KEGG   Spirillospora sp. NBC_01491: OHA34_10720
Entry
OHA34_10720       CDS       T09711                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
spiq  Spirillospora sp. NBC_01491
Pathway
spiq00290  Valine, leucine and isoleucine biosynthesis
spiq00620  Pyruvate metabolism
spiq01100  Metabolic pathways
spiq01110  Biosynthesis of secondary metabolites
spiq01210  2-Oxocarboxylic acid metabolism
spiq01230  Biosynthesis of amino acids
Module
spiq_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:spiq00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    OHA34_10720 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    OHA34_10720 (leuA)
Enzymes [BR:spiq01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     OHA34_10720 (leuA)
Motif
Pfam: HMGL-like LeuA_dimer
Other DBs
NCBI-ProteinID: WUU93891
LinkDB
Position
2266537..2268225
AA seq 562 aa
MPFHRYRPVFERVRVPEIDRTWPSARIETAPLWVPVDLRDGNQALAEPMDPARKRRMFDL
FTAMGFKEIEVGYPSASRADFDFVRHLAESGAVPDDVTVVVFTPARRDLIERTFASIGGL
PRVVVHMYTATAPVWREVVLGRDRADLHALIRDAAGQVARLAGGRAGVRFEFSPEVFMLT
EPDFALEVCDGLTALWDASPDRPVIHNLPVTVEVATPNVYADQIEYMHRHLARRDSVILS
VHPHNDRGTGVACAELAVLAGAQRVEGCLFGNGERTGNVDLVTLALNLHAQGVDPRIDLS
DIDEIRRTVEHCNRLPVHERHPYGGDLVYTAFSGTHQDAISKGMAHHAERAAALGVPAGQ
APWNVPYLPIDPGDVGRDYEAVIRVNSQSGKGGIAYLLRTGHGLDLPRRLQIEFSEVVQR
ATDDSGEEVSGKELWELFRAEYLDRADDGPVTLAGWRTGHTGPGRHDFTGVLRIDGREAE
HTGSGNGPLDALTGALAAAGTAVDVLQYVEHATAAGRDAPAVAYAECRVDGVTRWGAGRD
TSILTASVRAVLSAVNRAKRPA
NT seq 1689 nt   +upstreamnt  +downstreamnt
atgcccttccaccgctaccggcccgtgttcgagcgggtgcgggtgcccgagatcgaccgc
acctggccgtccgcccgcatcgagaccgccccgctgtgggtgccggtcgacctgcgcgac
ggcaaccaggcgctggccgaaccgatggaccccgcccgcaagcgccggatgttcgacctg
ttcacggccatgggcttcaaggagatcgaggtcggctacccctcggccagccgggccgac
ttcgacttcgtccggcacctggccgagtccggcgcggtgccggacgacgtcaccgtcgtg
gtcttcacccccgctcgccgcgacctgatcgagcggaccttcgcctcgatcgggggcctg
ccccgggtggtggtgcacatgtacaccgcgacggccccggtctggcgcgaggtcgtcctc
ggccgcgaccgcgcggacctgcacgcgctgatcagggacgcggccgggcaggtggcccgg
ctggcgggcggccgggcgggcgtccggttcgagttctcgcccgaggtcttcatgctcacc
gagccggacttcgcgctggaggtgtgcgacgggctgaccgcgctgtgggacgcctccccg
gaccgcccggtgatccacaacctgccggtcaccgtcgaggtcgccacccccaacgtgtac
gccgaccagatcgagtacatgcaccgccacctcgcccggcgcgactcggtgatcctctcg
gtgcacccgcacaacgaccgcggcaccggtgtcgcctgcgccgagctggcggtgctggcc
ggggcgcagcgggtcgagggctgcctgttcggcaacggcgagcgcaccggcaacgtcgac
ctggtcacgctcgccctcaacctgcacgcgcagggcgtggacccgcggatcgacctctcc
gacatcgacgagatccgccggacggtcgagcactgcaaccggctgccggtgcacgagcgc
cacccctacggcggcgacctcgtctacaccgcgttctccgggacgcaccaggacgcgatc
agcaagggcatggcgcaccacgccgagcgggccgccgcgctcggcgtcccggccggtcag
gccccgtggaacgtcccgtacctgccgatcgaccccggggacgtgggccgcgactacgag
gcggtcatccgggtcaacagccagtccggtaagggcgggatcgcctacttgctgcgcacc
ggccacggcctggacctgccccgccgcctccagatcgagttctccgaggtggtgcagcgc
gccaccgacgacagcggcgaggaggtgagcggcaaggagctgtgggagctgttccgcgcc
gagtacctggaccgcgcggacgacggcccggtgacgctggccgggtggcggacgggccac
accgggcccggccgccacgacttcaccggcgtcctgcggatcgacgggcgggaggccgag
cacaccggttcgggcaacggcccgctggacgcgctgaccggcgcgctcgccgccgccggg
acggcggtggacgtcctccagtacgtcgagcacgcgaccgcggccgggcgggacgccccc
gccgtcgcctacgccgaatgccgcgtcgacggcgtcacccgctggggcgcgggccgggac
acctcgatcctcaccgcgtccgtccgcgccgtcctgtcggccgtcaaccgcgcgaagcgt
cccgcctga

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