Streptococcus pneumoniae TIGR4 (virulent serotype 4): SP_0585
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Entry
SP_0585 CDS
T00057
Symbol
metE
Name
(GenBank) 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
KO
K00549
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:
2.1.1.14
]
Organism
spn
Streptococcus pneumoniae TIGR4 (virulent serotype 4)
Pathway
spn00270
Cysteine and methionine metabolism
spn00450
Selenocompound metabolism
spn01100
Metabolic pathways
spn01110
Biosynthesis of secondary metabolites
spn01230
Biosynthesis of amino acids
Module
spn_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
spn00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
SP_0585 (metE)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
SP_0585 (metE)
Enzymes [BR:
spn01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.14 5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase
SP_0585 (metE)
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Gene cluster
GFIT
Motif
Pfam:
Meth_synt_2
Meth_synt_1
Motif
Other DBs
NCBI-ProteinID:
AAK74738
UniProt:
Q97S31
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All DBs
Position
554099..556348
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AA seq
749 aa
AA seq
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MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAKHWNIVKEKGITEIPSN
DFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQGEKGDVRALPMKKWFNTNY
HYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVGPFTFLQLSDFEEGVKADDFV
DSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEKALFLNLYNKLLADKKGLEVLLQ
TYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVKGGFPADKTLYVGIVNGKNIWRNNY
EKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEEFEPALLNHFAFAVEKLDEIRDLDAIR
NGQGSEALAANKELFATERVGENAELRARIAGLTDADYTRLPAFAEREAIQEEAFKLPAL
PTTTIGSFPQTKEVRAKRLAYRKGELSQKEYDAFLAETIDEWIKWQEDIDFDVLVHGEFE
RNDMVEYFGQNLSGYLFSKNGWVQSYGMRGVKPPIIWGDVTRLNPITVKWSSYAQSRTNK
PVKGMLTGPVTILNWSFPREDISIKDSTLQIALAIKDEVLDLEAAGVKIIQIDEAALREK
LPLRRSDWYEDYLDWAIPAFRLVHSTVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFE
ANRSNLEILDELKAKNFQTEVGPGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPD
CGLKTRGIPETKESLIRLVEAAKAAREKL
NT seq
2250 nt
NT seq
+upstream
nt +downstream
nt
atgtcaactacaatcatcggtttccctcgtttgggcgaattccgtgaattaaaatttaca
actgaaaaatactttagaaaagaaatctcagaagaagaacttttagcagcagcaaaagac
ttgcgtgctaaacactggaacattgtcaaagaaaaaggcatcactgaaattccatcaaat
gacttttctcactatgataacttcctagatgcggctttccttttcaacgtggtgcctgca
tccgttcaaaacttggacttgtctgaccttgagcgctacttcgctttgggacgtggttac
cagggagaaaaaggggacgttcgcgcccttccaatgaagaaatggttcaacactaactac
cactacatcgttcctaaatttgaaaaagacactcaagtaaaattggctggtcacaagatt
ttcgatgagttccaagaagccaaagaacttggattgaacactcgtcctgttcttgtaggt
cccttcactttccttcaattgtcagactttgaagaaggcgtgaaagcagacgacttcgta
gatagcttagtggctgcttaccaagaagtttttgctaaattggctgaacttggtgcgact
cgcatccaattggatgaagcggctcttgtaaaagacttgacagctgaagaaaaagctctc
ttcttgaacctttacaacaaactcttggctgacaaaaaaggtcttgaagtcttgcttcaa
acttatttcggtgatgttcgtgacgtatacgctgaccttgtaaacttaccagtagatgct
atcggtcttgactttgttgaaggtaagaaaactcttgaactcgttaaaggtggcttccca
gctgacaagactctctatgtaggtattgtcaatggtaaaaacatctggcgcaacaactac
gaaaagagcttggctgttcttgagcaaattccagctgaaaacatcgttttgacaagctct
tgctcacttcttcatgtgccatttacaactgctaatgaagaatttgaaccagcactcttg
aaccactttgcctttgcagttgaaaaattggatgaaatccgtgacttggatgctatccga
aatggtcaaggttcagaagctcttgcagccaacaaagaactctttgcgactgagcgtgtt
ggtgaaaatgctgaacttcgtgcgcgtatcgctggcttgacagacgcagactacactcgt
ttgccagcctttgcagaacgtgaagctatccaagaagaagctttcaaacttccagctctt
ccaacaacaacgattggttcattccctcaaacaaaagaagttcgtgccaaacgtttggct
taccgtaaaggtgaattgtctcaaaaagagtacgacgctttccttgctgaaacgattgac
gaatggatcaagtggcaagaagatattgactttgatgtccttgttcacggtgaatttgag
cgtaatgacatggttgagtacttcggtcaaaacttgtcaggatacctcttctctaaaaat
ggatgggtacaatcatacggtatgcgtggggtaaaaccaccaatcatctggggtgatgtc
actcgtcttaaccctatcactgttaaatggtctagctatgcacaaagtcgtacaaacaaa
cctgttaaaggtatgttgactggacctgttaccatccttaactggtcattcccacgtgaa
gacatctctatcaaggattcaactctccaaatcgcccttgctatcaaggatgaagtactt
gaccttgaagctgctggtgtgaaaatcatccaaatcgacgaggctgctcttcgtgaaaaa
ttgccactccgccgtagcgactggtacgaagactaccttgactgggctattcctgccttc
cgcttggtacactcaacagtagcgccagacacacaaatccacactcacatgtgttactca
gaatttacagatatcatcccagctatcgataacatggatgcagacgttatttcctttgaa
gctaaccgttcaaaccttgaaatcttggacgaactcaaagcgaaaaacttccaaacagaa
gtgggacctggggtttacgatatccactcacctcgtgtaccaaatgaaggcgaaatcgac
aacacaatcgaagccatccttgctaaagtgccaagcaagaaagtttggatcaaccctgac
tgtggtttgaaaacacgtggtatcccagaaacaaaagaaagcttgatccgccttgttgaa
gcagctaaagctgcgcgtgagaaattgtaa
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