Serratia inhibens: Q5A_002930
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Entry
Q5A_002930 CDS
T04576
Symbol
thrA
Name
(GenBank) Bifunctional aspartokinase/homoserine dehydrogenase 1
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
sply
Serratia inhibens
Pathway
sply00260
Glycine, serine and threonine metabolism
sply00261
Monobactam biosynthesis
sply00270
Cysteine and methionine metabolism
sply00300
Lysine biosynthesis
sply01100
Metabolic pathways
sply01110
Biosynthesis of secondary metabolites
sply01120
Microbial metabolism in diverse environments
sply01230
Biosynthesis of amino acids
Module
sply_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
sply_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
sply_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
sply00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
Q5A_002930 (thrA)
00270 Cysteine and methionine metabolism
Q5A_002930 (thrA)
00300 Lysine biosynthesis
Q5A_002930 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
Q5A_002930 (thrA)
Enzymes [BR:
sply01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
Q5A_002930 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
Q5A_002930 (thrA)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
ANS41079
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All DBs
Position
620956..623415
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AA seq
819 aa
AA seq
DB search
MRVLKFGGTSVANAERFLRVADIMESNARQGQVATVLSAPAKITNHLVAMIEKTVAGQDI
LPNMSDAERIFADLLSGLAQALPGFEYDRLKTLVDQEFAQLKQVLHGVALLGQCPDSVNA
AIICRGEKLSIAIMEGVFRAKGFPVTVINPVEKLLAQGHYLESTVDITESTLRIAAAAIP
ADHIVLMAGFTAGNDKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRTV
PDARLLKSMSYQEAMELSYFGASVLHPRTIAPIAQFQIPCLIKNTSNPQAPGTLIGGENV
DSDTPVKGITNLNNMAMINVSGPGMKGMIGMAARVFAVMSRTGISVVLITQSSSEYSISF
CVPQSELQRARRALEDEFYLELKDGLLEPLDVMEKLAIISVVGDGMRTLRGISARFFSAL
ARANINIVAIAQGSSERSISVVVSNDSATTGVRVCHQMLFNTDQVIEVFVIGVGGVGGAL
IEQIYRQQPWLKQKHIDLRICGIANSRAMLTNVHGIALDSWNEELAAAKEPFNLGRLIRL
VKEYHLLNPVIVDCTSSQAVADQYADFLADGFHVVTPNKKANTSSMNYYQQLRTAAAGSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELTRFSGILSGSLSFIFGKLDEGMSLSAATLEA
RAKGYTEPDPRDDLSGMDVARKLLILAREAGHKLELEDIEVESALPPSFDASGDVETFLA
RLPELDKEYARNVANAAEQGKVLRYVGVIEDGRCQVRIDAVDGNDPLYKVKNGENALAFY
SRYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgctgaaatttggcggaacctcggtagcgaatgcagaacgttttctgcgcgtt
gccgacatcatggaaagtaacgcacgtcagggacaggtagccacggtactgtccgcgcct
gcaaagatcaccaatcacttggtggcgatgattgaaaaaacggtggccgggcaagacatt
ctgccaaatatgagcgatgcggagcgtatcttcgcagatctgctgagcggcctggcgcag
gctctgccaggttttgaatacgatcgcctgaagaccctggtcgatcaggagttcgcccaa
ctgaagcaggtgctgcacggcgtagcgctgctggggcagtgcccggacagtgtgaacgcg
gcgattatctgccgtggcgagaaactctccatcgccatcatggaaggcgtattccgcgcc
aaaggtttcccggtgacggtgatcaacccggtagagaagctgttggcccaagggcattat
ctggagtcgactgtagatatcaccgaatccacgttgcgcatcgccgcagcggctatcccg
gcggatcatatcgtgctgatggccggtttcaccgccggtaatgacaaaggtgagctggtg
gtgctgggccgtaacggttccgactactctgccgcggtgctggccgcttgtctgcgcgca
gactgttgcgagatctggaccgacgtcgatggcgtttatacctgcgacccgcgcaccgta
ccggacgccaggttgctgaaatcgatgtcgtaccaggaggcgatggagctttcctatttc
ggcgccagcgtgcttcacccccgtactatcgccccgattgcccagttccaaatcccttgc
ctgatcaaaaacacgtccaatccgcaggcccccggcacgctgatcggcggtgaaaatgtg
gatagcgataccccggtaaagggcatcaccaatctgaacaacatggcgatgatcaacgtt
tccgggccggggatgaaggggatgatcggcatggccgcgcgggtgttcgccgtgatgtcg
cgcaccggtatttcggtggtgctgattacccaatcctcttccgagtacagcatcagcttc
tgcgtgccgcagagcgaattgcagcgtgcgcgccgtgcgctggaagacgaattctacctt
gagctgaaagacggcttgcttgagccgctggacgtgatggaaaagctggcgattatctcg
gtcgtgggcgacggcatgcgcaccctgcgcggcatctcggcccgcttcttctccgcgctg
gcgcgcgccaatatcaacattgtcgccatcgctcagggctcgtcggagcgttccatctcg
gtggtggtcagcaacgattccgccaccaccggcgttcgcgtctgccaccagatgctgttc
aataccgatcaggtgattgaagtgtttgtcatcggcgtcggtggcgtcggcggtgcgttg
atcgagcagatttatcgccagcagccatggctgaagcaaaagcatatcgatctgcgcatc
tgcggtatcgccaattcccgagccatgttgaccaatgtgcacggcattgctctggacagc
tggaacgaggaactggccgcggctaaagaaccgttcaatcttggccgcctgatccgtctg
gtgaaggagtaccacctgctgaacccggtgatcgtcgactgtacttccagccaggcggtt
gccgaccagtacgcggatttcctggccgatggtttccacgtggtgacgccgaacaagaag
gccaatacttcgtcgatgaattactatcaacagctgcgcaccgctgctgccggttcacgt
cgcaagttcctgtacgacaccaacgtcggtgcgggcttgccggtgattgagaacctgcaa
aatctgctgaacgccggcgatgagctgacgcgtttctccggcatcctgtccggttcgctg
tcatttattttcggtaagctggacgaaggcatgtcgctgtcggcagcgaccctggaggcc
agagccaaagggtacaccgagccggatccgcgcgacgatctgtccggtatggacgttgcc
cgcaagcttttgatcctggcccgcgaagcgggtcacaaactggagttggaggacattgag
gtcgagtcggcactgccgccgtcctttgacgcttccggcgatgtggaaaccttcctggca
cgcctgccggagctggataaagaatatgcccgcaacgtggctaacgccgccgagcagggt
aaggtgttgcgctatgtcggcgtgatcgaagatggccgctgtcaggttcgcattgatgcg
gtagacggcaacgatccgttgtataaagtgaagaacggtgagaacgccctggccttctac
agccgttattatcaaccattacccttggtgctgcgcggctacggcgccggtaatgatgtg
actgcggcgggggtatttgccgacctgttgcgcacactgtcatggaagttgggagtttaa
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