Streptococcus pyogenes MGAS9429 (serotype M12): MGAS9429_Spy0025
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Entry
MGAS9429_Spy0025 CDS
T00358
Symbol
purM
Name
(GenBank) phosphoribosylformylglycinamidine cyclo-ligase
KO
K01933
phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.3.1
]
Organism
spk
Streptococcus pyogenes MGAS9429 (serotype M12)
Pathway
spk00230
Purine metabolism
spk01100
Metabolic pathways
spk01110
Biosynthesis of secondary metabolites
Module
spk_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
spk00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
MGAS9429_Spy0025 (purM)
Enzymes [BR:
spk01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
MGAS9429_Spy0025 (purM)
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GFIT
Motif
Pfam:
AIRS_C
AIRS
Motif
Other DBs
NCBI-ProteinID:
ABF31213
UniProt:
Q1JP36
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Position
41887..42936
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AA seq
349 aa
AA seq
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MSEKNAYAKSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFGGMFDLSKTGVREPVLV
SGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPLEPLYFLEPLYFLDYVATG
KNNPVKFEEVVSGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAVGVAEKSQLIDG
SKVKEGDILLGLASSGIHSNGYSLVRRVFADYTGKELLPELEGKQLKDVLLEPTRIYVRA
ALPLIKEELVNGIGHITGGGFIENVPRMFADDLAAEIDEDKVPVLPIFKALEKYGDIKHE
EMFEIFNMGVGLMLAVSPENVNRVKELLDEPVYEIGRIIKKADDSVVIK
NT seq
1050 nt
NT seq
+upstream
nt +downstream
nt
atgtctgaaaaaaatgcttatgcaaaatctggtgttgatgttgaagctggttatgaagtg
gttgaaagaataaaaaaacacgttgctcgtacagaacgtgcgggagtcatgggagctcta
ggtggctttggtgggatgtttgacttgagtaaaacaggagttagagagcctgttttggtc
tcagggacagacggtgttggcacaaaactcatgcttgctatcaagtacgacaagcacgac
acaatcggtcaagactgtgttgccatgtgtgtcaatgatattattgcagcaggtgctgag
ccccttgagcccctttacttccttgagcccctttacttccttgactacgtagcgacagga
aaaaataatccagtcaaatttgaagaagttgtttctggcgttgcagaaggttgtgttcaa
gcaggagcagcactcattggaggtgagaccgctgaaatgcctgggatgtatggcgaagat
gattatgaccttgctggctttgctgttggtgtggctgaaaaatctcagctcatcgacggt
tcaaaagtaaaggaaggcgatattcttttgggacttgcttcaagtggtatccattcaaac
ggttattctttggtacgtcgtgtctttgctgactatactggtaaagagctgcttccagaa
cttgaaggaaaacaacttaaggatgtccttcttgagccaactcgtatttatgttagagca
gctctgccattaatcaaggaagaactagtcaacggtatcggccacatcacaggtggtggc
tttatcgagaatgttcctcgtatgtttgcagatgatttggctgcggaaatcgatgaggac
aaggtgccagtgcttccgattttcaaggcgcttgaaaaatatggtgacatcaagcacgaa
gaaatgtttgaaatcttcaatatgggtgtcggtcttatgctagctgttagtcctgaaaat
gttaaccgcgtcaaagagctcttggatgaaccagtttatgaaatcggtcgtatcatcaag
aaagcagacgatagtgtggtgattaaataa
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