Streptococcus pyogenes MGAS9429 (serotype M12): MGAS9429_Spy0867
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Entry
MGAS9429_Spy0867 CDS
T00358
Symbol
acoC
Name
(GenBank) dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KO
K00627
pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:
2.3.1.12
]
Organism
spk
Streptococcus pyogenes MGAS9429 (serotype M12)
Pathway
spk00010
Glycolysis / Gluconeogenesis
spk00020
Citrate cycle (TCA cycle)
spk00620
Pyruvate metabolism
spk00785
Lipoic acid metabolism
spk01100
Metabolic pathways
spk01110
Biosynthesis of secondary metabolites
spk01120
Microbial metabolism in diverse environments
spk01200
Carbon metabolism
spk01210
2-Oxocarboxylic acid metabolism
Module
spk_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
spk00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
MGAS9429_Spy0867 (acoC)
00020 Citrate cycle (TCA cycle)
MGAS9429_Spy0867 (acoC)
00620 Pyruvate metabolism
MGAS9429_Spy0867 (acoC)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MGAS9429_Spy0867 (acoC)
Enzymes [BR:
spk01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.12 dihydrolipoyllysine-residue acetyltransferase
MGAS9429_Spy0867 (acoC)
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Motif
Pfam:
2-oxoacid_dh
E3_binding
Biotin_lipoyl
Biotin_lipoyl_2
PYNP_C
PLA2_B
Motif
Other DBs
NCBI-ProteinID:
ABF32055
UniProt:
Q1JM14
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All DBs
Position
834572..835981
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AA seq
469 aa
AA seq
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MAFEIIMPKLGVDMQEGEIIEWKKQEGDTVNEGDILLEIMSDKTNMELEAEDSGVLLKIV
RPAGDTVPVTEVIGYIGAEGESVDTIASSEKTTEIPVPASADAGPTVAPKENVASPAPQV
AATAIPQGNGGKVRATPAARKAAAEMGIDLGQVPGTGPKGRVHKEDVENFKGAQPKASPL
ARKIAADKGIDLATVSGTGFNGKVMKEDIKAILEAAKPAEAKAPAAKEEKVVDLPEGVEH
KPMSAMRKAISKGMTNSYLTAPTFTLNYDIDMTEMIALRKKLIDPIMAKTGLKVSFTDLI
GMAVVKTLMKPEHEYMNASLINDANDIELHRFVNLGIAVGLDDGLIVPVIHGADKMSLSD
FVLASKDVIKKAQTGKLKAAEMSGSTFSITNLGMFGTKTFNPIINQPNSAILGVGATIPT
PTVVDGEIVARPIMAMCLTIDHRLVDGMNGAKFMVDLKKLMENPFELLI
NT seq
1410 nt
NT seq
+upstream
nt +downstream
nt
atggcatttgaaattattatgccaaagctgggcgttgacatgcaagaaggcgagatcatc
gagtggaaaaaacaagaaggtgataccgtcaatgaaggtgatatccttcttgaaatcatg
tcagacaaaaccaatatggaacttgaggcagaagactcaggtgtgctattgaaaattgtc
cgtccagctggtgatactgtacctgtaactgaagttatcggttacattggtgcagagggt
gaatcagtagatactattgcttcaagtgaaaaaacaacagaaattccagttcctgcttca
gcagatgctggaccaacagttgctccaaaagaaaatgtggcaagtccagctcctcaagtg
gcagcgacagctattccgcaaggaaatggcggaaaagttcgtgctactccagctgcacgt
aaggcagcagcagaaatgggcattgaccttggccaagttccaggaacaggaccaaaagga
cgtgtccataaagaagacgttgaaaactttaaaggtgctcaaccgaaagcttcaccactt
gctcgtaaaattgcagcagacaaaggtattgatttggcaaccgtatcaggtactggcttt
aacggtaaggtcatgaaagaagacatcaaggctattcttgaagcggctaaaccagctgaa
gcaaaagcaccagcagctaaagaagaaaaagttgttgaccttccagaaggtgtggaacac
aagccaatgtcagctatgcgtaaggcaatctctaaaggtatgacaaactcttaccttact
gcgcctacctttacgcttaactacgatattgacatgacagagatgattgcccttcgtaag
aagttaattgacccaatcatggctaaaacaggccttaaagtcagctttacagacttgatt
ggtatggcagtggttaaaaccttgatgaaacctgagcatgagtacatgaatgcttccctc
atcaatgatgctaatgatattgaattgcaccgctttgtgaaccttggtattgccgtaggt
cttgatgatggtcttatcgttcctgttatccatggggctgacaagatgagcttgtcagat
ttcgtgcttgcttcaaaagatgtgattaaaaaagcgcaaactggtaagttgaaagcagcc
gaaatgtctggatcaaccttctctatcacaaacttgggaatgtttggtacgaagacattt
aacccaattattaaccaaccaaactcagcaattcttggtgttggagcaactatcccaact
ccaacggttgtggatggtgagattgttgcccgtccaattatggcaatgtgcctaaccatc
gaccaccgtttagttgatggtatgaacggtgcaaaattcatggttgatctcaagaaattg
atggaaaatccatttgaattgttaatctga
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