Streptococcus pyogenes MGAS9429 (serotype M12): MGAS9429_Spy0683
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Entry
MGAS9429_Spy0683 CDS
T00358
Symbol
folC2
Name
(GenBank) folylpolyglutamate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
spk
Streptococcus pyogenes MGAS9429 (serotype M12)
Pathway
spk00790
Folate biosynthesis
spk01100
Metabolic pathways
spk01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
spk00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
MGAS9429_Spy0683 (folC2)
Enzymes [BR:
spk01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
MGAS9429_Spy0683 (folC2)
6.3.2.17 tetrahydrofolate synthase
MGAS9429_Spy0683 (folC2)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
ABF31871
UniProt:
Q1JME1
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All DBs
Position
complement(669083..670375)
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AA seq
430 aa
AA seq
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MLEGQEIVMTTYDSISWIHTFKANGRKTDLARMAWLLEALGRPQDKFPAIHVVGTNGKGS
VTAYLQHILSTSGYQVGTFTSPFIISFHDRICLNGQPISDLELAQCVSVIRPILTKMSLE
TNWDRPTEFELVTLIMFCYFANLKPVDIAIIEAGIGGKTDATNVFHALAVVCPSISFDHQ
ERLGYSLAEIAHQKAEVIKAKEPVIIGQLEQEASQVFQQVTQKAGSRLYQLGKDFLLNPS
EKTFSFQHDNLNLTKLRLKLLGQHQKANACLAIMTAQLLRKSFPKISPKTIQKGIEATTW
PGRSEFIQPNLLLDGAHNPDSIAKLKSLLQEEFPKRPIHILFAGLKRKPLADLLAQLDTF
EVSVTTFDFPEANLLEDYPDKYPQVKDYRDWLQGSVTSDELFVVTGSLYFISEVRQYCLS
NANIFKNIFP
NT seq
1293 nt
NT seq
+upstream
nt +downstream
nt
ttgttagaaggacaagaaatagtaatgactacctatgatagcatttcctggattcatacc
tttaaggctaatggtcgcaagaccgatttggccagaatggcttggttacttgaggcacta
ggccggccacaagacaaattccctgctattcacgttgttggaactaacggcaagggctct
gtgacagcctacttacagcatatcctgtcaacttctggttatcaggtcggaacctttaca
tctccttttattatctcttttcacgatcggatttgccttaatggccagcccatttcagac
ctagaattggcgcaatgtgtgagcgtgattagacccattctcactaaaatgtcccttgaa
acaaattgggatagacctaccgagtttgagttagtgacgctcataatgttttgctacttt
gccaatcttaaacctgttgatattgccattattgaggcagggattggtgggaaaaccgac
gcaaccaatgtttttcatgctctggccgtcgtatgcccttctattagttttgatcaccaa
gaacgtttaggttatagcctagcagaaattgctcaccaaaaagcagaagttatcaaagct
aaagaacccgttattatcggtcaacttgagcaggaggctagtcaagtctttcaacaagtt
acccaaaaagccggttcacgcttatatcaattaggaaaagattttttgctcaatccttca
gaaaagacgttttcctttcaacacgataacttgaatttaaccaaactccgtctcaaacta
ttaggtcaacatcaaaaagcgaatgcctgtttagccattatgacagctcaattacttaga
aaatcctttcctaaaatatctccaaaaacgattcaaaaaggaattgaggcaacaacttgg
cctggccggtccgaatttattcaacctaatcttctattagacggcgctcacaatccagat
tccattgctaaattaaagtctctactgcaagaagaatttcccaaacgtcctattcatatt
ctctttgcaggtctcaaacgtaagcctttagccgacttgctggctcaactagatactttt
gaagtatctgtcacgacttttgatttccctgaagcaaatcttttagaggattatcctgat
aaatacccacaggtaaaagattacagagactggttacaaggttccgtaacatctgatgaa
ctctttgttgttacagggtcactttattttatctccgaggtaaggcaatattgtctgagc
aacgcaaatatctttaaaaacatattcccctaa
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