Streptomyces pluripotens: LK06_007305
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Entry
LK06_007305 CDS
T04845
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
splu
Streptomyces pluripotens
Pathway
splu00300
Lysine biosynthesis
splu00550
Peptidoglycan biosynthesis
splu01100
Metabolic pathways
splu01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
splu00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
LK06_007305
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
LK06_007305
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LK06_007305
Enzymes [BR:
splu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
LK06_007305
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
DUF2126
DHHA1
Motif
Other DBs
NCBI-ProteinID:
ARP69791
UniProt:
A0A221NVL8
LinkDB
All DBs
Position
complement(1655885..1657300)
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AA seq
471 aa
AA seq
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MIALSLAEIAAVVGGQTHDIPDPSVQVTGPVVRDSREVRQGSLFAAFVGERVDGHDYAQA
VVGAGAVAVLASRPVGVPAIVVADVQTALGALARYVVRRLGATLVALTGSAGKTSTKDLI
AQVLQRRAPTVFTPGSLNNEIGLPLTALSATEETRFLVLEMGARGIGHIHYLTGLTPPKI
GLVLNVGTAHIGEFGGREQIAQAKGELVEALPAAEDGGAAILNADDPLVRAMATRTKAKV
VLFGESAEADVRAENVRLTDSGQPVFRLHTPSGASDVTMRLYGEHHVSNALAAAAVAHEL
GMSAEEIAIALSEAGSLSRWRMEVTERPDGVTIVNDAYNANPESMRAALRALAAMGKGRR
TWAVLGKMAELGDEALAEHDAVGRLAVRLNVSKLVAVGGIEASWLQLGAYNEGSWGEESV
HVSDAQAAIDLLRSELRPGDAVLVKASRSVGLESVAQALVESGAEGEVAAR
NT seq
1416 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctccctcgccgagatcgccgcagtcgtcggcgggcagacgcatgacata
ccggatccgtccgtgcaggtcacgggaccggtcgttagggattcccgggaggttcggcaa
ggcagcctcttcgcagccttcgtcggtgagcgcgtcgacggccatgactacgcccaggcg
gtggtcggggccggcgcggtcgccgtgctggcgtcccggccggtcggggtgcccgcgatc
gtggtcgcggacgtccagacggctctcggtgccctggcccggtacgtggttcgccggctc
ggtgccaccctcgtcgccctgaccgggtccgcgggcaagaccagcaccaaagacctgatc
gcccaggtgctccagcgcagggcgccgaccgtgttcacacccggatcgctcaacaacgag
atcgggctgccgctgaccgccctgtccgccaccgaggagaccaggttcctcgtgctggag
atgggcgcccgcggtatcgggcacatccactacctcaccggactcacgcccccgaagatc
ggcctcgtcctcaacgtcggcaccgcgcacatcggtgagttcggcggacgcgagcagatc
gcccaggccaagggcgaactggtggaggcgctgcctgcggccgaggacggcggggccgcg
atcctcaacgcggatgatccgctggtccgggccatggccacccgtaccaaggcgaaagtg
gtccttttcggagagtcggccgaagcggacgtacgggcggagaacgtgcgactcacggac
agtggacagccggtcttcagacttcacacaccctccggtgcaagcgatgtgacgatgcgc
ctgtacggtgagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgagctg
ggcatgtccgcggaagagatcgccatcgcgctctccgaggcgggctccctctcccgctgg
cgcatggaggtcaccgagcgcccggacggcgtgaccatcgtcaacgacgcctacaacgcc
aaccccgagtccatgcgggccgctctcagggcgctcgcggccatgggcaaggggcgccgc
acgtgggcggtgctcggcaagatggccgagctgggggacgaggcgctcgccgagcacgac
gccgtcgggcggctcgccgtccggctcaacgtcagcaagctcgtcgccgtcggggggatt
gaggcctcctggctgcaactgggcgcatataacgagggttcgtggggtgaggagtcggtg
cacgtgtccgacgcacaggcggcgatcgacctgttgcgcagcgagttgcgcccgggggac
gccgtactcgtgaaggcgtcccgttcggtggggctggagagcgttgcccaggcgctcgtc
gagagcggtgccgagggtgaggttgccgcccgatga
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