Streptomyces platensis: CP981_27645
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Entry
CP981_27645 CDS
T07341
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
spla
Streptomyces platensis
Pathway
spla00290
Valine, leucine and isoleucine biosynthesis
spla00660
C5-Branched dibasic acid metabolism
spla01100
Metabolic pathways
spla01110
Biosynthesis of secondary metabolites
spla01210
2-Oxocarboxylic acid metabolism
spla01230
Biosynthesis of amino acids
Module
spla_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
spla00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
CP981_27645 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
CP981_27645 (leuC)
Enzymes [BR:
spla01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
CP981_27645 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
CP981_27645 (leuC)
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
QEV54903
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Position
6220287..6221717
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AA seq
476 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRKAGRQVRRTDLTIAT
EDHNTPTLDIDKPIADPVSRTQLETLRKNCAEFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLAPFKTMAITVDGELPEGVTA
KDLILAIIARIGTGGGQGYVLEYRGSAIEKLSMEARMTICNMSIEAGARAGMIAPDETTF
DYLQGRDHAPQGEDWDAAVAYWKTLRTDDDAVFDAEVRIDASALAPFVTWGTNPGQGAPL
SASVPDPASYEDASERFAAEKALEYMGLTAGQPLRDIKVDTVFVGSCTNGRIEDLRSAAG
ILEGRKVADGVRMLIVPGSVRVSLEAVAEGLDKVFTAAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLSDVAVATPAGV
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
atgggacggacactcgcggagaaggtctgggacgaccatgtcgtccggcgcgcggaaggc
gagcccgacctcctcttcatcgatctgcacctgctgcacgaggtcaccagcccgcaggcg
ttcgacggcctccgcaaggccggccgccaggtgcgccggacggacctgaccatcgccacc
gaggatcacaacaccccgaccctcgacatcgacaagccgatcgccgacccggtctcccgc
actcagctggagacgctgcgcaagaactgcgcggagttcggggtccggctgcacccgctg
ggcgatgtcgagcagggcgttgtccacgtcgtgggaccgcagttgggactgacccagccc
ggcaccaccgtggtctgcggtgacagtcatacctccacccacggagccttcggcgcgctg
gcgttcggcatcggcaccagccaggtcgagcatgtgctggccacccagacgctgccgctg
gcccccttcaaaaccatggcgatcaccgtcgacggtgagctgcccgagggtgtcaccgcc
aaggacctgatcctggcgatcatcgcccggatcggcaccggcggcggccagggctatgtc
ctggaataccgcggttcggccatcgagaagctgtcgatggaagcccggatgaccatctgc
aacatgtcgatcgaggcgggcgcccgggccggcatgatcgccccggacgagaccaccttc
gactacctccagggccgtgaccacgccccgcagggcgaggactgggacgccgcggtcgcg
tactggaagacgctgcgcaccgacgacgacgcggtcttcgacgccgaggtgcgcatcgac
gcctccgcgctcgcgccgttcgtcacctggggcaccaaccccggccagggcgcgccgctt
tcggcgagcgtccccgacccggcttcgtacgaggacgcctcggagcgcttcgccgccgaa
aaggccctggagtacatggggttgacggcgggtcagccgctgcgggacatcaaggtggac
accgtcttcgtaggttcgtgcaccaacggccgtatcgaggacctgcgctccgcggccggg
atcctggaaggccgcaaggtcgccgacggcgtacggatgctgatcgtccccggctcggtc
cgggtctccctggaggccgtcgccgaggggctggacaaggtcttcaccgcggcgggcgcc
gaatggcggcacgcgggctgctcgatgtgcctgggcatgaaccccgaccagctggcgccc
ggtgagcgctccgcgtccacctccaaccgcaacttcgagggccggcagggcaagggcggt
cgtacgcacctggtctcgccgcaggtcgccgccgcaacggcggttctcggccatctggcc
tcaccggccgatctgtccgatgtcgccgtcgccacgcccgcgggagtctga
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