Streptococcus pneumoniae TIGR4 (virulent serotype 4): SP_0045
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Entry
SP_0045 CDS
T00057
Name
(GenBank) putative phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
spn
Streptococcus pneumoniae TIGR4 (virulent serotype 4)
Pathway
spn00230
Purine metabolism
spn01100
Metabolic pathways
spn01110
Biosynthesis of secondary metabolites
Module
spn_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
spn00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
SP_0045
Enzymes [BR:
spn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
SP_0045
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
GATase_3
FGAR-AT_PurM_N-like
DJ-1_PfpI
Motif
Other DBs
NCBI-ProteinID:
AAK74234
UniProt:
A0A0H2UMW6
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All DBs
Position
45410..49135
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AA seq
1241 aa
AA seq
DB search
MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDVFDLAEDLFAPAEKHIF
SEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQEALLLLGSSSDVTVNTAQL
YLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFSESDKTIPKLTFFESYAAEDF
ARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVLDTYWSDHCRHTTFETELKHIDF
SASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMATIFGRYERANGRLDDMEVSDEINA
CSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPFGGAATCIGGAIRDPLSGRSYVYQAMR
ISGAGDITAPISETRAGKLPQQVISKTAAHGYSSYGNQIGLATTYVREYFHPGFVAKRME
LGAVVGATPKGNVVREKPEAGDVIILLGGKTGRDGVGGATGSSKVQTVESVETAGAEVQK
GNAIEERKIQRLFRNGNVTRLIKKSNDFGAGGVCVAIGELADGLEIDLNKVPLKYQGLNG
TEIAISESQERMAVVVRPEDVDAFVAECNKENIDAVVVATVTEKPNLVMHWNGETIVDLE
RRFLDTNGVRVVVDAKVVDKDVKLPEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDC
SVGRSTVNHPLGGRYQLTPTEASVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYA
VIEATARLVAAGANWFKARFSYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGG
KDSMSGTFEELTVPPTLAAFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIK
KNFAQFEAIQADHKVTSASAVKYGGVVESLALATFGNYIGAEVTLPELETALTAQLGGFV
FTSPEEIAGVEKVGQTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVP
AVASDVVIKAKEKVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKS
VETMVDNIDKTNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGIC
NGFQALVKSGLLPYGNFEAANSTSPTLFYNDANQHVAKMVETRIANTNSPWLVGVQVGDI
HAIPVSHGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSK
NGQIIGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK
NT seq
3726 nt
NT seq
+upstream
nt +downstream
nt
atggataaacgtatttttgttgaaaaaaaggctgattttcaggtcaagtcagagagtttg
gttagagagctccagcacaacttgggactgtcaagcttgaaaagtattcgtattgtgcaa
gtatatgatgtatttgacttggctgaggacttgtttgcacctgcagagaagcacattttc
tctgagcaggtaaccgaccatgttttagatgaagtatctgtgcaggcggatcttgctaac
tatgctttctttgccattgaaagtctgccagggcagtttgaccagcgtgcagcttcgtca
caggaagccttgcttttgttgggaagttcgagtgacgtgacagtcaacacagcccaactt
tacttggtgaataaagatattgatgcgactgagttggaagctgtcaaaaactacctgctc
aatccagttgattctcgtttcaaggatatcacgacagggattgccaagcaggagttttca
gagtcagacaagaccattcccaaattgactttctttgaaagctatgcagcagaagacttt
gctcgctacaaggccgaacaagggatggccatggaagtggatgatttgctctttatccaa
gactactttaagtcaatcgggcgcgtgccaactgagactgaactcaaggttttggacact
