Streptococcus pyogenes MGAS2096 (serotype M12): MGAS2096_Spy0894
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Entry
MGAS2096_Spy0894 CDS
T00357
Symbol
folC1
Name
(GenBank) Folylpolyglutamate synthase / Dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
spj
Streptococcus pyogenes MGAS2096 (serotype M12)
Pathway
spj00790
Folate biosynthesis
spj01100
Metabolic pathways
spj01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
spj00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
MGAS2096_Spy0894 (folC1)
Enzymes [BR:
spj01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
MGAS2096_Spy0894 (folC1)
6.3.2.17 tetrahydrofolate synthase
MGAS2096_Spy0894 (folC1)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
ABF35946
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Position
859706..861082
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AA seq
458 aa
AA seq
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MFGEDNKKKGTTLGYLLSLFFIYGILKIDVRCEMTYEETLEWIHDHLVFGIKPGLKRMLW
VLGQLGNPQKNVKGVHIVGTNGKGSTVNHLQHIFTTAGYEVGTFTSPYIMDFKERISING
RMISEKDLVIAANRIRPLTERLVQETDFGEVTEFEVITLIMFLYFGDMHPVDIAIIEAGL
GGLYDSTNVFQAMVVVCPSIGLDHQAILGETYADIAAQKAGVLEGGETLVFAVENPSARE
VFLTKAEQVGASIWEWQEQFQMAENASGYRFTSPLGVISDIHIAMPGHHQVSNAALAIMT
CLTLKDRYPRLTSDHIREGLANSLWLGRTELLAPNLMIDGAHNNESVAALVAVLKNNYND
KKLHILFGAIDTKPIADMLVALEQIGDLQVTGFHYPNAYPLEKYPERFGRVADFKDFLAL
RKHAKADDFFVITGSLYFISEIRQYWKKHIEKNVLLTH
NT seq
1377 nt
NT seq
+upstream
nt +downstream
nt
gtgtttggtgaggataataaaaaaaagggtactactctaggttatctgctgtcacttttt
tttatatatggtatactaaagatagatgtgaggtgtgaaatgacttatgaagagactcta
gaatggattcatgatcacttagttttcggcatcaagccaggcttaaaacgtatgctttgg
gttcttggacagttaggaaatccccaaaaaaatgtcaagggagtgcatatcgttggaact
aacggaaaaggttccacggtcaatcatttacaacacatttttacgacagctggttatgaa
gtggggacctttacctctccttatattatggatttcaaagaacgtattagcataaatggt
cgaatgatttcagaaaaagatttggttattgctgctaatcgtattcgtcctttgacagag
cgtctagttcaagagactgattttggagaggtaactgaatttgaagtgattactttgatc
atgttcctctattttggagacatgcatcctgtagatattgctattattgaagcaggcctt
ggcggtctttatgattcgaccaatgtttttcaagcaatggttgtggtatgtccctcaatt
ggtttagatcaccaagctattttgggagagacttacgctgatattgccgcccaaaaagct
ggtgttttagaagggggcgagacccttgtttttgccgttgaaaacccgtcagctcgagag
gtttttttaacaaaagctgagcaggttggtgcttcaatctgggaatggcaagagcagttt
caaatggctgagaacgcatctggctatcgttttactagtcctttaggagttatttcagat
attcacatcgctatgccaggacaccaccaagtgtctaatgcagctttagctattatgact
tgcttaaccttgaaagaccgctatcctaggctaacttcagatcatataagggaaggtctg
gcaaatagtttgtggctaggccgtaccgaattattagcaccaaatctaatgattgatggg
gctcataacaatgaaagcgttgctgctttggtagccgtcttaaaaaataactacaatgat
aaaaagcttcatattttgtttggtgcgatcgacaccaagcctattgcggatatgttggtt
gctcttgagcaaataggtgacttgcaggttactggctttcattaccctaacgcctatcca
ttggaaaaatacccagaacgttttggtagggttgctgatttcaaagatttcttggccctg
cgtaagcatgccaaagcagatgactttttcgtgattacagggtcgctatattttatttca
gaaattagacagtattggaaaaaacatattgaaaaaaacgttcttttaacccattaa
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