccaaggttcttcagaacgatgaattcacaaaggatctgtttaggttc cttcagctgctgtgtgagggccacaacaacgacttccagaatttcctgcggactcagact ggaaatacaaccacagtgaatattatcatcagcactgtggactacttacttcgattgcag gaatcaatcagtgatttctattggtactactctgggaaggatgtcatggacgaggctggc cagagaaacttctccaaagccctggcagtggccaagcagatcttcaactccctcacagag tacatacagggtccatgtataggaaaccagcagagtctggctcacagcaggttgtgggat gcagtggtgggattcctccatgtgtttgccaacatgcagatgaagttgtcacaggactcg agccagatagagttactgaaagagctgatggatctgcagaaggacatgattgtcatgatg ctatctcttctggaaggtaatgtggtgaatgggaccattgggaaacagatggtggacaca cttgtggagtcgtccagtaacgtggaaatgatcctcaagttcttcgacatgttccttaaa ttaaaggacctaactacctcagacaatttcaaggagtatgaccccgacagcaaaggggcc atctctaagaaggagttccagaagtccatggagaaccagaagcagtactcgcagtcagag atcgagttcctcctctcatgcgtcaaggccgacgagaacgacatgttcaactacgaggag ttcgtagagcgcttccatgagcctgccaaggacatcggcttcaacgtggccgtgttgctc acaaatctctcggagcacatgccccacgatggccgcctggccgccttcctggacctgggc gagagcctgctgagttactttgagccgtacctcggccgcatcgagatcctgggcagcggc aagcgcatcgagcgcgtctacttcgagatcagcgagtcaagccgcacgcagtgggagaaa ccacaggtgaaggagtccaaacggcagttcatcttcgacgtggtcaacgagggtggtgag agcgagaagatggagctctttgtcaacttctgcgaggacacaatcttcgagatgcagctg gcctcgcagatctccgagcccgacgccctcgagcgtcctgaggaggacgaggaggacgac gtggccagtgtggccgaggaggccgacgaggacgacgaagacaatgccctggagtcctcc tctgcatttgccgttgcctgcgtctccatgaagaagagcttctcgggcttctggaaactt ctgactttcaagagcatgcgccggcagtacaagcgcttccggaagatgagcgtgcgggag atggtgcgtggcttcttctccttcttctgggtgatcttcaccggcctcttccgctttctc tacagcctcgtctggggcttcttccacatcctgtggagctccatgttcggtggtggcctg gtggagggtgccaagaacatgaaggtgacggacatcctgggcaatatgcccgaccccacg cagttcggcatccacggcgatgtgctggaggccgagaagatggaagcgtgcgagggggcg ctctcggtgactgagatggagcagaacgctgctgctgaccaggctgaggccgacctcatg gccgagctgctcaacatccagcccaagaaggaggggggcaagcacgtggagccagggctg ggtgatgtctctgaggtagtgggggtggacgccccatccatagcagcagctgtgaggcag aagaaggctcagaaggaggctgctcataagaaggcagaggcagaggccgagagagaacag agagaaggagagaagacagacctggaggacggggagaagaaggacctggacaagaacaga gatgagacccccccaaacacacctgcagaggaggagaggaggctccccaagaagcgcccc cggcagaaggaggagccaccagaggcgttcatggccagcttctttgcaggccttgaaatc taccagacaaagatgctgaactatctggcaaggaacttttacaacctccgtttcttggcc ttgtttgtggctttcgctatcaacttcattctgctgttctataaggtaatatggcactct aattcagtcacactttacttgtatgaggaggacccgtggaacgggggccaggtggaggag gaggagggggcgatggagtactttgtcctgcaggagagcacaggctacatggcccccacg ctgcgctttctggctgtgctgcacaccctcatctctttcctatgcgtggtgggatactac tatctcaaggtgcctttggtggtgttcaagagggagaaagagatcgccaggaagctggag ttcgatggcctctacatcactgagcagccctcggacgacgacatcaaaggacagtgggac cggctggtcatcaacacaccatccttcccaaacaactactgggataagtttgtcaaacgc aaggtgatcaataagtacggggatctgtatggtgctgagcgcattgctgagctgctgggc ctggataagagtgcgcttgacttcaaccctacagaggaggccgtggtgaaggaggcatca ctcgtctcctggctgagctccattgacaccaaatatcatatctggaaattgggagtggtc ttcacagacaattctttcctgtaccttgtgtggtacaccaccatgtctattctaggacac tacaacaacttcttctttgctgctcatctgctggacatcgccatgggcttcaagacgctc aggaccatcctctcctcagtcacccacaatggcaaacagctggtgttgacggtggggctg ttggctgtggtggtgtacctctacactgtggtggccttcaactttttccgcaagttttac aacaagagtgaggatgaggatgagccagacatgaagtgtgatgacatgatgacctgctac ttgttccacatgtatgtgggtgtgcgtgccggagggggcattggtgacgaaatcgaggac ccggcgggtgacccttacgagctctaccgcatcctcttcgacatcaccttcttcttcttc gtcatcgttatcctcctggccatcatccagggtttgatcattgatgcttttggggaactg agagaccaacaggaacaggtgaaagaggacatggagacaaagtgcttcatctgtggaatc ggcaatgactactttgacacgacgccccacggctttgagacccacacgttgcaagagcac aacttggctaactatctgttcttcctgatgtacataatcaacaaggatgaaactgagcac acaggacaagagtcatatgtttggaagatgtaccaggagagatgctgggacttcttccca gctggagactgcttcaggaaacagtatgaggaccagctaggctaa

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