Serratia inhibens: Q5A_003220
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Entry
Q5A_003220 CDS
T04576
Symbol
leuA_1
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
sply
Serratia inhibens
Pathway
sply00290
Valine, leucine and isoleucine biosynthesis
sply00620
Pyruvate metabolism
sply01100
Metabolic pathways
sply01110
Biosynthesis of secondary metabolites
sply01210
2-Oxocarboxylic acid metabolism
sply01230
Biosynthesis of amino acids
Module
sply_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sply00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Q5A_003220 (leuA_1)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Q5A_003220 (leuA_1)
Enzymes [BR:
sply01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Q5A_003220 (leuA_1)
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Gene cluster
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Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
IPMS_D2
Motif
Other DBs
NCBI-ProteinID:
ANS41137
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Position
complement(691533..693107)
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AA seq
524 aa
AA seq
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MSQQVIIFDTTLRDGEQALQASLSVKEKIQIAMALERMGVDVMEVGFPVSSPGDFESVQT
IARQIKNSRVCGLARCVDNDIDVAAEALRVAEAFRIHVFLATSTLHIESKLKRSFDEVLE
MAVRSVKRARNYTDDVEFSCEDAGRTPIDNLCRVVEAAINAGATTINIPDTVGYTTPNQF
GGIITTLYDRVPNIDKAIISVHCHDDLGMAVGNSIAAVQAGARQVEGTLNGIGERAGNTS
LEEVIMAIKVRQDIMNVHTNINHQEIFRTSQLVSQLCNMPIPANKAIVGSNAFAHSSGIH
QDGVLKNRENYEIMSPQTIGLKDVQLNLTSRSGRAAVKHRMEEMGYKEQDYNLDTLYTAF
LKLADKKGQVFDYDLEALAFINKQQEEPEHFSLGYFSVQSGTNIMATASVKLICGDEEKA
EAATGNGPVDAVYQAINRITDYPIELVKYQLTAKGQGRDALGQVDIVVSYNGRRFHGVGL
ATDIVESSAKAMVHVLNNIWRSQQVEKEKQRLQQSKHQNNQETV
NT seq
1575 nt
NT seq
+upstream
nt +downstream
nt
atgagccaacaagtcattattttcgataccacgctgcgtgatggtgaacaagcgctgcaa
gccagtctgagcgtaaaagagaagattcagatagccatggcactggagagaatgggcgtc
gacgtaatggaagtcggtttcccggtatcctctccgggtgattttgaatcggtgcagacc
atcgcccgtcagatcaaaaacagccgcgtctgtggcctggcccgctgcgtagataacgat
atcgacgtcgccgcagaagcgctgcgcgtcgccgaggccttccgcattcacgtcttcctg
gccacatcgaccctgcacatcgaatccaaattgaagcgctcgttcgatgaagtgctggag
atggcggtacgctcggtgaaacgcgcccgcaactacactgacgatgtggagttctcttgc
gaagacgccggccggacgccgatcgataatctgtgccgtgtcgtggaagccgccatcaac
gccggtgccaccaccatcaatatcccggacaccgtcggctataccacgccgaaccagttc
ggcggcatcatcaccacgctgtatgaccgcgtcccgaacattgataaagccattatttcg
gtccactgtcacgacgatctgggcatggcggtaggtaactccatcgccgccgtacaggca
ggtgcgcgccaggtagaaggtacgttgaacggtatcggcgaacgcgccggcaacacctcg
ctggaagaagtgatcatggcgatcaaagtgcgccaggacatcatgaacgtgcacaccaac
attaatcatcaggaaatcttccgcaccagccaattggtcagccagctgtgcaatatgcca
attccggccaacaaagctatcgtgggttccaacgccttcgcccactcctccggcattcat
caggacggtgtgctgaagaaccgcgaaaattacgaaatcatgtccccgcagaccataggt
ctgaaagacgtgcagttgaacctgacctcccgttccggccgcgctgcggtaaaacaccgc
atggaagagatgggctataaggaacaggactacaacctggacactctgtacaccgctttc
ctgaagctggccgacaagaaaggccaggtgttcgattacgatctggaggctttagccttc
attaataagcagcaggaagagccggagcatttcagcctgggctatttcagcgtgcagtcc
ggcaccaacattatggccaccgcctcggtgaaactgatctgcggcgatgaagaaaaagcc
gaagcggcaaccggcaacggcccggtcgacgcggtttatcaggccatcaatcgcattacc
gattacccgatcgaattagtgaagtatcagttgaccgccaaaggccagggccgcgacgca
ctgggccaggttgatatcgtggtgtcctacaacggccgccgcttccatggcgtgggtctg
gcgaccgacatcgtggaatcctccgccaaggcgatggttcacgtattgaacaatatttgg
cgctcccagcaggtagaaaaagaaaaacagcgtctgcagcaaagcaaacatcaaaataat
caggaaacggtgtga
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