Streptomyces platensis: CP981_10345
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Entry
CP981_10345 CDS
T07341
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
spla
Streptomyces platensis
Pathway
spla00300
Lysine biosynthesis
spla00550
Peptidoglycan biosynthesis
spla01100
Metabolic pathways
spla01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
spla00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
CP981_10345 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
CP981_10345 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
CP981_10345 (murF)
Enzymes [BR:
spla01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
CP981_10345 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
QEV52007
UniProt:
A0AAE6TLV3
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All DBs
Position
complement(2389082..2390530)
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AA seq
482 aa
AA seq
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MISLSLAEIASIVGGQQHDIPDDGHRVTGPVVADSRAVCPGALFVAFAGERVDGHDFAHR
AVEAGAVAVLAARPLGVPAIVVDDVVAALGALARAVVARLGTTVVGLTGSAGKTSTKDLI
AQLLQRHGPTVWPEGNLNNEIGLPLTALRADETTRHLVLEMGARGVGHIRYLAGLTPPRI
GVVLNVGSAHIGEFGGREQIALAKGELVESLPPAEDGGVAVLNADDPYVRAMVPRTRART
ILFGEAEEADVRAENVRLTDLGQPAFTLRTPSGCSDVTMRLYGEHHVSNALAAAAVAHEL
GMPADEIATALSEAGTLSRWRMEVTERADGVRIVNDAYNANPESMRAALRALVAMGAAGK
ATGARTWAVLGEMAELGEESLAEHDAVGRLAVRLNVSKLVAVGGREAAWLDMGAKNEGSW
GEESVHVSDARAAVDLLRSELRPGDVVLVKASRSVGLERVAAALLDEGMLGATGAEGGAA
SR
NT seq
1449 nt
NT seq
+upstream
nt +downstream
nt
gtgatctccctgtcgctcgccgagatcgcgagcatcgtcggagggcagcagcacgacata
ccggacgacggccaccgggtgaccggaccggtcgtggccgactcccgtgcggtgtgcccc
ggcgcgctgttcgtggccttcgccggtgaacgcgtcgacggccatgacttcgcgcaccgc
gccgtcgaggccggcgcggtggccgtactggccgcccgccccctcggcgtccccgcgatc
gtcgtcgacgacgtggtcgccgcgctcggtgcgctcgcccgcgccgtcgtcgcacggctg
ggcaccaccgtcgtgggtctgaccggctcggccggcaagaccagcaccaaggacctgatc
gcccagctgcttcagcgccacggcccgacggtctggcccgagggaaacctcaacaacgag
atcgggctgccgctgaccgcgctgcgcgccgatgagaccacccggcatctcgtcctggag
atgggcgcccgcggcgtcggccacatccgctacctcgccgggctgaccccgccgaggatc
ggcgtggtgctgaacgtcggcagcgcgcacatcggcgagttcggcggccgtgagcagatc
gccctggccaagggcgaactcgtcgagtcgctgccgccggccgaggacggcggcgtcgcg
gtgctcaacgccgacgacccgtacgtccgcgccatggtgccgcgcacccgggcccgcacg
atcctgttcggcgaggccgaggaagccgacgtacgtgccgagaatgtccggctcacggat
cttggtcagcccgctttcacgcttcgcacaccctccgggtgcagtgatgtgaccatgcgg
ctgtacggtgagcaccacgtgtcgaacgcgctcgccgcggccgccgtagcccatgagttg
ggcatgcccgcagacgagatcgctaccgcgctctccgaagccggcacgctctcccgctgg
cgtatggaggtcaccgagcgcgcggacggcgtgcggatcgtcaacgacgcctacaacgcg
aatcccgagtccatgcgagcggcgctgcgtgcgctggtcgcgatgggcgcagccggcaag
gcgacgggcgctcgtacgtgggcggtgctcggtgagatggctgagctcggcgaggagtca
ctcgccgaacacgacgcggtcgggcggctggccgtccggctcaacgtcagcaagctcgtg
gcagtcggcggcagggaagcggcctggctcgacatgggcgccaagaacgagggttcgtgg
ggtgaggagtcggtgcacgtgtccgacgcgcgggcggcggtcgacctgttgcgcagcgag
ctgcggccgggagatgtcgtgctggtgaaggcgtccaggtcggtggggctggagcgggtc
gccgcagctttgctggacgagggcatgctgggcgccacgggcgctgagggtggagccgca
tcccgatga
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