Sphingomonas sp. KC8: KC8_09150
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Entry
KC8_09150 CDS
T04987
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
spkc
Sphingomonas sp. KC8
Pathway
spkc00300
Lysine biosynthesis
spkc00550
Peptidoglycan biosynthesis
spkc01100
Metabolic pathways
spkc01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
spkc00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
KC8_09150
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
KC8_09150
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
KC8_09150
Enzymes [BR:
spkc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
KC8_09150
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ARS27455
UniProt:
A0A1X9YF48
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All DBs
Position
complement(1916547..1917950)
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AA seq
467 aa
AA seq
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MTAPLWTAFDIASATDGEVFGDFAAHGVAFDSREVGPGDLFVALKGEATDGHRFVDGAFA
AGAAGAIVSDAVNGPHVRVADTVAALDALGAASRARTNAKIIGVTGSVGKTGTKEALFAA
FDRAAPGAAHRSLKSYNNHVGVPLSLARMPADTRYGVFEMGMSAAGELAALTRLVRPHVA
VVTTIAPAHSAFFASEEAIADAKGEIFQGLEPGGTAIIPFDSPHRDRLIAAARPYAGRIW
TFGRGEGADIRAREAVRGHRGTLIAATLPGAELTFSLAPPGDHWVANAMAVIAAVHAVDG
DLAAAGLALADMAGLAGRGRRVTARVRDGDALVIDESYNANPASMAATIALLGEEKAGRR
IVVLGDMRELGEKSPVYHAALAQPLAQANVDFALLVGPEMAALANELEGRVDFAHVPDAA
AALARIDDLIEAGDAVLIKGSNAIGLARLVEHLGSGAVAAGNKPCSI
NT seq
1404 nt
NT seq
+upstream
nt +downstream
nt
atgaccgcgccactgtggaccgcattcgacatcgcatcggccaccgatggcgaggtgttc
ggggatttcgccgcccatggcgtcgcgttcgattcccgcgaagtggggccgggcgatctg
ttcgtcgcgctgaagggcgaggcgaccgatgggcaccgcttcgtcgacggggcgtttgcg
gcgggggccgcaggcgcgatcgtcagcgacgccgtcaatggcccgcatgtgcgggtcgcc
gataccgtcgccgcgctggatgcgctgggggctgcgagccgcgcgcggaccaacgccaag
atcatcggcgtcaccggatcggtgggcaagacgggcaccaaggaagcgttgttcgccgcc
ttcgatcgggcggcgccgggcgctgcgcaccgttcgctaaaaagctacaacaaccatgtc
ggggtgccgctcagcctggcgcggatgccggccgatacccggtacggcgtattcgaaatg
gggatgagtgcggcgggcgaactggcggcgctgacccggctggtccgcccgcacgtcgcc
gtcgtcaccacgatcgcgccggcgcacagcgccttcttcgccagcgaggaggcgatcgcc
gatgccaagggggaaattttccaggggctggagccgggcggcaccgcgatcatcccgttc
gatagcccgcatcgcgaccggctgatcgccgccgccaggccatatgctggccgtatctgg
acattcgggcgcggcgaaggcgcggacatccgcgcgcgcgaagcggtgcgcggccatcgc
ggcacgctgatcgccgccaccctgccgggggccgaactgaccttttcactcgccccgccg
ggggatcattgggtggctaatgcgatggcggtgatcgccgccgtccacgccgtcgacggc
gatctggcggcggccgggcttgcgctggccgacatggcgggactcgccgggcgtggccgg
cgggtgacggcacgggtacgcgacggcgatgcgctggtgatcgacgaaagctataatgcg
aaccccgcgtcgatggcggcgacgatcgcgcttttgggcgaggaaaaagccggtcggcgg
atcgtggtgctgggcgacatgcgcgaactgggtgagaagtcacccgtttatcacgccgcg
ctggcgcagccgctggcgcaggcgaacgtcgatttcgccctgctggtcggccccgagatg
gcggcgctcgcgaatgagcttgagggccgcgtggatttcgcgcatgtgcccgacgccgcg
gccgcccttgcgcgcatcgatgacctcatcgaagccggcgatgcggtgctgattaaaggg
tccaacgccatcggactcgcccgtcttgtcgagcatctcggctcgggggcggtggccgcc
gggaacaagccatgctctatctga
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