tactggtctgaccactgccgtcatacgacttttgagacagagttgaaacacatcgacttt
tcagcttctaaatttcaaaagcaattgcagtcaacctatgacaagtatattgccatgcgc
gaggaattaggtcggtctgaaaaaccacaaaccttgatggatatggcgactattttcggt
cgttatgagcgtgctaatggacgattggatgatatggaagtctctgacgaaatcaatgcc
tgctcagttgaaattgaagtggacgttgatggtgtcaaggaaccttggctcctcatgttt
aaaaacgaaacccacaaccatccaacagaaattgagccatttggtggagcggctacctgt
attggtggagctattcgtgatccgttgtcaggccgttcctatgtttaccaagccatgcgt
atttcaggtgctggtgatattacagcaccgatttcggaaactcgcgctgggaaattgcca
caacaagtcatttctaaaacagcagctcatggttattcttcatatggtaaccagattggg
cttgcaacaacctacgttcgtgaatacttccacccaggctttgtagctaaacgtatggaa
cttggtgccgttgttggtgcgactcccaagggcaatgttgtccgtgaaaaacctgaagca
ggtgatgtgatcatccttctcggaggcaaaacaggtcgtgatggtgtcggtggtgcgacg
ggctcttctaaggttcaaacagttgagtctgtagagactgctggtgctgaggttcaaaaa
ggaaatgccatcgaagaacgcaagattcagcgcctcttccgtaatggcaatgtcactcgt
ctgatcaagaagtccaatgactttggggcaggcggtgtctgtgtggctatcggtgaattg
gcagacggtcttgaaatcgacctcaacaaggtgcctcttaaataccagggcttgaatggt
acagaaattgccatctctgaatcacaagaacggatggcggtcgtggttcgtcctgaagat
gtggatgccttcgttgccgaatgtaacaaagaaaatattgatgctgttgtggtggcgaca
gtaactgaaaaaccaaatcttgtcatgcactggaatggtgagacaatcgttgacttggag
cgtcgtttccttgacaccaatggtgtgcgcgtggttgtcgatgccaaagttgtggacaag
gatgtcaaactcccagaagagcgtcaaacatctgctgaaacactggaatcagataccctt
acggttctatctgacctcaaccatgcaagtcaaaaaggattacagactatctttgactgc
tctgttggacgctcaacggttaatcacccacttggtggtcgttaccaactcacaccaact
gaggcatctgtgcagaaattgccagttcaacacggtgtgactcatactgcgtcggtcatt
gctcaaggtttcaacccatatgtagctgaatggtctccataccacggtgctgcttatgcg
gttatcgaagcaactgctcgtttggtggctgctggtgccaactggttcaaggctcgtttc
tcttaccaagagtatttcgagcgtatggataaacaagcagagcgtttcggtcagccagta
gctgctcttctaggttctattgaagcacaaattcagcttggcttgccatctatcggtggt
aaggactccatgtctggtacctttgaagaattgaccgttccgccaaccttggctgccttt
ggggtgacgacggcagatagccgtaaggtgctctctccagaatttaaagctgttggggaa
aatatctactacatcccaggtcaagccctctctgcagagattgattttgacttgattaag
aaaaattttgctcagtttgaagccatccaagctgaccataaagtgacatctgcatcagct
gtcaaatacggtggtgtagttgaaagtttggctcttgctacctttggaaactatattggt
gcagaggtgaccttgcctgaacttgaaacagctttgacagctcaattaggcggctttgtc
ttcacatctcctgaagaaattgctggagtagagaaggttggacaaacgaaagcagacttt
acactgactgtcaacggtgtgaagctagatggacacaagcttgacagtgcatttcaaggg
acattggaagaagtttacccaacagaatttacccaagcgaaagaactagaagaagtacca
gctgtggcatcagatgttgtgattaaagccaaagaaaaggttgaaaaacctgtggtttac
atcccagtctttccaggaaccaactcagaatatgattcagctaaggccttcgaaaaagaa
ggtgcagaggtcaatttggtgccattcgtgaccttgaatgaagaagctattgtcaagtca
gttgaaactatggttgacaatatcgacaagactaatattctcttctttgctggtggattc
tcggctgcggatgaaccagatggttcagctaagtttatcgtcaatatcctgcttaatgaa
aaagtgcgtgtggctattgatagctttatcgcccgtggtggtttgattatcggtatttgt
aatggattccaagccttagtcaaatcgggtctcctaccctacggaaactttgaagctgct
aacagtactagcccaaccctcttctacaatgatgccaaccaacacgtggccaagatggtg
gaaactcgcattgccaataccaactcaccatggttggttggtgtgcaagtgggcgatatc
cacgctattcctgtttcgcacggtgaagggaagtttgtcgtgacggctgaggaatttgca
gagctccgtgacaatggacaaattttcagccaatacgttgactttaacggtaaaccaagt
atggattctaagtacaatccgaatggttctgtccatgccatcgaaggaattaccagcaag
aatggtcaaatcatcggtaagatgggccactcagaacgttatgaggatggtcttttccaa
aatatcccaggcaataaagaccaacacctgttcgcatcagcggttaaacatttcactgga
aaataa
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