Streptococcus pyogenes MGAS9429 (serotype M12): MGAS9429_Spy1030
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Entry
MGAS9429_Spy1030 CDS
T00358
Symbol
fhs1
Name
(GenBank) formate--tetrahydrofolate ligase
KO
K01938
formate--tetrahydrofolate ligase [EC:
6.3.4.3
]
Organism
spk
Streptococcus pyogenes MGAS9429 (serotype M12)
Pathway
spk00670
One carbon pool by folate
spk00720
Other carbon fixation pathways
spk01100
Metabolic pathways
spk01120
Microbial metabolism in diverse environments
spk01200
Carbon metabolism
spk01240
Biosynthesis of cofactors
Module
spk_M00140
C1-unit interconversion, prokaryotes
Brite
KEGG Orthology (KO) [BR:
spk00001
]
09100 Metabolism
09102 Energy metabolism
00720 Other carbon fixation pathways
MGAS9429_Spy1030 (fhs1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
MGAS9429_Spy1030 (fhs1)
Enzymes [BR:
spk01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.3 formate---tetrahydrofolate ligase
MGAS9429_Spy1030 (fhs1)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
FTHFS
CbiA
DUF719
Motif
Other DBs
NCBI-ProteinID:
ABF32217
UniProt:
Q1JLK2
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All DBs
Position
complement(987911..989581)
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AA seq
556 aa
AA seq
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MKSDIEIAQSVALQPITDIVKKVGIDGDDIELYGKYKAKLSFEKMKAVEANEPGKLILVT
AINPTPAGEGKSTMSIGLADALNQMGKKTMLALREPSLGPVMGIKGGAAGGGYAQVLPME
DINLHFTGDMHAITTANNALSALIDNHLQQGNDLGIDPRRIIWKRVLDLNDRALRQVIVG
LGSPVNGVPREDGFDITVASEIMAILCLATDLKDLKKRLADIVVAYTYDRKPVYVRDLKV
EGALTLILKDAIKPNLVQTIYGTPALIHGGPFANIAHGCNSVLATSTALRLADYTVTEAG
FGADLGAEKFLNIKVPNLPKAPDAIVIVATLRALKMHGGVAKSDLAAENCEAVRLGFANL
KRHVENMRQFKVPVVVAINEFVADTEAEIATLKALCEEIKVPVELASVWANGAEGGLALA
KTVVRVIDQEAADYKRLYSDEDTLEEKVINIVTQIYGGKAVQFGPKAKTQLKQFAEFGWD
KLPVCMAKTQYSFSDNPSLLGAPTDFDITIREFVPKTGAGFIVGLTGDVMTMPGLPKVPA
AMAMDVAENGTALGLF
NT seq
1671 nt
NT seq
+upstream
nt +downstream
nt
atgaaatcagatatcgaaattgcccaaagtgtcgccctacaaccaatcactgacattgtt
aaaaaagttggaatagacggcgatgacattgagctttatggcaaatataaggctaaattg
tcttttgagaaaatgaaagctgtcgaagctaatgagcctggaaaattaatcttggtaact
gctattaaccctactccagcaggagaaggaaaatcaaccatgtctattggactggcagat
gccttaaatcaaatgggaaaaaaaaccatgcttgccttacgtgaaccctcccttggtcct
gttatggggattaaaggcggggcagcaggtggtggttatgcccaagtattgcctatggaa
gacattaatcttcactttactggtgacatgcatgccattacaaccgctaataatgcatta
tctgctttgattgacaatcatttgcagcaaggaaacgatttaggaattgatcctcgccgc
attatttggaagcgcgtgttggaccttaatgatcgtgctcttcgtcaggtaattgttggc
ttaggcagtccagtgaatggtgtgccacgcgaagatgggtttgatatcacagtagcttct
gaaatcatggcaattttatgtttggcaactgacttgaaagatctaaagaaacgtcttgct
gatatcgtcgtggcttatacctatgatcgtaagcctgtctatgtgcgtgacttgaaggtt
gaaggagcattgacattaattctaaaagatgctatcaagccaaacttggtgcagactatt
tatggaacaccagctcttattcatggggggccatttgctaatattgctcatggttgtaat
tctgtccttgctacctcaacagctttgcgattagcagattacactgttaccgaagcagga
ttcggggccgacctaggagctgaaaaattcctaaatatcaaagtacctaatcttcctaaa
gcaccagatgctatcgtcattgttgcaaccttgcgcgcccttaaaatgcatggaggtgtc
gccaaatcagatttagccgctgaaaattgtgaggctgttcgcttaggatttgccaactta
aaacgtcacgtggaaaacatgcgccaattcaaagttccagttgtggtggctatcaatgaa
tttgtagcagataccgaggctgaaattgctaccttaaaagcgctttgtgaagagattaag
gttccagtagaattagccagtgtttgggcaaatggagctgagggaggcttagcattagct
aaaacagtggttcgtgtgattgatcaagaagctgctgactacaaacgtctctattcagat
gaggatactttggaagaaaaagtgatcaatatcgttacccagatttatggtggcaaagct
gttcaatttggccccaaggccaaaacacaattgaagcagttcgcagaattcggttgggat
aaattgcctgtttgtatggctaagacccaatacagtttttcagataacccatccttgctt
ggagcgccaaccgattttgatattaccattcgtgaatttgttcctaaaacaggggcaggt
tttattgttggtttaacaggtgatgtgatgaccatgcctggtttgcctaaagttccagct
gccatggcaatggacgtagcagaaaatggcacagccctcggtctcttttag
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