| Entry |
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| Symbol |
murF
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| Name |
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
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| KO |
| K01929 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] |
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| Organism |
spk Streptococcus pyogenes MGAS9429 (serotype M12)
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| Pathway |
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| Brite |
KEGG Orthology (KO) [BR:spk00001]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
MGAS9429_Spy1204 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
MGAS9429_Spy1204 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
MGAS9429_Spy1204 (murF)
Enzymes [BR:spk01000]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
MGAS9429_Spy1204 (murF)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
complement(1162638..1164029)
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| AA seq |
463 aa
MKLTLHEVAKIVDAQNNVSDLDDVPLHHIEFDSRKITKGDLFLPLKGQRDGHEFIDLAFQ
NGAVATFSEKELPGTPHLLVEDCLKAFQKLAHYYIDKMRVDVIAVTGSNGKTSTKDMIGA
VLSTTYKTYKTQGNYNNEIGLPYTVLHMPDDTEKIVLEMGQDHMGDIRLLSEIARPRIAV
LTLVGEAHLEYFGSRDKIAQGKMQIVDGMNSDGILIAPGDPIIDPYLPENQMVIRFGNQQ
EIDVTGIQEDKDSLTFTTNVLATPVSLPLPGKYNATNAMVAAYVGKLLAVTDEDIIAALQ
TVTLTGNRTEWKKAANGADILSDVYNANPTAMRLILETFANIAKNPGGKKIAVLADMKEL
GKDSVILHSQLIDSLTSGNIDQLVFYGDHIKELARLASQVYPAEQVHYFLKTEQEDQFEA
MAQYVQNILNPFDQILLKGSHSMSLEKLVERLVTDKNCDSYQP |
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| NT seq |
1392 nt +upstreamnt +downstreamnt
atgaaattaaccttacacgaagtggctaaaatagttgacgcccaaaataatgtgtctgac
ttagacgacgttcctctgcatcacattgaatttgatagccgaaagattacaaaaggagac
ctctttttacccttaaaaggtcaaagggatggtcatgagtttattgatttagcctttcaa
aatggagctgtcgctactttttcagaaaaagaattgccggggacacctcaccttcttgtt
gaagactgcctaaaagcttttcaaaagctagcccattattatattgataagatgcgcgtg
gatgttattgctgtgacaggctcaaatggtaaaacttccaccaaagatatgataggagct
gtcctatcaaccacttacaaaacttacaaaacgcaaggaaattacaataatgagattggt
ttgccttacaccgttctccacatgcctgacgatacggaaaaaattgttcttgaaatggga
caagatcacatgggagatattcgtcttctgtctgaaattgcaaggcctcgtattgcagtt
ttaaccttagtcggcgaagctcatttagaatattttggaagccgagacaaaatagcccaa
ggcaaaatgcagattgttgacggcatgaattcagatgggattttaattgctccgggagat
ccgattattgacccatatcttccagaaaatcagatggttatccgttttggaaatcagcag
gaaattgacgttactggtattcaagaagacaaagatagcttaacgtttacaacaaatgtg
ttagcaacacctgtgtccctacctctaccaggaaaatacaacgcgaccaatgctatggta
gcagcctatgtaggaaaactattggcagtaacagacgaggatattatagctgctttacag
actgtgacgttgacaggtaatcgtacggagtggaaaaaagcagccaatggtgctgatatt
ttatcagatgtctacaatgccaacccaacagccatgcgtctgattttagaaacatttgct
aacatagcaaagaaccccggaggaaaaaagattgcagtgctagcagatatgaaagaactt
ggaaaggattcagtgatacttcattctcagttaattgacagcttaacatcaggtaatatt
gatcagcttgttttttatggggatcatattaaagaattagcacggttggcaagtcaggtt
tatcctgctgagcaagtacattattttttaaaaactgaacaagaagaccagtttgaagcc
atggcacaatatgttcaaaacattcttaatccctttgatcaaattcttttaaaaggcagc
cactcgatgtcgctagaaaagttagtggaacgattagtgactgacaagaattgtgacagc
tatcagccttga |
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