Streptomyces pluripotens: LK06_013520
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Entry
LK06_013520 CDS
T04845
Name
(GenBank) dihydroxy-acid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
splu
Streptomyces pluripotens
Pathway
splu00290
Valine, leucine and isoleucine biosynthesis
splu00770
Pantothenate and CoA biosynthesis
splu01100
Metabolic pathways
splu01110
Biosynthesis of secondary metabolites
splu01210
2-Oxocarboxylic acid metabolism
splu01230
Biosynthesis of amino acids
Module
splu_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
splu_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
splu00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
LK06_013520
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
LK06_013520
Enzymes [BR:
splu01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
LK06_013520
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Motif
Pfam:
ILVD_EDD_N
ILV_EDD_C
DUF4154
Motif
Other DBs
NCBI-ProteinID:
ARP70809
UniProt:
A0A221NZ24
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Position
complement(3034367..3036220)
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AA seq
617 aa
AA seq
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MPELRSRTVTHGRNMAGARALMRASGVPSVDIGRKPIIAVANSFTEFVPGHTHLQPVGRI
VSDAIREAGGIPREFNTIAVDDGIAMGHGGMLYSLPSRDLIADSVEYMAEAHCADALVCI
SNCDKITPGMLMAALRLNIPTVFVSGGPMESGRATLVDGTVRTLDLVDAISDAVNDKISD
EDILRIEENACPTCGSCSGMFTANSMNCLTEAIGLSLPGNGSVLATHTARKQLYVDAART
VMDLTRRYYEQDDDSALPRSIASLPAFENAMALDIAMGGSTNTILHLLAAAQEAGVPFGL
EQIDAVSRRVPCLAKVAPNVGKNRTYYMEDVHRAGGIPALLGELHRAGLLNEDVHAVHSP
SLADWLKTWDVRGGSPSPEAVELWHAAPGCVRSAEAFSQSERWEALDDDAENGCIRSVEH
AYSKDGGLAVLKGNLATDGCVVKTAGVDESIWTFEGPAVVCESQEEAVQRILTQEVKDGD
VVVIRYEGPKGGPGMQEMLYPTSYLKGRGLGKSCALITDGRFSGGTSGLSIGHASPEAAS
GGTIALVQDGDRIRIDIPGRTIALLVDEAELARREHALNGVYAPRNRDRKVSAALRAYAA
MATSADKGAVRDVSKLG
NT seq
1854 nt
NT seq
+upstream
nt +downstream
nt
atgcccgagctgaggtcccgcacagtcacccacggccgcaacatggcgggcgcccgcgcc
ctgatgcgtgcctccggtgtacccagtgtggacatcggccggaagccgatcatcgccgtc
gcgaactccttcaccgagttcgtgcccggccacacccacctgcagccggtcggccggatc
gtcagcgacgcgatcagggaggccggcggcatcccgcgcgagttcaacacgatcgccgtg
gacgacggcatcgcgatgggccacggcggcatgctgtacagcctgccgtcccgcgacctg
atcgccgactcggtggagtacatggccgaggcccactgcgccgacgccctggtctgcatc
tccaactgcgacaagatcaccccgggcatgctgatggcggcgctgcgcctgaacatcccg
acggtcttcgtctcgggcggtcccatggagtccggccgcgccaccctcgtcgacggcacg
gtccgcacgctcgacctggtcgatgcgatctccgacgccgtgaacgacaagatctcggac
gaggacatcctgcgcatcgaggagaacgcctgcccgacctgcggcagctgttccgggatg
ttcaccgccaactcgatgaactgcctcaccgaggccatcggcctctccctgcccggtaac
ggctcggtcctcgccacccacaccgcccgcaagcagctctacgtcgacgcggcccgtacg
gtcatggacctcacccgccgctactacgagcaggacgacgactcggccctgccccgcagc
atcgcctccctcccggccttcgagaacgcgatggccctggacatcgcgatgggcggctcc
accaacacgatcctgcacctgctggccgcagcccaggaggcgggcgtgcccttcggcctg
gagcagatcgacgcggtctcccgccgcgtcccctgtctggccaaggtcgccccgaacgtc
gggaagaaccgcacgtactacatggaggacgtgcaccgggccggcggcatccccgccctc
ctcggcgaactgcaccgcgccggtctcctcaacgaggacgtccacgcggtccacagcccc
tctctcgcggactggctgaagacgtgggacgtccgtggtggctccccgtcccccgaggcc
gtggagctgtggcacgcggcccccggctgcgtccgctccgccgaggcgttctcccagtcg
gagcgttgggaggccctggacgacgacgccgagaacggctgcatccgctcggtcgagcac
gcgtactccaaggacggcggccttgccgtgctcaagggcaacctggccaccgacggctgc
gtggtgaagacggccggcgtcgacgagtccatctggaccttcgagggccccgccgtggtc
tgtgagtcccaggaggaggccgtgcagcggatcctcacccaggaggtcaaggacggcgac
gtggtcgtcatccgctacgagggtcccaagggcggccccggcatgcaggagatgctgtac
ccgacctcgtacctgaagggccggggcctcggcaagagctgcgcgctgatcaccgacggc
cgcttctccggtggtacgtccggtctctccatcggccacgcctcccccgaggcggcctcc
ggcggaaccatcgccctggtccaggacggtgaccgcatccgcatcgacatccccggccgc
accatcgcgctgctcgtcgacgaggcggaactcgctcggcgcgagcacgccctgaacggc
gtgtacgcccccaggaaccgcgaccgcaaggtctccgccgcgctccgtgcctacgcggcg
atggcgaccagcgcggacaagggcgcggtgcgcgacgtgagcaagctgggctga
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